aortic smooth muscle cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
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Genes

339 proteins co-occuring with the tissue aortic smooth muscle cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
ELN elastin 1.59275
PDGFB platelet-derived growth factor beta polypeptide 1.54632
JUN jun proto-oncogene 1.38642
IL1B interleukin 1, beta 1.34542
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 1.32506
MMP2 matrix metallopeptidase 2 1.32461
FGF2 fibroblast growth factor 2 (basic) 1.27202
FN1 fibronectin 1 1.27068
MAPK3 mitogen-activated protein kinase 3 1.22871
NPPA natriuretic peptide A 1.22247
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.202
MMP9 matrix metallopeptidase 9 1.198
EDN1 endothelin 1 1.18379
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.17891
MYH11 myosin, heavy chain 11, smooth muscle 1.16914
TGFB1 transforming growth factor, beta 1 1.16737
APOE apolipoprotein E 1.16116
IGF1 insulin-like growth factor 1 (somatomedin C) 1.15628
SPP1 secreted phosphoprotein 1 1.11907
NOX1 NADPH oxidase 1 1.10977
MYOCD myocardin 1.10579
FAM172A family with sequence similarity 172, member A 1.09341
FOS FBJ murine osteosarcoma viral oncogene homolog 1.09297
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 1.08943
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.08766
HMOX1 heme oxygenase 1 1.0859
MAPK14 mitogen-activated protein kinase 14 1.07529
F2R coagulation factor II (thrombin) receptor 1.04664
LOX lysyl oxidase 1.01856
CCND1 cyclin D1 0.971984
HBEGF heparin-binding EGF-like growth factor 0.956428
NOX4 NADPH oxidase 4 0.95384
GUCY2C guanylate cyclase 2C 0.95384
TNF tumor necrosis factor 0.952116
NPR1 natriuretic peptide receptor 1 0.951685
TAGLN transgelin 0.946087
PDGFA platelet-derived growth factor alpha polypeptide 0.941355
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.934054
PXN paxillin 0.919916
CALD1 caldesmon 1 0.912653
MAPK8 mitogen-activated protein kinase 8 0.90285
CDK4 cyclin-dependent kinase 4 0.899445
EDNRA endothelin receptor type A 0.89562
NPPC natriuretic peptide C 0.887981
INS insulin 0.88671
PPARG peroxisome proliferator-activated receptor gamma 0.885015
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.868951
MAPK7 mitogen-activated protein kinase 7 0.865155
SOD2 superoxide dismutase 2, mitochondrial 0.864312
KNG1 kininogen 1 0.856732
F3 coagulation factor III (thromboplastin, tissue factor) 0.855891
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.85547
VCL vinculin 0.842867
PRKG1 protein kinase, cGMP-dependent, type I 0.83993
FGF1 fibroblast growth factor 1 (acidic) 0.838672
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.836575
CDK2 cyclin-dependent kinase 2 0.834899
HYLS1 hydrolethalus syndrome 1 0.830291
DNAH8 dynein, axonemal, heavy chain 8 0.828197
CCL2 chemokine (C-C motif) ligand 2 0.819412
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.818158
NOS2 nitric oxide synthase 2, inducible 0.813562
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.813562
BDKRB1 bradykinin receptor B1 0.799791
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.795624
EGR1 early growth response 1 0.795208
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.791044
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.788547
TIMP2 TIMP metallopeptidase inhibitor 2 0.781478
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.77857
PLG plasminogen 0.777325
CXCL16 chemokine (C-X-C motif) ligand 16 0.776909
BGN biglycan 0.744627
PPARA peroxisome proliferator-activated receptor alpha 0.742564
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.733912
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.730208
CAT catalase 0.726918
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.725685
IGF1R insulin-like growth factor 1 receptor 0.721577
PRR11 proline rich 11 0.721577
AGER advanced glycosylation end product-specific receptor 0.717882
PCNA proliferating cell nuclear antigen 0.712139
CNN1 calponin 1, basic, smooth muscle 0.707221
AVP arginine vasopressin 0.704355
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.683511
PTHLH parathyroid hormone-like hormone 0.675357
NOS3 nitric oxide synthase 3 (endothelial cell) 0.671285
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.66925
TBXA2R thromboxane A2 receptor 0.665588
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.662742
CYBA cytochrome b-245, alpha polypeptide 0.65746
VCAN versican 0.656242
NPR3 natriuretic peptide receptor 3 0.653807
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 0.652183
VCAM1 vascular cell adhesion molecule 1 0.652183
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.6461
SLC35G5 solute carrier family 35, member G5 0.644074
TIMP1 TIMP metallopeptidase inhibitor 1 0.639214
ADCY2 adenylate cyclase 2 (brain) 0.627889
ALPL alkaline phosphatase, liver/bone/kidney 0.623043
ANG angiogenin, ribonuclease, RNase A family, 5 0.621024
RUNX2 runt-related transcription factor 2 0.620217
CTNNBIP1 catenin, beta interacting protein 1 0.610943
ALPPL2 alkaline phosphatase, placental-like 2 0.606112
ALPP alkaline phosphatase, placental 0.604904
COL21A1 collagen, type XXI, alpha 1 0.601283
THBS1 thrombospondin 1 0.597263
ELAVL1 ELAV like RNA binding protein 1 0.595255
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.592444
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.592444
MMP1 matrix metallopeptidase 1 0.59124
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.589635
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.587629
ACTG1 actin gamma 1 0.581618
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.576816
ZNF266 zinc finger protein 266 0.575616
SEBOX SEBOX homeobox 0.57082
LPP LIM domain containing preferred translocation partner in lipoma 0.57082
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.570021
CLCN3 chloride channel, voltage-sensitive 3 0.568823
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.568424
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.568025
RHOBTB1 Rho-related BTB domain containing 1 0.567626
LDLR low density lipoprotein receptor 0.566828
FHL1 four and a half LIM domains 1 0.566828
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.566828
FNDC1 fibronectin type III domain containing 1 0.566428
RRAD Ras-related associated with diabetes 0.562441
MYLK myosin light chain kinase 0.561644
ACTB actin, beta 0.559254
SMAD3 SMAD family member 3 0.558457
MSX2 msh homeobox 2 0.55408
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.55408
FBN1 fibrillin 1 0.552888
ADRA1B adrenoceptor alpha 1B 0.551695
PRDM6 PR domain containing 6 0.550901
ICAM1 intercellular adhesion molecule 1 0.548517
SYK spleen tyrosine kinase 0.54812
LARP6 La ribonucleoprotein domain family, member 6 0.54217
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 0.54217
AEBP1 AE binding protein 1 0.540188
JAK2 Janus kinase 2 0.532274
HAS2 hyaluronan synthase 2 0.532274
MAP2K1 mitogen-activated protein kinase kinase 1 0.531089
ACE angiotensin I converting enzyme 0.524377
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.523194
GJA1 gap junction protein, alpha 1, 43kDa 0.5228
SAA4 serum amyloid A4, constitutive 0.521223
ESR1 estrogen receptor 1 0.517678
PDE5A phosphodiesterase 5A, cGMP-specific 0.515317
MGP matrix Gla protein 0.512171
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.511778
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.503141
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.50275
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 0.502357
AHNAK AHNAK nucleoprotein 0.500007
PLCG1 phospholipase C, gamma 1 0.500007
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.496874
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.494136
GPR68 G protein-coupled receptor 68 0.489057
CTGF connective tissue growth factor 0.483206
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.477756
LPL lipoprotein lipase 0.473092
ELANE elastase, neutrophil expressed 0.471539
IL1A interleukin 1, alpha 0.470763
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.470763
MAPK1 mitogen-activated protein kinase 1 0.469987
IL6 interleukin 6 0.469987
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 0.465335
TPM1 tropomyosin 1 (alpha) 0.464174
BMP2 bone morphogenetic protein 2 0.461465
TNC tenascin C 0.460692
PTH1R parathyroid hormone 1 receptor 0.4576
MGAM maltase-glucoamylase 0.455284
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.452198
IGFBP4 insulin-like growth factor binding protein 4 0.451813
LIPA lipase A, lysosomal acid, cholesterol esterase 0.451813
PDGFC platelet derived growth factor C 0.447192
TP53 tumor protein p53 0.446807
MFAP2 microfibrillar-associated protein 2 0.446422
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 0.439507
BTG1 B-cell translocation gene 1, anti-proliferative 0.436055
ODC1 ornithine decarboxylase 1 0.435672
DGKA diacylglycerol kinase, alpha 80kDa 0.435289
HAS3 hyaluronan synthase 3 0.434523
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.43414
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.433757
PLA2G1B phospholipase A2, group IB (pancreas) 0.432991
SMTN smoothelin 0.432608
RNASEH2A ribonuclease H2, subunit A 0.432608
MMP3 matrix metallopeptidase 3 0.432608
BGLAP bone gamma-carboxyglutamate (gla) protein 0.430695
TLR4 toll-like receptor 4 0.429165
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.426872
COL19A1 collagen, type XIX, alpha 1 0.426872
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 0.415434
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.415434
PDE4D phosphodiesterase 4D, cAMP-specific 0.413532
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.411631
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.409731
NTPCR nucleoside-triphosphatase, cancer-related 0.406694
FGFR1 fibroblast growth factor receptor 1 0.404039
VEGFA vascular endothelial growth factor A 0.404039
S100A12 S100 calcium binding protein A12 0.402523
SCARB1 scavenger receptor class B, member 1 0.402144
CDH13 cadherin 13 0.399492
CD36 CD36 molecule (thrombospondin receptor) 0.398357
ALB albumin 0.396465
LPA lipoprotein, Lp(a) 0.391553
CREG1 cellular repressor of E1A-stimulated genes 1 0.390421
ESR2 estrogen receptor 2 (ER beta) 0.38552
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.38552
PLAT plasminogen activator, tissue 0.382884
CXCL8 chemokine (C-X-C motif) ligand 8 0.378748
PCNP PEST proteolytic signal containing nuclear protein 0.376494
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.369373
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.368624
GLB1 galactosidase, beta 1 0.367502
ANXA5 annexin A5 0.366381
CCR2 chemokine (C-C motif) receptor 2 0.366381
PPARD peroxisome proliferator-activated receptor delta 0.364886
CIB1 calcium and integrin binding 1 (calmyrin) 0.364513
SKI SKI proto-oncogene 0.363766
RPS12 ribosomal protein S12 0.358174
UCN urocortin 0.356314
CTSA cathepsin A 0.354826
OSM oncostatin M 0.35334
CD47 CD47 molecule 0.350372
DUSP1 dual specificity phosphatase 1 0.34963
FMN1 formin 1 0.34963
NPTXR neuronal pentraxin receptor 0.344079
CNOT7 CCR4-NOT transcription complex, subunit 7 0.34371
AGTR1 angiotensin II receptor, type 1 0.34334
PRKD1 protein kinase D1 0.342602
KL klotho 0.342233
OIT3 oncoprotein induced transcript 3 0.341126
MRVI1 murine retrovirus integration site 1 homolog 0.341126
REN renin 0.340388
PKN1 protein kinase N1 0.340388
VWF von Willebrand factor 0.33965
SCARB2 scavenger receptor class B, member 2 0.33744
PDE4A phosphodiesterase 4A, cAMP-specific 0.33744
DCN decorin 0.335968
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.333396
ARRB2 arrestin, beta 2 0.332294
ZRANB2 zinc finger, RAN-binding domain containing 2 0.331194
BRAP BRCA1 associated protein 0.329727
DGKE diacylglycerol kinase, epsilon 64kDa 0.328628
MMP7 matrix metallopeptidase 7 0.327896
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.327896
VASP vasodilator-stimulated phosphoprotein 0.327164
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.326798
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.324605
NCEH1 neutral cholesterol ester hydrolase 1 0.323509
IRS1 insulin receptor substrate 1 0.322414
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.320956
HYOU1 hypoxia up-regulated 1 0.320227
DGKQ diacylglycerol kinase, theta 110kDa 0.319498
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.319134
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.31877
PGM5 phosphoglucomutase 5 0.314772
LPXN leupaxin 0.31332
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.312957
ZNF699 zinc finger protein 699 0.311145
UTRN utrophin 0.311145
ZHX2 zinc fingers and homeoboxes 2 0.306805
ORAI2 ORAI calcium release-activated calcium modulator 2 0.305361
GAS6 growth arrest-specific 6 0.303198
SOD3 superoxide dismutase 3, extracellular 0.302118
MAP2K3 mitogen-activated protein kinase kinase 3 0.299601
UTS2 urotensin 2 0.298883
AHSG alpha-2-HS-glycoprotein 0.298883
CD44 CD44 molecule (Indian blood group) 0.297089
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 0.294939
FHOD1 formin homology 2 domain containing 1 0.293866
ARHGAP35 Rho GTPase activating protein 35 0.293866
SCPEP1 serine carboxypeptidase 1 0.289582
TIMP3 TIMP metallopeptidase inhibitor 3 0.289226
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 0.286381
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.284962
BANP BTG3 associated nuclear protein 0.283545
SMOC2 SPARC related modular calcium binding 2 0.283191
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.276846
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.274744
TRAF3 TNF receptor-associated factor 3 0.274744
CSRP2 cysteine and glycine-rich protein 2 0.271604
AXL AXL receptor tyrosine kinase 0.271604
RYR1 ryanodine receptor 1 (skeletal) 0.269867
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 0.269174
PLN phospholamban 0.267791
CASS4 Cas scaffolding protein family member 4 0.267791
NDRG4 NDRG family member 4 0.266069
IGFBP7 insulin-like growth factor binding protein 7 0.264696
COL1A2 collagen, type I, alpha 2 0.262986
CDC14A cell division cycle 14A 0.261964
NPB neuropeptide B 0.256234
APOA1 apolipoprotein A-I 0.25457
MFAP5 microfibrillar associated protein 5 0.254239
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.252261
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.251606
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.250627
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.249977
SPEG SPEG complex locus 0.249329
SMAD7 SMAD family member 7 0.249329
DNM2 dynamin 2 0.24804
GPX4 glutathione peroxidase 4 0.247399
NQO1 NAD(P)H dehydrogenase, quinone 1 0.247079
SMAD2 SMAD family member 2 0.247079
MYB v-myb avian myeloblastosis viral oncogene homolog 0.24676
BAX BCL2-associated X protein 0.245807
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.245491
CARD8 caspase recruitment domain family, member 8 0.245491
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.245491
PTH parathyroid hormone 0.242983
PRAC1 prostate cancer susceptibility candidate 1 0.241132
NT5E 5'-nucleotidase, ecto (CD73) 0.239913
HRAS Harvey rat sarcoma viral oncogene homolog 0.239007
MYLK3 myosin light chain kinase 3 0.237216
HAS1 hyaluronan synthase 1 0.234016
TFPI2 tissue factor pathway inhibitor 2 0.232317
RYR3 ryanodine receptor 3 0.232317
KDR kinase insert domain receptor 0.232039
COL9A3 collagen, type IX, alpha 3 0.232039
EGFR epidermal growth factor receptor 0.23011
GSS glutathione synthetase 0.229839
THBS2 thrombospondin 2 0.228234
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.227707
MEOX1 mesenchyme homeobox 1 0.225395
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.223662
HSPA4 heat shock 70kDa protein 4 0.219485
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.217762
COL9A2 collagen, type IX, alpha 2 0.216325
FGF13 fibroblast growth factor 13 0.214388
PTK2B protein tyrosine kinase 2 beta 0.214017
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.213833
ADRA1D adrenoceptor alpha 1D 0.213471
PTK2 protein tyrosine kinase 2 0.213471
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.212761
GPX5 glutathione peroxidase 5 0.212413