antigen processing and presentation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. (Gene Ontology, GO_0019882)
External Link http://amigo.geneontology.org/amigo/term/GO:0019882
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Genes

217 genes participating in the antigen processing and presentation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACE angiotensin I converting enzyme
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
AP1M1 adaptor-related protein complex 1, mu 1 subunit
AP1M2 adaptor-related protein complex 1, mu 2 subunit
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
ARF1 ADP-ribosylation factor 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B2M beta-2-microglobulin
BCAP31 B-cell receptor-associated protein 31
BLMH bleomycin hydrolase
CALR calreticulin
CANX calnexin
CD1A CD1a molecule
CD1B CD1b molecule
CD1C CD1c molecule
CD1D CD1d molecule
CD1E CD1e molecule
CD207 CD207 molecule, langerin
CD209 CD209 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD8A CD8a molecule
CENPE centromere protein E, 312kDa
CLEC4M C-type lectin domain family 4, member M
CLTA clathrin, light chain A
CLTC clathrin, heavy chain (Hc)
CTSD cathepsin D
CTSE cathepsin E
CTSF cathepsin F
CTSH cathepsin H
CTSL cathepsin L
CTSS cathepsin S
CTSV cathepsin V
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
DCTN1 dynactin 1
DCTN2 dynactin 2 (p50)
DCTN3 dynactin 3 (p22)
DCTN4 dynactin 4 (p62)
DCTN5 dynactin 5 (p25)
DCTN6 dynactin 6
DNM2 dynamin 2
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
DYNLL1 dynein, light chain, LC8-type 1
DYNLL2 dynein, light chain, LC8-type 2
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
HFE hemochromatosis
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
ICAM1 intercellular adhesion molecule 1
IFI30 interferon, gamma-inducible protein 30
IFNG interferon, gamma
ITGAV integrin, alpha V
ITGB5 integrin, beta 5
KIF11 kinesin family member 11
KIF15 kinesin family member 15
KIF18A kinesin family member 18A
KIF22 kinesin family member 22
KIF23 kinesin family member 23
KIF26A kinesin family member 26A
KIF2A kinesin heavy chain member 2A
KIF2B kinesin family member 2B
KIF2C kinesin family member 2C
KIF3A kinesin family member 3A
KIF3B kinesin family member 3B
KIF3C kinesin family member 3C
KIF4A kinesin family member 4A
KIF4B kinesin family member 4B
KIF5A kinesin family member 5A
KIFAP3 kinesin-associated protein 3
KLC1 kinesin light chain 1
KLC2 kinesin light chain 2
LGMN legumain
LNPEP leucyl/cystinyl aminopeptidase
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MR1 major histocompatibility complex, class I-related
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NPEPPS aminopeptidase puromycin sensitive
OSBPL1A oxysterol binding protein-like 1A
PDIA3 protein disulfide isomerase family A, member 3
PROCR protein C receptor, endothelial
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
RAB10 RAB10, member RAS oncogene family
RAB27A RAB27A, member RAS oncogene family
RAB32 RAB32, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RAB34 RAB34, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAB3B RAB3B, member RAS oncogene family
RAB3C RAB3C, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RACGAP1 Rac GTPase activating protein 1
RAET1E retinoic acid early transcript 1E
RAET1G retinoic acid early transcript 1G
RAET1L retinoic acid early transcript 1L
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFTN1 raftlin, lipid raft linker 1
RILP Rab interacting lysosomal protein
RPS27A ribosomal protein S27a
SAR1B secretion associated, Ras related GTPase 1B
SEC13 SEC13 homolog (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24A SEC24 family member A
SEC24B SEC24 family member B
SEC24C SEC24 family member C
SEC24D SEC24 family member D
SEC31A SEC31 homolog A (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEC61B Sec61 beta subunit
SEC61G Sec61 gamma subunit
SH3GL2 SH3-domain GRB2-like 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SPTBN2 spectrin, beta, non-erythrocytic 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TPP2 tripeptidyl peptidase II
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2A ubiquitin-conjugating enzyme E2A
ULBP1 UL16 binding protein 1
ULBP2 UL16 binding protein 2
ULBP3 UL16 binding protein 3
UNC93B1 unc-93 homolog B1 (C. elegans)