anaplastic thyroid cancer cell line Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Cells to a more primitive or undifferentiated form of thyroid cancer. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003209)
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Genes

267 proteins co-occuring with the tissue anaplastic thyroid cancer cell line in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
TRAF3IP2 TRAF3 interacting protein 2 2.17396
RFC2 replication factor C (activator 1) 2, 40kDa 1.87339
IL17A interleukin 17A 1.77228
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) 1.74974
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.68155
TPCN1 two pore segment channel 1 1.60663
TMEM184C transmembrane protein 184C 1.49632
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 1.37636
IL17RA interleukin 17 receptor A 1.37453
IL17RC interleukin 17 receptor C 1.37408
PRPF6 pre-mRNA processing factor 6 1.3686
TRAF5 TNF receptor-associated factor 5 1.36723
IL17RB interleukin 17 receptor B 1.35359
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 1.32551
ADAT2 adenosine deaminase, tRNA-specific 2 1.28412
PAX8 paired box 8 1.26486
CDC40 cell division cycle 40 1.21001
TMA7 translation machinery associated 7 homolog (S. cerevisiae) 1.18734
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 1.15495
PGK1 phosphoglycerate kinase 1 1.15141
PCF11 PCF11 cleavage and polyadenylation factor subunit 1.08104
PARK2 parkin RBR E3 ubiquitin protein ligase 1.07706
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 1.07618
RPL41 ribosomal protein L41 1.07265
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 1.03609
PRPF18 pre-mRNA processing factor 18 0.992379
DUOXA2 dual oxidase maturation factor 2 0.986294
RPL31 ribosomal protein L31 0.974149
TUB tubby bipartite transcription factor 0.940495
USP25 ubiquitin specific peptidase 25 0.931479
IL17C interleukin 17C 0.924623
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 0.91052
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 0.906682
RAB1A RAB1A, member RAS oncogene family 0.904978
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.899445
EXOSC5 exosome component 5 0.88671
TCP11 t-complex 11, testis-specific 0.885862
PABPC1 poly(A) binding protein, cytoplasmic 1 0.870639
NKAP NFKB activating protein 0.869794
RPL30 ribosomal protein L30 0.868529
YEATS4 YEATS domain containing 4 0.85547
PLS1 plastin 1 0.854209
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.846644
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.831547
TRAF3 TNF receptor-associated factor 3 0.818994
SLC26A4 solute carrier family 26 (anion exchanger), member 4 0.814397
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.790628
RBM23 RNA binding motif protein 23 0.788964
GUSB glucuronidase, beta 0.786052
IL17RE interleukin 17 receptor E 0.784804
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.783141
IL17RD interleukin 17 receptor D 0.755777
IL25 interleukin 25 0.755364
RPL10 ribosomal protein L10 0.750405
EEF1B2 eukaryotic translation elongation factor 1 beta 2 0.745864
CBS cystathionine-beta-synthase 0.743801
EEF2 eukaryotic translation elongation factor 2 0.74174
EIF4A3 eukaryotic translation initiation factor 4A3 0.739266
DACT2 dishevelled-binding antagonist of beta-catenin 2 0.726918
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.725274
TPM1 tropomyosin 1 (alpha) 0.714189
PDCL3 phosducin-like 3 0.695763
FGF12 fibroblast growth factor 12 0.695354
EXOSC8 exosome component 8 0.680656
ADGRE5 adhesion G protein-coupled receptor E5 0.670471
RPL3 ribosomal protein L3 0.661523
CD248 CD248 molecule, endosialin 0.65543
ARF4 ADP-ribosylation factor 4 0.648532
PRPF3 pre-mRNA processing factor 3 0.641238
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 0.631931
TSHR thyroid stimulating hormone receptor 0.630718
PRPF19 pre-mRNA processing factor 19 0.625465
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.614167
IL17F interleukin 17F 0.603295
NKX2-1 NK2 homeobox 1 0.594451
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.588031
EIF5 eukaryotic translation initiation factor 5 0.586427
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.585224
ERCC3 excision repair cross-complementation group 3 0.578016
UBP1 upstream binding protein 1 (LBP-1a) 0.576015
ARF1 ADP-ribosylation factor 1 0.574416
CD40 CD40 molecule, TNF receptor superfamily member 5 0.567227
TG thyroglobulin 0.558059
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 0.554478
EXOC3 exocyst complex component 3 0.552888
OXR1 oxidation resistance 1 0.542963
KAT7 K(lysine) acetyltransferase 7 0.538604
RXRG retinoid X receptor, gamma 0.53267
KRT84 keratin 84, type II 0.531879
MIR25 microRNA 25 0.529903
SUMF2 sulfatase modifying factor 2 0.527534
RPL29 ribosomal protein L29 0.527139
NBN nibrin 0.51453
RET ret proto-oncogene 0.512957
CDC7 cell division cycle 7 0.503141
RIMS1 regulating synaptic membrane exocytosis 1 0.499223
TP53 tumor protein p53 0.494918
PTCH1 patched 1 0.489838
CCND1 cyclin D1 0.481648
EEF1A1P6 eukaryotic translation elongation factor 1 alpha 1 pseudogene 6 0.478534
CD40LG CD40 ligand 0.4634
TRAF4 TNF receptor-associated factor 4 0.459918
DEFB4A defensin, beta 4A 0.454126
PCCA propionyl CoA carboxylase, alpha polypeptide 0.449116
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.440274
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.436822
TPI1 triosephosphate isomerase 1 0.434523
MIR19A microRNA 19a 0.429547
DUSP5 dual specificity phosphatase 5 0.425726
SCRT1 scratch family zinc finger 1 0.423818
UBE2N ubiquitin-conjugating enzyme E2N 0.423818
CARD9 caspase recruitment domain family, member 9 0.41848
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.416195
TPM3 tropomyosin 3 0.414293
MAPK9 mitogen-activated protein kinase 9 0.404418
SCGB2A2 secretoglobin, family 2A, member 2 0.40328
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.399114
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.396087
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.395709
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.393442
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.388912
TLR10 toll-like receptor 10 0.38439
YY1 YY1 transcription factor 0.367502
CAPN1 calpain 1, (mu/I) large subunit 0.36302
HNF1B HNF1 homeobox B 0.360782
LGALS3 lectin, galactoside-binding, soluble, 3 0.359664
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.351114
SNORA29 small nucleolar RNA, H/ACA box 29 0.34926
GSK3B glycogen synthase kinase 3 beta 0.348889
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.348519
VCAM1 vascular cell adhesion molecule 1 0.345558
FFAR4 free fatty acid receptor 4 0.340019
CD4 CD4 molecule 0.339282
CNR2 cannabinoid receptor 2 (macrophage) 0.335233
RPL13A ribosomal protein L13a 0.333763
TNF tumor necrosis factor 0.330094
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.325335
DVL2 dishevelled segment polarity protein 2 0.32132
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.320591
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 0.320227
TMSB10 thymosin beta 10 0.317679
MAGEA4 melanoma antigen family A4 0.31187
S100A4 S100 calcium binding protein A4 0.301758
SNED1 sushi, nidogen and EGF-like domains 1 0.301398
PTPRJ protein tyrosine phosphatase, receptor type, J 0.29996
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.293151
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.292079
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.287447
CDC42 cell division cycle 42 0.286381
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.284962
TXNL1 thioredoxin-like 1 0.284253
IGBP1 immunoglobulin (CD79A) binding protein 1 0.284253
OR10A4 olfactory receptor, family 10, subfamily A, member 4 0.278251
EPS15 epidermal growth factor receptor pathway substrate 15 0.274394
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.274045
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.270909
GHSR growth hormone secretagogue receptor 0.260945
FLOT1 flotillin 1 0.260606
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.260267
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.25858
PGAM2 phosphoglycerate mutase 2 (muscle) 0.254239
FANCD2 Fanconi anemia, complementation group D2 0.251934
SNAI1 snail family zinc finger 1 0.24804
IRAK4 interleukin-1 receptor-associated kinase 4 0.247719
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.24486
HSPB1 heat shock 27kDa protein 1 0.243294
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.242672
MAGEA1 melanoma antigen family A1 0.242054
DUSP6 dual specificity phosphatase 6 0.241746
CD44 CD44 molecule (Indian blood group) 0.241438
VIM vimentin 0.240216
PGAM1 phosphoglycerate mutase 1 (brain) 0.235457
RAD50 RAD50 homolog (S. cerevisiae) 0.232881
CUL1 cullin 1 0.230931
CGB7 chorionic gonadotropin, beta polypeptide 7 0.229839
BPGM 2,3-bisphosphoglycerate mutase 0.229568
AGER advanced glycosylation end product-specific receptor 0.228764
BCL3 B-cell CLL/lymphoma 3 0.228764
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.228764
RPSA ribosomal protein SA 0.228234
CGB5 chorionic gonadotropin, beta polypeptide 5 0.227186
MMP2 matrix metallopeptidase 2 0.225144
S1PR3 sphingosine-1-phosphate receptor 3 0.219485
CGB chorionic gonadotropin, beta polypeptide 0.217346
CGB8 chorionic gonadotropin, beta polypeptide 8 0.21673
RORC RAR-related orphan receptor C 0.216126
PLAU plasminogen activator, urokinase 0.170841
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.169811
CD276 CD276 molecule 0.166637
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.162263
FAT1 FAT atypical cadherin 1 0.161304
KLF4 Kruppel-like factor 4 (gut) 0.156174
SOX2 SRY (sex determining region Y)-box 2 0.152109
NANOG Nanog homeobox 0.15054
MAGEA3 melanoma antigen family A3 0.149115
FOXP3 forkhead box P3 0.148142
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.1459
TIMP3 TIMP metallopeptidase inhibitor 3 0.142606
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.141283
IL1A interleukin 1, alpha 0.140857
CCR4 chemokine (C-C motif) receptor 4 0.138179
S1PR2 sphingosine-1-phosphate receptor 2 0.136831
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.136337
EGFR epidermal growth factor receptor 0.134877
THRB thyroid hormone receptor, beta 0.134366
VEGFA vascular endothelial growth factor A 0.133935
MIR17 microRNA 17 0.133426
PLD2 phospholipase D2 0.131783
PTEN phosphatase and tensin homolog 0.131579
IGFBP6 insulin-like growth factor binding protein 6 0.131087
CCNA2 cyclin A2 0.130391
CCNB1 cyclin B1 0.129354
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.126904
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.126217
KAT2B K(lysine) acetyltransferase 2B 0.126174
AXIN1 axin 1 0.124698
HK2 hexokinase 2 0.124034
THY1 Thy-1 cell surface antigen 0.123901
IL6 interleukin 6 0.121851
TXNRD2 thioredoxin reductase 2 0.121806
HNF4A hepatocyte nuclear factor 4, alpha 0.121761
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.121087
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.12086
ESR2 estrogen receptor 2 (ER beta) 0.119991
S1PR1 sphingosine-1-phosphate receptor 1 0.119534
HDAC9 histone deacetylase 9 0.118334
TIMP2 TIMP metallopeptidase inhibitor 2 0.118056
GPER1 G protein-coupled estrogen receptor 1 0.117453
MMP9 matrix metallopeptidase 9 0.116939
CDC25C cell division cycle 25C 0.116044
CCND3 cyclin D3 0.114527
ACTB actin, beta 0.112465
GFI1 growth factor independent 1 transcription repressor 0.112465
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.112223
ZEB1 zinc finger E-box binding homeobox 1 0.111933
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.111547
LCN2 lipocalin 2 0.111209
IL2RA interleukin 2 receptor, alpha 0.111062
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.110866
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.11067
ACTG1 actin gamma 1 0.110082
TBK1 TANK-binding kinase 1 0.109495
IL1B interleukin 1, beta 0.109398
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.109251
RPS27A ribosomal protein S27a 0.108905
SKAP2 src kinase associated phosphoprotein 2 0.108608
SKP1 S-phase kinase-associated protein 1 0.107421
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.107075
CDK6 cyclin-dependent kinase 6 0.105875
HSPG2 heparan sulfate proteoglycan 2 0.105875
MMP1 matrix metallopeptidase 1 0.105575
PHF1 PHD finger protein 1 0.105475
HMGA2 high mobility group AT-hook 2 0.105375
DNTT DNA nucleotidylexotransferase 0.105325
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 0.105176
FADD Fas (TNFRSF6)-associated via death domain 0.103714
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.103714
CXCL10 chemokine (C-X-C motif) ligand 10 0.102908
MCM7 minichromosome maintenance complex component 7 0.102806
PLCG1 phospholipase C, gamma 1 0.102806
WAS Wiskott-Aldrich syndrome 0.102551
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 0.101737
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.101687
PARP1 poly (ADP-ribose) polymerase 1 0.100874
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.100824
LPO lactoperoxidase 0.100516
CD99 CD99 molecule 0.100413