A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B. (Gene Ontology, GO_0005680)
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19 proteins localized to the anaphase-promoting complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.