anaphase-promoting complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B. (Gene Ontology, GO_0005680)
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19 proteins localized to the anaphase-promoting complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ANAPC1 anaphase promoting complex subunit 1 0.663342
ANAPC11 anaphase promoting complex subunit 11 0.663342
ANAPC16 anaphase promoting complex subunit 16 0.663342
ANAPC15 anaphase promoting complex subunit 15 0.663342
CUL7 cullin 7 0.663342
CDC16 cell division cycle 16 0.663342
UBE2S ubiquitin-conjugating enzyme E2S 0.663342
UBE2C ubiquitin-conjugating enzyme E2C 0.663342
ANAPC13 anaphase promoting complex subunit 13 0.663342
CDC23 cell division cycle 23 0.663342
ANAPC2 anaphase promoting complex subunit 2 0.663342
ANAPC5 anaphase promoting complex subunit 5 0.663342
ANAPC4 anaphase promoting complex subunit 4 0.663342
ANAPC7 anaphase promoting complex subunit 7 0.663342
CDC27 cell division cycle 27 0.663342
CDC26 cell division cycle 26 0.663342
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.663342
ANAPC10 anaphase promoting complex subunit 10 0.663342
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.237908