ampicillin-5408 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the ampicillin-5408 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADGRE3 adhesion G protein-coupled receptor E3
ADORA1 adenosine A1 receptor
ALX4 ALX homeobox 4
ARID4B AT rich interactive domain 4B (RBP1-like)
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C11ORF63 chromosome 11 open reading frame 63
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CD7 CD7 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CFHR4 complement factor H-related 4
CLEC3B C-type lectin domain family 3, member B
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNR2 cannabinoid receptor 2 (macrophage)
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
CTGF connective tissue growth factor
CXCL13 chemokine (C-X-C motif) ligand 13
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DCC DCC netrin 1 receptor
DNASE1L3 deoxyribonuclease I-like 3
ELAC2 elaC ribonuclease Z 2
ENO3 enolase 3 (beta, muscle)
FANCA Fanconi anemia, complementation group A
FBXL7 F-box and leucine-rich repeat protein 7
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FLOT1 flotillin 1
FMOD fibromodulin
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GAS7 growth arrest-specific 7
GK glycerol kinase
GM2A GM2 ganglioside activator
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR27 G protein-coupled receptor 27
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GREM2 gremlin 2, DAN family BMP antagonist
GSPT1 G1 to S phase transition 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HCG4 HLA complex group 4 (non-protein coding)
HFE hemochromatosis
HOXD1 homeobox D1
IDS iduronate 2-sulfatase
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGFBP5 insulin-like growth factor binding protein 5
IGKV4-1 immunoglobulin kappa variable 4-1
IMPG2 interphotoreceptor matrix proteoglycan 2
INHBA inhibin, beta A
IRF4 interferon regulatory factor 4
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLHL22 kelch-like family member 22
LDLR low density lipoprotein receptor
LRP12 low density lipoprotein receptor-related protein 12
MAOB monoamine oxidase B
MAPK8 mitogen-activated protein kinase 8
MCTP1 multiple C2 domains, transmembrane 1
MET MET proto-oncogene, receptor tyrosine kinase
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MOBP myelin-associated oligodendrocyte basic protein
MROH7 maestro heat-like repeat family member 7
MTAP methylthioadenosine phosphorylase
NPR3 natriuretic peptide receptor 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OMG oligodendrocyte myelin glycoprotein
ONECUT2 one cut homeobox 2
OXCT2 3-oxoacid CoA transferase 2
PCDHB12 protocadherin beta 12
PEG3 paternally expressed 3
PIP prolactin-induced protein
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLK4 polo-like kinase 4
PMFBP1 polyamine modulated factor 1 binding protein 1
POU4F1 POU class 4 homeobox 1
PRB1 proline-rich protein BstNI subfamily 1
RERE arginine-glutamic acid dipeptide (RE) repeats
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RGS4 regulator of G-protein signaling 4
RPA4 replication protein A4, 30kDa
RPL23AP53 ribosomal protein L23a pseudogene 53
RPL35A ribosomal protein L35a
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLMO1 slowmo homolog 1 (Drosophila)
SRRT serrate, RNA effector molecule
SUGP1 SURP and G patch domain containing 1
TREX1 three prime repair exonuclease 1
TRIM21 tripartite motif containing 21
VPREB3 pre-B lymphocyte 3
WNT16 wingless-type MMTV integration site family, member 16
ZNF702P zinc finger protein 702, pseudogene

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACTL8 actin-like 8
ACVR2B activin A receptor, type IIB
ADAP2 ArfGAP with dual PH domains 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATAD5 ATPase family, AAA domain containing 5
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C1QTNF3 C1q and tumor necrosis factor related protein 3
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CALCOCO1 calcium binding and coiled-coil domain 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC88C coiled-coil domain containing 88C
CD3EAP CD3e molecule, epsilon associated protein
CD79B CD79b molecule, immunoglobulin-associated beta
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHKB choline kinase beta
CRY2 cryptochrome circadian clock 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTSF cathepsin F
CUZD1 CUB and zona pellucida-like domains 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DUSP13 dual specificity phosphatase 13
EDC4 enhancer of mRNA decapping 4
EFNA3 ephrin-A3
ELMO3 engulfment and cell motility 3
F2R coagulation factor II (thrombin) receptor
FAM212B family with sequence similarity 212, member B
FICD FIC domain containing
FLCN folliculin
GALT galactose-1-phosphate uridylyltransferase
GAS2 growth arrest-specific 2
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNL1 guanine nucleotide binding protein-like 1
GRTP1 growth hormone regulated TBC protein 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC5 histone deacetylase 5
HIST1H1E histone cluster 1, H1e
HOXC10 homeobox C10
HOXC5 homeobox C5
IFT22 intraflagellar transport 22
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF1 interferon regulatory factor 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCTD15 potassium channel tetramerization domain containing 15
KIF13A kinesin family member 13A
KLF11 Kruppel-like factor 11
KLF2 Kruppel-like factor 2
KRT15 keratin 15, type I
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED24 mediator complex subunit 24
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MXD3 MAX dimerization protein 3
NDE1 nudE neurodevelopment protein 1
NIPAL2 NIPA-like domain containing 2
NME5 NME/NM23 family member 5
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHB3 protocadherin beta 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
RAB3A RAB3A, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RUNDC3B RUN domain containing 3B
SAYSD1 SAYSVFN motif domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SETD1A SET domain containing 1A
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLIT2 slit homolog 2 (Drosophila)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNHG3 small nucleolar RNA host gene 3
SPATA7 spermatogenesis associated 7
SPINK5 serine peptidase inhibitor, Kazal type 5
ST5 suppression of tumorigenicity 5
SUN2 Sad1 and UNC84 domain containing 2
TBC1D17 TBC1 domain family, member 17
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCHH trichohyalin
THRAP3 thyroid hormone receptor associated protein 3
TMEM212 transmembrane protein 212
TOLLIP toll interacting protein
TPK1 thiamin pyrophosphokinase 1
TRABD TraB domain containing
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTC30A tetratricopeptide repeat domain 30A
TUBA3C tubulin, alpha 3c
UNC93B1 unc-93 homolog B1 (C. elegans)
VLDLR very low density lipoprotein receptor
ZFP69B ZFP69 zinc finger protein B
ZNF227 zinc finger protein 227
ZNF282 zinc finger protein 282