alzheimer Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

404 genes co-occuring with the biological term alzheimer in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACHE acetylcholinesterase (Yt blood group)
ACO1 aconitase 1, soluble
ADAM10 ADAM metallopeptidase domain 10
ADAM9 ADAM metallopeptidase domain 9
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRBK1 adrenergic, beta, receptor kinase 1
AGER advanced glycosylation end product-specific receptor
AGTR2 angiotensin II receptor, type 2
AHSG alpha-2-HS-glycoprotein
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALPL alkaline phosphatase, liver/bone/kidney
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT4 angiopoietin 4
ANK1 ankyrin 1, erythrocytic
ANXA4 annexin A4
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APCS amyloid P component, serum
APH1A APH1A gamma secretase subunit
APLP2 amyloid beta (A4) precursor-like protein 2
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOC1 apolipoprotein C-I
APOD apolipoprotein D
APOE apolipoprotein E
APOM apolipoprotein M
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
ARC activity-regulated cytoskeleton-associated protein
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATF2 activating transcription factor 2
ATF4 activating transcription factor 4
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
ATP7B ATPase, Cu++ transporting, beta polypeptide
BACE1 beta-site APP-cleaving enzyme 1
BACE2 beta-site APP-cleaving enzyme 2
BAX BCL2-associated X protein
BCHE butyrylcholinesterase
BCL2 B-cell CLL/lymphoma 2
BCL2L2 BCL2-like 2
BCR breakpoint cluster region
BCYRN1 brain cytoplasmic RNA 1
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BIN1 bridging integrator 1
BLMH bleomycin hydrolase
BLVRA biliverdin reductase A
BMP4 bone morphogenetic protein 4
BRCA1 breast cancer 1, early onset
BST1 bone marrow stromal cell antigen 1
CA2 carbonic anhydrase II
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CALHM1 calcium homeostasis modulator 1
CALHM2 calcium homeostasis modulator 2
CALHM3 calcium homeostasis modulator 3
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK1 calcium/calmodulin-dependent protein kinase I
CAPN1 calpain 1, (mu/I) large subunit
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CBS cystathionine-beta-synthase
CCL2 chemokine (C-C motif) ligand 2
CCR2 chemokine (C-C motif) receptor 2
CD14 CD14 molecule
CD33 CD33 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK1 cyclin-dependent kinase 1
CDK11B cyclin-dependent kinase 11B
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CENPJ centromere protein J
CETP cholesteryl ester transfer protein, plasma
CFH complement factor H
CHAT choline O-acetyltransferase
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CIAPIN1 cytokine induced apoptosis inhibitor 1
CLSTN3 calsyntenin 3
CLU clusterin
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CNTN5 contactin 5
COL18A1 collagen, type XVIII, alpha 1
COL25A1 collagen, type XXV, alpha 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COMT catechol-O-methyltransferase
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CREB1 cAMP responsive element binding protein 1
CRP C-reactive protein, pentraxin-related
CSNK1D casein kinase 1, delta
CST3 cystatin C
CTCF CCCTC-binding factor (zinc finger protein)
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTSB cathepsin B
CTSD cathepsin D
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DAPK1 death-associated protein kinase 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNM1L dynamin 1-like
DNM2 dynamin 2
DOCK3 dedicator of cytokinesis 3
DPYSL2 dihydropyrimidinase-like 2
DRD3 dopamine receptor D3
DRD5 dopamine receptor D5
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
E2F1 E2F transcription factor 1
ECE1 endothelin converting enzyme 1
EEF2 eukaryotic translation elongation factor 2
EEF2K eukaryotic elongation factor 2 kinase
EGR1 early growth response 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ENO1 enolase 1, (alpha)
EPOR erythropoietin receptor
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FABP3 fatty acid binding protein 3, muscle and heart
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FRMD6 FERM domain containing 6
FTO fat mass and obesity associated
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB2 GRB2-associated binding protein 2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GAL galanin/GMAP prepropeptide
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GAS7 growth arrest-specific 7
GBA glucosidase, beta, acid
GDNF glial cell derived neurotrophic factor
GFAP glial fibrillary acidic protein
GH1 growth hormone 1
GMFB glia maturation factor, beta
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GOLM1 golgi membrane protein 1
GPHN gephyrin
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRN granulin
GSK3B glycogen synthase kinase 3 beta
GSTM3 glutathione S-transferase mu 3 (brain)
GSTO1 glutathione S-transferase omega 1
HACD1 3-hydroxyacyl-CoA dehydratase 1
HDAC6 histone deacetylase 6
HFE hemochromatosis
HLA-A major histocompatibility complex, class I, A
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMOX1 heme oxygenase 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HPCAL1 hippocalcin-like 1
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IDE insulin-degrading enzyme
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2R insulin-like growth factor 2 receptor
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL23R interleukin 23 receptor
IL33 interleukin 33
IL6 interleukin 6
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITM2B integral membrane protein 2B
KALRN kalirin, RhoGEF kinase
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KEAP1 kelch-like ECH-associated protein 1
KIAA1462 KIAA1462
KLK10 kallikrein-related peptidase 10
KLK7 kallikrein-related peptidase 7
LAMA1 laminin, alpha 1
LAMC1 laminin, gamma 1 (formerly LAMB2)
LEP leptin
LEPR leptin receptor
LGMN legumain
LRP1 low density lipoprotein receptor-related protein 1
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRK2 leucine-rich repeat kinase 2
LRRTM3 leucine rich repeat transmembrane neuronal 3
MAOB monoamine oxidase B
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MARK1 MAP/microtubule affinity-regulating kinase 1
MCPH1 microcephalin 1
MEOX2 mesenchyme homeobox 2
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MIR144 microRNA 144
MIR146A microRNA 146a
MIR206 microRNA 206
MIR34C microRNA 34c
MIR590 microRNA 590
MME membrane metallo-endopeptidase
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MSI1 musashi RNA-binding protein 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NAAA N-acylethanolamine acid amidase
NACA nascent polypeptide-associated complex alpha subunit
NCAM1 neural cell adhesion molecule 1
NCSTN nicastrin
NDRG2 NDRG family member 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEFH neurofilament, heavy polypeptide
NEFM neurofilament, medium polypeptide
NES nestin
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGB neuroglobin
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NLRP1 NLR family, pyrin domain containing 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NME2 NME/NM23 nucleoside diphosphate kinase 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPB natriuretic peptide B
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRD1 nardilysin (N-arginine dibasic convertase)
NRG1 neuregulin 1
NRG3 neuregulin 3
NRGN neurogranin (protein kinase C substrate, RC3)
NSUN4 NOP2/Sun domain family, member 4
NTF3 neurotrophin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUMB numb homolog (Drosophila)
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARK16 Parkinson disease 16 (susceptibility)
PARK7 parkinson protein 7
PAWR PRKC, apoptosis, WT1, regulator
PCDH11X protocadherin 11 X-linked
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PCSK1 proprotein convertase subtilisin/kexin type 1
PCSK2 proprotein convertase subtilisin/kexin type 2
PCSK9 proprotein convertase subtilisin/kexin type 9
PDIA2 protein disulfide isomerase family A, member 2
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PICALM phosphatidylinositol binding clathrin assembly protein
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G3 phospholipase A2, group III
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
POLG polymerase (DNA directed), gamma
POMC proopiomelanocortin
PON1 paraoxonase 1
PON2 paraoxonase 2
PON3 paraoxonase 3
PPARG peroxisome proliferator-activated receptor gamma
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PRDX3 peroxiredoxin 3
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCD protein kinase C, delta
PRNP prion protein
PSEN1 presenilin 1
PSEN2 presenilin 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGES2 prostaglandin E synthase 2
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
PZP pregnancy-zone protein
QPCT glutaminyl-peptide cyclotransferase
RAB27A RAB27A, member RAS oncogene family
RAB29 RAB29, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RANBP9 RAN binding protein 9
RELN reelin
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RPS3A ribosomal protein S3A
RTN4 reticulon 4
RTN4R reticulon 4 receptor
SCO2 SCO2 cytochrome c oxidase assembly protein
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SIRT3 sirtuin 3
SIRT5 sirtuin 5
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX1 sorting nexin 1
SOD1 superoxide dismutase 1, soluble
SORCS1 sortilin-related VPS10 domain containing receptor 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SP1 Sp1 transcription factor
SPON1 spondin 1, extracellular matrix protein
SPPL2B signal peptide peptidase like 2B
SQSTM1 sequestosome 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SREK1IP1 SREK1-interacting protein 1
SST somatostatin
SSTR4 somatostatin receptor 4
STH saitohin
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STXBP1 syntaxin binding protein 1
SYPL2 synaptophysin-like 2
TAC1 tachykinin, precursor 1
TARDBP TAR DNA binding protein
TDO2 tryptophan 2,3-dioxygenase
TFAM transcription factor A, mitochondrial
TFCP2 transcription factor CP2
TGFB1 transforming growth factor, beta 1
TGM1 transglutaminase 1
TGM2 transglutaminase 2
THRA thyroid hormone receptor, alpha
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMEM106B transmembrane protein 106B
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNMD tenomodulin
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TP53 tumor protein p53
TPI1 triosephosphate isomerase 1
TRAF2 TNF receptor-associated factor 2
TREM2 triggering receptor expressed on myeloid cells 2
TRH thyrotropin-releasing hormone
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TSPAN12 tetraspanin 12
TTR transthyretin
TUBB3 tubulin, beta 3 class III
UBQLN1 ubiquilin 1
UGCG UDP-glucose ceramide glucosyltransferase
UNC5C unc-5 homolog C (C. elegans)
USF1 upstream transcription factor 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VSNL1 visinin-like 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta