alveolar cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Any cell of the walls of the pulmonary alveoli; the term is often limited to alveolar epithelial cells (type I and type II alveolar cells) and alveolar macrophages. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000395)
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Genes

384 proteins co-occuring with the tissue alveolar cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
SFTPC surfactant protein C 2.62812
SFTPB surfactant protein B 2.17765
PROS2P protein S (beta) pseudogene 2.13364
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 2.03214
SFTPD surfactant protein D 1.91174
NKX2-1 NK2 homeobox 1 1.87081
FGF7 fibroblast growth factor 7 1.80514
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 1.55503
MUC1 mucin 1, cell surface associated 1.53047
AQP5 aquaporin 5 1.46355
LPCAT3 lysophosphatidylcholine acyltransferase 3 1.40846
CAT catalase 1.29849
NAPSA napsin A aspartic peptidase 1.29714
SFTPA1 surfactant protein A1 1.26799
SOD2 superoxide dismutase 2, mitochondrial 1.22737
RAB38 RAB38, member RAS oncogene family 1.19311
SFTPA2 surfactant protein A2 1.17314
TNF tumor necrosis factor 1.15008
PCNA proliferating cell nuclear antigen 1.13811
FN1 fibronectin 1 1.1266
TGFB1 transforming growth factor, beta 1 1.1173
CKAP4 cytoskeleton-associated protein 4 1.05193
KRT18 keratin 18, type I 1.01331
DNTT DNA nucleotidylexotransferase 0.980217
IL1B interleukin 1, beta 0.968523
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.960744
ALB albumin 0.942215
CPM carboxypeptidase M 0.933624
FGF10 fibroblast growth factor 10 0.928478
ALPP alkaline phosphatase, placental 0.915215
PDPN podoplanin 0.915215
ALPPL2 alkaline phosphatase, placental-like 2 0.905831
ALPL alkaline phosphatase, liver/bone/kidney 0.904978
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.901147
DNAH8 dynein, axonemal, heavy chain 8 0.899871
SFTA3 surfactant associated 3 0.89902
CHKA choline kinase alpha 0.895195
HPS1 Hermansky-Pudlak syndrome 1 0.881627
CAV1 caveolin 1, caveolae protein, 22kDa 0.881204
PLA2G1B phospholipase A2, group IB (pancreas) 0.876974
ICAM1 intercellular adhesion molecule 1 0.873172
CCL26 chemokine (C-C motif) ligand 26 0.860521
SFTA2 surfactant associated 2 0.847065
GPX1 glutathione peroxidase 1 0.844965
FOXJ1 forkhead box J1 0.838252
TP53 tumor protein p53 0.826104
GPX4 glutathione peroxidase 4 0.820666
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.806882
INTS12 integrator complex subunit 12 0.806047
GPX5 glutathione peroxidase 5 0.80563
CD68 CD68 molecule 0.801876
ANXA7 annexin A7 0.801459
ACE2 angiotensin I converting enzyme 2 0.787299
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.769441
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.769027
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.763226
CSN2 casein beta 0.752057
FOXM1 forkhead box M1 0.751231
CAV2 caveolin 2 0.749166
CXCL8 chemokine (C-X-C motif) ligand 8 0.747927
GSTCD glutathione S-transferase, C-terminal domain containing 0.742564
CCL24 chemokine (C-C motif) ligand 24 0.74174
PTHLH parathyroid hormone-like hormone 0.740503
CCL2 chemokine (C-C motif) ligand 2 0.735971
LYZ lysozyme 0.718292
AGER advanced glycosylation end product-specific receptor 0.712139
BAX BCL2-associated X protein 0.711729
TSPO translocator protein (18kDa) 0.710909
RLIM ring finger protein, LIM domain interacting 0.696989
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.696172
SCNN1G sodium channel, non voltage gated 1 gamma subunit 0.696172
CCL3 chemokine (C-C motif) ligand 3 0.686368
GLB1 galactosidase, beta 1 0.675765
TLR4 toll-like receptor 4 0.668436
FGF1 fibroblast growth factor 1 (acidic) 0.667622
CSN1S1 casein alpha s1 0.662742
IGF1 insulin-like growth factor 1 (somatomedin C) 0.656242
INS insulin 0.65543
POR P450 (cytochrome) oxidoreductase 0.652994
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 0.652994
SOD3 superoxide dismutase 3, extracellular 0.652589
GSR glutathione reductase 0.652183
CCDC59 coiled-coil domain containing 59 0.643669
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.640023
TSC2 tuberous sclerosis 2 0.628293
AQP3 aquaporin 3 (Gill blood group) 0.627889
GPR162 G protein-coupled receptor 162 0.624254
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.621024
KIAA0101 KIAA0101 0.619007
FASLG Fas ligand (TNF superfamily, member 6) 0.61699
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 0.603295
LRP2 low density lipoprotein receptor-related protein 2 0.602088
MED27 mediator complex subunit 27 0.600479
MMP2 matrix metallopeptidase 2 0.597666
ASPH aspartate beta-hydroxylase 0.595656
ARL5A ADP-ribosylation factor-like 5A 0.588431
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.586026
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 0.58322
FOXA1 forkhead box A1 0.58242
MMP12 matrix metallopeptidase 12 0.578816
IFNL1 interferon, lambda 1 0.575616
GGT1 gamma-glutamyltransferase 1 0.566828
LAMP3 lysosomal-associated membrane protein 3 0.565232
HPS4 Hermansky-Pudlak syndrome 4 0.562042
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.561644
GNPAT glyceronephosphate O-acyltransferase 0.561245
IL1A interleukin 1, alpha 0.560847
ACE angiotensin I converting enzyme 0.558059
IL6 interleukin 6 0.557661
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 0.552093
RPS21 ribosomal protein S21 0.550106
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 0.544549
KLHL20 kelch-like family member 20 0.543359
ARL14 ADP-ribosylation factor-like 14 0.539
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.535438
ITGB6 integrin, beta 6 0.533065
CD4 CD4 molecule 0.53267
GPX3 glutathione peroxidase 3 0.530693
AQP4 aquaporin 4 0.527928
RGMB repulsive guidance molecule family member b 0.526744
MPO myeloperoxidase 0.524771
MMP9 matrix metallopeptidase 9 0.523588
CLDN5 claudin 5 0.522011
PLAGL2 pleiomorphic adenoma gene-like 2 0.519253
EGFR epidermal growth factor receptor 0.516891
KRT7 keratin 7, type II 0.51453
FTH1 ferritin, heavy polypeptide 1 0.512171
CLDN18 claudin 18 0.508242
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.507849
DDIT4 DNA-damage-inducible transcript 4 0.505102
HRAS Harvey rat sarcoma viral oncogene homolog 0.50471
DEFB1 defensin, beta 1 0.503926
MMP1 matrix metallopeptidase 1 0.50275
ERRFI1 ERBB receptor feedback inhibitor 1 0.498832
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.495701
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.494918
GSTA1 glutathione S-transferase alpha 1 0.486716
KRT19 keratin 19, type I 0.483986
CLDN4 claudin 4 0.483986
FTL ferritin, light polypeptide 0.482428
AQP1 aquaporin 1 (Colton blood group) 0.48048
ACPP acid phosphatase, prostate 0.478923
TF transferrin 0.475812
PLTP phospholipid transfer protein 0.47348
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.471539
ELF5 E74-like factor 5 (ets domain transcription factor) 0.468048
NGLY1 N-glycanase 1 0.466885
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.463787
STAT5A signal transducer and activator of transcription 5A 0.4634
GSTA3 glutathione S-transferase alpha 3 0.457214
RAB4B RAB4B, member RAS oncogene family 0.457214
GSTA4 glutathione S-transferase alpha 4 0.455284
GSTA2 glutathione S-transferase alpha 2 0.454898
UNC13C unc-13 homolog C (C. elegans) 0.449116
ANXA2 annexin A2 0.447576
CLDN7 claudin 7 0.447192
CTSH cathepsin H 0.445653
KRAS Kirsten rat sarcoma viral oncogene homolog 0.440274
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.432991
FASN fatty acid synthase 0.432608
KRT8 keratin 8, type II 0.431077
PLG plasminogen 0.430695
BMPR1A bone morphogenetic protein receptor, type IA 0.428018
CLDN3 claudin 3 0.426109
PRMT2 protein arginine methyltransferase 2 0.423054
LALBA lactalbumin, alpha- 0.42191
CRTAC1 cartilage acidic protein 1 0.420766
THOP1 thimet oligopeptidase 1 0.419242
CD44 CD44 molecule (Indian blood group) 0.415434
LAMB2 laminin, beta 2 (laminin S) 0.415434
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.414293
CCR3 chemokine (C-C motif) receptor 3 0.413151
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.407832
CRYZ crystallin, zeta (quinone reductase) 0.405555
TSC1 tuberous sclerosis 1 0.40328
VEGFA vascular endothelial growth factor A 0.402523
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.401386
NT5C 5', 3'-nucleotidase, cytosolic 0.393442
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.387781
SLPI secretory leukocyte peptidase inhibitor 0.387027
CA6 carbonic anhydrase VI 0.38552
TMPRSS11D transmembrane protease, serine 11D 0.379123
ABHD2 abhydrolase domain containing 2 0.377245
GSS glutathione synthetase 0.37687
ULK2 unc-51 like autophagy activating kinase 2 0.374993
HSPA4L heat shock 70kDa protein 4-like 0.374243
OCLN occludin 0.374243
PRLR prolactin receptor 0.372369
ANKK1 ankyrin repeat and kinase domain containing 1 0.371619
CXCL10 chemokine (C-X-C motif) ligand 10 0.369747
PPA2 pyrophosphatase (inorganic) 2 0.368624
CD79A CD79a molecule, immunoglobulin-associated alpha 0.368624
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.36825
KRT14 keratin 14, type I 0.367876
CLEC1B C-type lectin domain family 1, member B 0.365633
VCAM1 vascular cell adhesion molecule 1 0.365633
ANXA4 annexin A4 0.365633
GLRX3 glutaredoxin 3 0.364513
PPARG peroxisome proliferator-activated receptor gamma 0.362646
SCP2 sterol carrier protein 2 0.362273
GPX2 glutathione peroxidase 2 0.362273
DCN decorin 0.356314
FOXA2 forkhead box A2 0.356314
HIF3A hypoxia inducible factor 3, alpha subunit 0.354084
FCN3 ficolin (collagen/fibrinogen domain containing) 3 0.351856
NFE2L2 nuclear factor, erythroid 2-like 2 0.34963
SGK1 serum/glucocorticoid regulated kinase 1 0.347408
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 0.347408
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.341863
JUN jun proto-oncogene 0.341495
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.340757
CALCA calcitonin-related polypeptide alpha 0.33965
TJP1 tight junction protein 1 0.339282
NQO1 NAD(P)H dehydrogenase, quinone 1 0.338545
CLDN1 claudin 1 0.338545
GJA1 gap junction protein, alpha 1, 43kDa 0.338177
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.338177
EDN1 endothelin 1 0.338177
HMOX1 heme oxygenase 1 0.336336
FGF2 fibroblast growth factor 2 (basic) 0.334498
NKRF NFKB repressing factor 0.332294
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.330094
IL10 interleukin 10 0.325701
TJP2 tight junction protein 2 0.325335
HMGB1 high mobility group box 1 0.322414
DST dystonin 0.321685
PRDX6 peroxiredoxin 6 0.320227
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.318407
LTF lactotransferrin 0.316588
TIMP2 TIMP metallopeptidase inhibitor 2 0.316224
CXCL2 chemokine (C-X-C motif) ligand 2 0.313683
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.312595
TIMP1 TIMP metallopeptidase inhibitor 1 0.312232
CCL11 chemokine (C-C motif) ligand 11 0.31187
CH25H cholesterol 25-hydroxylase 0.311507
PI3 peptidase inhibitor 3, skin-derived 0.311145
PDGFB platelet-derived growth factor beta polypeptide 0.311145
C3ORF18 chromosome 3 open reading frame 18 0.309697
ANXA5 annexin A5 0.307889
SYP synaptophysin 0.30464
C1S complement component 1, s subcomponent 0.303919
DOK3 docking protein 3 0.303559
TMPRSS2 transmembrane protease, serine 2 0.29996
CD34 CD34 molecule 0.299601
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.298165
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.297447
ANPEP alanyl (membrane) aminopeptidase 0.296013
F8 coagulation factor VIII, procoagulant component 0.293866
SNAP23 synaptosomal-associated protein, 23kDa 0.292793
CDON cell adhesion associated, oncogene regulated 0.292436
LYNX1 Ly6/neurotoxin 1 0.291365
PODXL podocalyxin-like 0.28887
PGR progesterone receptor 0.287447
APOA1 apolipoprotein A-I 0.287092
SCPEP1 serine carboxypeptidase 1 0.281776
BCL2 B-cell CLL/lymphoma 2 0.281776
ECE1 endothelin converting enzyme 1 0.280364
ERN1 endoplasmic reticulum to nucleus signaling 1 0.280012
XBP1 X-box binding protein 1 0.277549
LAMP2 lysosomal-associated membrane protein 2 0.276495
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.276145
HSPA4 heat shock 70kDa protein 4 0.276145
GLTP glycolipid transfer protein 0.273346
ACTB actin, beta 0.271952
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.268137
NFE2L3 nuclear factor, erythroid 2-like 3 0.267791
ANXA1 annexin A1 0.266069
EIF3E eukaryotic translation initiation factor 3, subunit E 0.265381
LRRC38 leucine rich repeat containing 38 0.263327
GRHL2 grainyhead-like 2 (Drosophila) 0.261964
CTSB cathepsin B 0.259929
CNGA1 cyclic nucleotide gated channel alpha 1 0.259591
SCGB3A2 secretoglobin, family 3A, member 2 0.259254
DUOX1 dual oxidase 1 0.25858
ACTG1 actin gamma 1 0.255567
PRF1 perforin 1 (pore forming protein) 0.255234
ELANE elastase, neutrophil expressed 0.254902
ADA adenosine deaminase 0.253578
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.250953
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.250627
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.247399
CCND1 cyclin D1 0.247079
CADM1 cell adhesion molecule 1 0.24676
LEP leptin 0.245491
CAV3 caveolin 3 0.244232
F3 coagulation factor III (thromboplastin, tissue factor) 0.244232
PCYT1B phosphate cytidylyltransferase 1, choline, beta 0.242363
CTSS cathepsin S 0.239913
CTSD cathepsin D 0.238406
CPVL carboxypeptidase, vitellogenic-like 0.237216
FOXF2 forkhead box F2 0.236627
GCLC glutamate-cysteine ligase, catalytic subunit 0.23604
NCK2 NCK adaptor protein 2 0.235457
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.234878
ENO2 enolase 2 (gamma, neuronal) 0.234016
NOS3 nitric oxide synthase 3 (endothelial cell) 0.234016
TICAM2 toll-like receptor adaptor molecule 2 0.233731
CXCL5 chemokine (C-X-C motif) ligand 5 0.232599
DDIT3 DNA-damage-inducible transcript 3 0.232599
TFRC transferrin receptor 0.231206
FGFR2 fibroblast growth factor receptor 2 0.228234
FLOT1 flotillin 1 0.227707
FLCN folliculin 0.226926
PTPRS protein tyrosine phosphatase, receptor type, S 0.225395
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.225395
KAT8 K(lysine) acetyltransferase 8 0.224645
GSTM4 glutathione S-transferase mu 4 0.223419
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.223177
FBP1 fructose-1,6-bisphosphatase 1 0.222938
ECI1 enoyl-CoA delta isomerase 1 0.222699
SPTB spectrin, beta, erythrocytic 0.221755
SREBF1 sterol regulatory element binding transcription factor 1 0.221291
ANXA8 annexin A8 0.220378
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 0.220152
PGC progastricsin (pepsinogen C) 0.21883
ESRP1 epithelial splicing regulatory protein 1 0.218398
CCL5 chemokine (C-C motif) ligand 5 0.218186
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.217554
NPC2 Niemann-Pick disease, type C2 0.217139
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 0.216126
MDK midkine (neurite growth-promoting factor 2) 0.216126
QSOX1 quiescin Q6 sulfhydryl oxidase 1 0.215147
STX2 syntaxin 2 0.215147
MX2 MX dynamin-like GTPase 2 0.214765
GLRX2 glutaredoxin 2 0.214765
CTSE cathepsin E 0.214202
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.213833
DCLK3 doublecortin-like kinase 3 0.213291
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.213112
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.20886
NOTCH4 notch 4 0.204368
NSF N-ethylmaleimide-sensitive factor 0.191898
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.191819
TM4SF1 transmembrane 4 L six family member 1 0.19138
SETD7 SET domain containing (lysine methyltransferase) 7 0.191368
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 0.191308
MYL9 myosin, light chain 9, regulatory 0.191237
ACRBP acrosin binding protein 0.190796
G6PC3 glucose 6 phosphatase, catalytic, 3 0.190165
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.190032
KLHL17 kelch-like family member 17 0.18941
CTSZ cathepsin Z 0.189296
SCAP SREBF chaperone 0.188766
DGKZ diacylglycerol kinase, zeta 0.188398
CFHR1 complement factor H-related 1 0.18832
DGKA diacylglycerol kinase, alpha 80kDa 0.188226
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.18821
SZRD1 SUZ RNA binding domain containing 1 0.187524
HOXB3 homeobox B3 0.187372
UNC13D unc-13 homolog D (C. elegans) 0.187025
VAMP8 vesicle-associated membrane protein 8 0.186848
UNC13A unc-13 homolog A (C. elegans) 0.186812
UNC13B unc-13 homolog B (C. elegans) 0.186776
CCL8 chemokine (C-C motif) ligand 8 0.186758
GLG1 golgi glycoprotein 1 0.185938
IL1RL1 interleukin 1 receptor-like 1 0.185802
LTBP3 latent transforming growth factor beta binding protein 3 0.185505
DUOXA1 dual oxidase maturation factor 1 0.185485
LAMA5 laminin, alpha 5 0.185221
CARM1 coactivator-associated arginine methyltransferase 1 0.184951
LTBP2 latent transforming growth factor beta binding protein 2 0.184824
FLOT2 flotillin 2 0.184675
SREBF2 sterol regulatory element binding transcription factor 2 0.184124
NBPF1 neuroblastoma breakpoint family, member 1 0.183689
STYK1 serine/threonine/tyrosine kinase 1 0.183618
PMP2 peripheral myelin protein 2 0.18331
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.182944
LAMC2 laminin, gamma 2 0.182466
BDH1 3-hydroxybutyrate dehydrogenase, type 1 0.182414
ICT1 immature colon carcinoma transcript 1 0.182388
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 0.182336
ICOSLG inducible T-cell co-stimulator ligand 0.182336
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.18218
DSP desmoplakin 0.182153
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.181282
ATF4 activating transcription factor 4 0.181282
DSPP dentin sialophosphoprotein 0.180997
CCNB2 cyclin B2 0.180735
PRDM2 PR domain containing 2, with ZNF domain 0.180706
PRSS8 protease, serine, 8 0.180646
ULK1 unc-51 like autophagy activating kinase 1 0.180617
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.179855
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.179569
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.179441