altered tumor pathology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any changes associated with the chemistry, immunohistology, cellular alterations or environmental interactions of tumors compared to the expected state (Mammalian Phenotype Ontology, MP_0010639)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010639
Similar Terms
Downloads & Tools

Genes

127 gene mutations causing the altered tumor pathology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACE angiotensin I converting enzyme
ADAM15 ADAM metallopeptidase domain 15
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ANTXR1 anthrax toxin receptor 1
ANXA1 annexin A1
APC adenomatous polyposis coli
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
AR androgen receptor
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ATF2 activating transcription factor 2
ATF3 activating transcription factor 3
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
BRAF B-Raf proto-oncogene, serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CCM2L cerebral cavernous malformation 2-like
CCR2 chemokine (C-C motif) receptor 2
CD226 CD226 molecule
CD248 CD248 molecule, endosialin
CD44 CD44 molecule (Indian blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CST3 cystatin C
CXCL16 chemokine (C-X-C motif) ligand 16
CXCR2 chemokine (C-X-C motif) receptor 2
CYBB cytochrome b-245, beta polypeptide
CYGB cytoglobin
DOT1L DOT1-like histone H3K79 methyltransferase
E2F1 E2F transcription factor 1
EPHA2 EPH receptor A2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FASLG Fas ligand (TNF superfamily, member 6)
FBLN5 fibulin 5
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FOS FBJ murine osteosarcoma viral oncogene homolog
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GPR68 G protein-coupled receptor 68
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
H19 H19, imprinted maternally expressed transcript (non-protein coding)
H2AFX H2A histone family, member X
HCST hematopoietic cell signal transducer
HIC1 hypermethylated in cancer 1
HMGN1 high mobility group nucleosome binding domain 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IL12RB2 interleukin 12 receptor, beta 2
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL22RA2 interleukin 22 receptor, alpha 2
IL5 interleukin 5
IL5RA interleukin 5 receptor, alpha
IL6R interleukin 6 receptor
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAM3 junctional adhesion molecule 3
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF10 Kruppel-like factor 10
KRAS Kirsten rat sarcoma viral oncogene homolog
LATS1 large tumor suppressor kinase 1
LEP leptin
LEPR leptin receptor
LYST lysosomal trafficking regulator
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MIR122 microRNA 122
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MSH2 mutS homolog 2
MSI2 musashi RNA-binding protein 2
MSMB microseminoprotein, beta-
MUC1 mucin 1, cell surface associated
NF2 neurofibromin 2 (merlin)
NRP1 neuropilin 1
PAQR3 progestin and adipoQ receptor family member III
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PGF placental growth factor
PLAU plasminogen activator, urokinase
PLCL1 phospholipase C-like 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLG plasminogen
PLK3 polo-like kinase 3
POSTN periostin, osteoblast specific factor
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRDX1 peroxiredoxin 1
PRF1 perforin 1 (pore forming protein)
PTEN phosphatase and tensin homolog
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RALGDS ral guanine nucleotide dissociation stimulator
RB1 retinoblastoma 1
RNF19B ring finger protein 19B
RRAS related RAS viral (r-ras) oncogene homolog
RRAS2 related RAS viral (r-ras) oncogene homolog 2
S1PR2 sphingosine-1-phosphate receptor 2
SELL selectin L
SF1 splicing factor 1
SKIL SKI-like proto-oncogene
SMAD3 SMAD family member 3
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STAB2 stabilin 2
STAG1 stromal antigen 1
STARD13 StAR-related lipid transfer (START) domain containing 13
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TGM2 transglutaminase 2
TICAM1 toll-like receptor adaptor molecule 1
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOM1L2 target of myb1-like 2 (chicken)
TP53 tumor protein p53
TPX2 TPX2, microtubule-associated
TRIM27 tripartite motif containing 27
TSC1 tuberous sclerosis 1