altered tumor morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of a given tumor type compared to controls (Mammalian Phenotype Ontology, MP_0003448)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003448
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Genes

92 gene mutations causing the altered tumor morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACE angiotensin I converting enzyme
ADAM15 ADAM metallopeptidase domain 15
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ANTXR1 anthrax toxin receptor 1
ANXA1 annexin A1
APC adenomatous polyposis coli
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
AR androgen receptor
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CCM2L cerebral cavernous malformation 2-like
CCR2 chemokine (C-C motif) receptor 2
CD226 CD226 molecule
CD248 CD248 molecule, endosialin
CD44 CD44 molecule (Indian blood group)
CDKN2A cyclin-dependent kinase inhibitor 2A
CXCL16 chemokine (C-X-C motif) ligand 16
CXCR2 chemokine (C-X-C motif) receptor 2
CYBB cytochrome b-245, beta polypeptide
CYGB cytoglobin
DOT1L DOT1-like histone H3K79 methyltransferase
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FBLN5 fibulin 5
FOS FBJ murine osteosarcoma viral oncogene homolog
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GPR68 G protein-coupled receptor 68
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
H19 H19, imprinted maternally expressed transcript (non-protein coding)
H2AFX H2A histone family, member X
HCST hematopoietic cell signal transducer
HPRT1 hypoxanthine phosphoribosyltransferase 1
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNB1 interferon, beta 1, fibroblast
IL12RB2 interleukin 12 receptor, beta 2
IL1B interleukin 1, beta
IL22RA2 interleukin 22 receptor, alpha 2
IL6R interleukin 6 receptor
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF10 Kruppel-like factor 10
KRAS Kirsten rat sarcoma viral oncogene homolog
LATS1 large tumor suppressor kinase 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MIR122 microRNA 122
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MSH2 mutS homolog 2
MSI2 musashi RNA-binding protein 2
MUC1 mucin 1, cell surface associated
NF2 neurofibromin 2 (merlin)
NRP1 neuropilin 1
PAQR3 progestin and adipoQ receptor family member III
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PGF placental growth factor
PLAU plasminogen activator, urokinase
PLCL1 phospholipase C-like 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLG plasminogen
PLK3 polo-like kinase 3
POSTN periostin, osteoblast specific factor
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRDX1 peroxiredoxin 1
PRF1 perforin 1 (pore forming protein)
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RALGDS ral guanine nucleotide dissociation stimulator
RNF19B ring finger protein 19B
RRAS2 related RAS viral (r-ras) oncogene homolog 2
S1PR2 sphingosine-1-phosphate receptor 2
SELL selectin L
SF1 splicing factor 1
SKIL SKI-like proto-oncogene
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STAG1 stromal antigen 1
STARD13 StAR-related lipid transfer (START) domain containing 13
TGM2 transglutaminase 2
TICAM1 toll-like receptor adaptor molecule 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TRIM27 tripartite motif containing 27
TSC1 tuberous sclerosis 1