altered metastatic potential Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description altered likelihood of a tumor cell spreading from the site of the initial tumor formation and forming a secondary tumor at another site not directly connected with it (Mammalian Phenotype Ontology, MP_0000858)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000858
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Genes

51 gene mutations causing the altered metastatic potential phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ANXA1 annexin A1
APC adenomatous polyposis coli
ATF2 activating transcription factor 2
ATF3 activating transcription factor 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
CCM2L cerebral cavernous malformation 2-like
CD226 CD226 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CST3 cystatin C
CXCR2 chemokine (C-X-C motif) receptor 2
CYBB cytochrome b-245, beta polypeptide
E2F1 E2F transcription factor 1
EPHA2 EPH receptor A2
FASLG Fas ligand (TNF superfamily, member 6)
FBLN5 fibulin 5
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FOS FBJ murine osteosarcoma viral oncogene homolog
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
HCST hematopoietic cell signal transducer
HIC1 hypermethylated in cancer 1
HMGN1 high mobility group nucleosome binding domain 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL5 interleukin 5
IL5RA interleukin 5 receptor, alpha
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
JAM3 junctional adhesion molecule 3
LEP leptin
LEPR leptin receptor
LYST lysosomal trafficking regulator
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MMP9 matrix metallopeptidase 9
MSMB microseminoprotein, beta-
PLAU plasminogen activator, urokinase
PLD1 phospholipase D1, phosphatidylcholine-specific
PTEN phosphatase and tensin homolog
RB1 retinoblastoma 1
RNF19B ring finger protein 19B
SELL selectin L
SMAD3 SMAD family member 3
STAB2 stabilin 2
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TOM1L2 target of myb1-like 2 (chicken)
TP53 tumor protein p53
TPX2 TPX2, microtubule-associated