alprenolol-3188 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the alprenolol-3188 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
AMPD3 adenosine monophosphate deaminase 3
ARSD arylsulfatase D
ASB1 ankyrin repeat and SOCS box containing 1
BTF3P11 basic transcription factor 3 pseudogene 11
CALB1 calbindin 1, 28kDa
CCL22 chemokine (C-C motif) ligand 22
CD1A CD1a molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK18 cyclin-dependent kinase 18
CEMIP cell migration inducing protein, hyaluronan binding
CEP250 centrosomal protein 250kDa
CIZ1 CDKN1A interacting zinc finger protein 1
CLCN7 chloride channel, voltage-sensitive 7
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPED1 cadherin-like and PC-esterase domain containing 1
CRYGD crystallin, gamma D
CTIF CBP80/20-dependent translation initiation factor
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DLX4 distal-less homeobox 4
DUOX2 dual oxidase 2
FAM212B family with sequence similarity 212, member B
FGF12 fibroblast growth factor 12
FH fumarate hydratase
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GGT1 gamma-glutamyltransferase 1
GJB3 gap junction protein, beta 3, 31kDa
GNRHR gonadotropin-releasing hormone receptor
GPR182 G protein-coupled receptor 182
GPSM3 G-protein signaling modulator 3
GYPB glycophorin B (MNS blood group)
GZMK granzyme K (granzyme 3; tryptase II)
HABP2 hyaluronan binding protein 2
HAMP hepcidin antimicrobial peptide
HAP1 huntingtin-associated protein 1
ING2 inhibitor of growth family, member 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
JAK2 Janus kinase 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0040 KIAA0040
LAMP1 lysosomal-associated membrane protein 1
LCAT lecithin-cholesterol acyltransferase
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LPAR1 lysophosphatidic acid receptor 1
MAP4 microtubule-associated protein 4
MCTP1 multiple C2 domains, transmembrane 1
MED31 mediator complex subunit 31
MEGF6 multiple EGF-like-domains 6
MIA3 melanoma inhibitory activity family, member 3
MIER2 mesoderm induction early response 1, family member 2
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MOGAT2 monoacylglycerol O-acyltransferase 2
MRC2 mannose receptor, C type 2
MRPL41 mitochondrial ribosomal protein L41
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYCNOS MYCN opposite strand
MYOZ1 myozenin 1
N4BP2L1 NEDD4 binding protein 2-like 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NOX3 NADPH oxidase 3
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OTOR otoraplin
PAPPA2 pappalysin 2
PCDH11Y protocadherin 11 Y-linked
PCSK6 proprotein convertase subtilisin/kexin type 6
PHF1 PHD finger protein 1
PHOX2A paired-like homeobox 2a
PIDD1 p53-induced death domain protein 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLAC4 placenta-specific 4
PLCD1 phospholipase C, delta 1
POU1F1 POU class 1 homeobox 1
PRSS16 protease, serine, 16 (thymus)
PSD4 pleckstrin and Sec7 domain containing 4
RAB6B RAB6B, member RAS oncogene family
RASAL2 RAS protein activator like 2
RPL35A ribosomal protein L35a
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
RYR2 ryanodine receptor 2 (cardiac)
SEC24A SEC24 family member A
SETD1A SET domain containing 1A
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SNTA1 syntrophin, alpha 1
SOX15 SRY (sex determining region Y)-box 15
SRSF5 serine/arginine-rich splicing factor 5
STK24 serine/threonine kinase 24
STOM stomatin
TDRKH tudor and KH domain containing
TENM1 teneurin transmembrane protein 1
THY1 Thy-1 cell surface antigen
TTC39A tetratricopeptide repeat domain 39A
ZNF668 zinc finger protein 668
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABHD17B abhydrolase domain containing 17B
ADM adrenomedullin
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AFAP1 actin filament associated protein 1
ALS2CL ALS2 C-terminal like
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD5 ATPase family, AAA domain containing 5
BAX BCL2-associated X protein
C11ORF30 chromosome 11 open reading frame 30
C17ORF80 chromosome 17 open reading frame 80
C22ORF46 chromosome 22 open reading frame 46
CAMKV CaM kinase-like vesicle-associated
CCNK cyclin K
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CIDEB cell death-inducing DFFA-like effector b
CLCN6 chloride channel, voltage-sensitive 6
CRYGC crystallin, gamma C
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCAF13 DDB1 and CUL4 associated factor 13
DSCAM Down syndrome cell adhesion molecule
EDAR ectodysplasin A receptor
EMID1 EMI domain containing 1
ENO3 enolase 3 (beta, muscle)
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EXOC6B exocyst complex component 6B
FLT4 fms-related tyrosine kinase 4
FOXN2 forkhead box N2
FRS2 fibroblast growth factor receptor substrate 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAMT guanidinoacetate N-methyltransferase
GDAP1 ganglioside induced differentiation associated protein 1
GMEB1 glucocorticoid modulatory element binding protein 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2I general transcription factor IIi
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1B histone cluster 1, H1b
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AL histone cluster 1, H2al
HOXC5 homeobox C5
HOXC8 homeobox C8
HP1BP3 heterochromatin protein 1, binding protein 3
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IDI2-AS1 IDI2 antisense RNA 1
IFT140 intraflagellar transport 140
INCENP inner centromere protein antigens 135/155kDa
IRAK4 interleukin-1 receptor-associated kinase 4
KIAA0754 KIAA0754
KLK5 kallikrein-related peptidase 5
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LDHB lactate dehydrogenase B
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LYZ lysozyme
MAP9 microtubule-associated protein 9
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MCOLN3 mucolipin 3
MDM4 MDM4, p53 regulator
MPO myeloperoxidase
MTERF4 mitochondrial transcription termination factor 4
MUC3A mucin 3A, cell surface associated
NLRX1 NLR family member X1
OVGP1 oviductal glycoprotein 1, 120kDa
PARP12 poly (ADP-ribose) polymerase family, member 12
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRR4 proline rich 4 (lacrimal)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RANGRF RAN guanine nucleotide release factor
RASAL1 RAS protein activator like 1 (GAP1 like)
RASL11B RAS-like, family 11, member B
RNF122 ring finger protein 122
RPL10L ribosomal protein L10-like
SIRT6 sirtuin 6
SOCS7 suppressor of cytokine signaling 7
SRGN serglycin
TESC tescalcin
TRAIP TRAF interacting protein
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
TWF2 twinfilin actin binding protein 2
USB1 U6 snRNA biogenesis 1
VASH1 vasohibin 1
VASH2 vasohibin 2
VEGFB vascular endothelial growth factor B
WDR91 WD repeat domain 91
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF134 zinc finger protein 134
ZNF227 zinc finger protein 227
ZNF428 zinc finger protein 428
ZNF586 zinc finger protein 586
ZNF770 zinc finger protein 770