allergic conjunctivitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A chronic conjunctivitis that is an inflammation of the conjunctiva involing red, itchy, and watery eyes a resulting from an exposure to an allergen or an irritant. (Human Disease Ontology, DOID_11204)
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Genes

104 genes co-occuring with the disease allergic conjunctivitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HRH1 histamine receptor H1 1.64891
RNASE3 ribonuclease, RNase A family, 3 1.45748
CCL11 chemokine (C-C motif) ligand 11 1.30139
PTGER3 prostaglandin E receptor 3 (subtype EP3) 1.24776
SOCS5 suppressor of cytokine signaling 5 1.16093
CMA1 chymase 1, mast cell 1.03156
CHIA chitinase, acidic 0.994017
IL4 interleukin 4 0.973801
IGHE immunoglobulin heavy constant epsilon 0.939949
GPR32 G protein-coupled receptor 32 0.929173
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.927105
ICAM1 intercellular adhesion molecule 1 0.899103
CD4 CD4 molecule 0.872053
TSLP thymic stromal lymphopoietin 0.872053
TSPO translocator protein (18kDa) 0.849945
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.815104
EPX eosinophil peroxidase 0.799513
SLPI secretory leukocyte peptidase inhibitor 0.761454
TLR3 toll-like receptor 3 0.741923
CCR3 chemokine (C-C motif) receptor 3 0.722077
ALB albumin 0.715215
CRLF2 cytokine receptor-like factor 2 0.691094
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.675112
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.644192
PTGDR2 prostaglandin D2 receptor 2 0.638676
RP2 retinitis pigmentosa 2 (X-linked recessive) 0.632777
IL33 interleukin 33 0.626103
GPR135 G protein-coupled receptor 135 0.578106
VCAM1 vascular cell adhesion molecule 1 0.576939
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 0.571107
TAC1 tachykinin, precursor 1 0.556732
PLA2G10 phospholipase A2, group X 0.553627
AFF1 AF4/FMR2 family, member 1 0.532314
SOCS3 suppressor of cytokine signaling 3 0.529994
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.529608
CISH cytokine inducible SH2-containing protein 0.520346
TGM1 transglutaminase 1 0.516494
RENBP renin binding protein 0.507273
IL13 interleukin 13 0.502292
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.501909
CXCL11 chemokine (C-X-C motif) ligand 11 0.487407
CASP5 caspase 5, apoptosis-related cysteine peptidase 0.483985
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.481705
NBPF8 neuroblastoma breakpoint family, member 8 0.478289
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.475634
TLR5 toll-like receptor 5 0.474498
CD40 CD40 molecule, TNF receptor superfamily member 5 0.47374
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.448817
CCL5 chemokine (C-C motif) ligand 5 0.447311
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.442418
POLK polymerase (DNA directed) kappa 0.440538
CCL25 chemokine (C-C motif) ligand 25 0.417644
MYD88 myeloid differentiation primary response 88 0.412031
FOXP3 forkhead box P3 0.410909
ANXA1 annexin A1 0.410535
CD1D CD1d molecule 0.397843
IL1RL1 interleukin 1 receptor-like 1 0.386308
TNF tumor necrosis factor 0.359657
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.34384
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.340173
NGF nerve growth factor (beta polypeptide) 0.335778
CCL17 chemokine (C-C motif) ligand 17 0.327375
GADD45B growth arrest and DNA-damage-inducible, beta 0.324458
DLL4 delta-like 4 (Drosophila) 0.316819
CD79A CD79a molecule, immunoglobulin-associated alpha 0.316819
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.315729
MCF2 MCF.2 cell line derived transforming sequence 0.311014
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.304503
SACS sacsin molecular chaperone 0.303781
FLG filaggrin 0.299452
CCR4 chemokine (C-C motif) receptor 4 0.294413
IL1B interleukin 1, beta 0.28831
CCR7 chemokine (C-C motif) receptor 7 0.284728
TLR2 toll-like receptor 2 0.284371
ICAM2 intercellular adhesion molecule 2 0.27687
FLNA filamin A, alpha 0.275445
CXCL10 chemokine (C-X-C motif) ligand 10 0.27153
CYSLTR2 cysteinyl leukotriene receptor 2 0.269753
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.266203
JAG2 jagged 2 0.264785
MIXL1 Mix paired-like homeobox 0.264431
PTGDR prostaglandin D2 receptor (DP) 0.256299
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.249257
WARS tryptophanyl-tRNA synthetase 0.246799
HLA-C major histocompatibility complex, class I, C 0.240497
CD70 CD70 molecule 0.239799
TBXA2R thromboxane A2 receptor 0.236312
PTAFR platelet-activating factor receptor 0.234573
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 0.234225
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.223509
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.222479
CCR2 chemokine (C-C motif) receptor 2 0.221108
BAG1 BCL2-associated athanogene 0.213959
SRCIN1 SRC kinase signaling inhibitor 1 0.212945
GAN gigaxonin 0.211934
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.210589
PRSS21 protease, serine, 21 (testisin) 0.191719
NBPF10 neuroblastoma breakpoint family, member 10 0.183248
IL5 interleukin 5 0.180937
CCL19 chemokine (C-C motif) ligand 19 0.178682
IL10 interleukin 10 0.177029
CXCL8 chemokine (C-X-C motif) ligand 8 0.173057
IL6 interleukin 6 0.163317
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.158951