alclometasone-6229 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the alclometasone-6229 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ABLIM3 actin binding LIM protein family, member 3
AK2 adenylate kinase 2
AKR1C1 aldo-keto reductase family 1, member C1
ALOX15B arachidonate 15-lipoxygenase, type B
APOC1 apolipoprotein C-I
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ATAD5 ATPase family, AAA domain containing 5
AVPR1B arginine vasopressin receptor 1B
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C4BPA complement component 4 binding protein, alpha
CDC25A cell division cycle 25A
CRIP1 cysteine-rich protein 1 (intestinal)
CST6 cystatin E/M
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DRD2 dopamine receptor D2
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
EFNA5 ephrin-A5
EML3 echinoderm microtubule associated protein like 3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPHA2 EPH receptor A2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GFER growth factor, augmenter of liver regeneration
GLRX3 glutaredoxin 3
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GUSBP3 glucuronidase, beta pseudogene 3
HFE hemochromatosis
HIST1H2AJ histone cluster 1, H2aj
HRASLS2 HRAS-like suppressor 2
IGHM immunoglobulin heavy constant mu
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ING4 inhibitor of growth family, member 4
ITGB6 integrin, beta 6
KDM6B lysine (K)-specific demethylase 6B
KLHL25 kelch-like family member 25
LAMB4 laminin, beta 4
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LIG3 ligase III, DNA, ATP-dependent
LOC390998 ribosomal protein L10 pseudogene
LONP2 lon peptidase 2, peroxisomal
LPIN2 lipin 2
LY6D lymphocyte antigen 6 complex, locus D
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MEP1B meprin A, beta
MKL1 megakaryoblastic leukemia (translocation) 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTMR2 myotubularin related protein 2
MXD4 MAX dimerization protein 4
NADK NAD kinase
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NFIB nuclear factor I/B
NMT1 N-myristoyltransferase 1
OXCT2 3-oxoacid CoA transferase 2
PAOX polyamine oxidase (exo-N4-amino)
PDE12 phosphodiesterase 12
PDZD2 PDZ domain containing 2
PHACTR4 phosphatase and actin regulator 4
PRB1 proline-rich protein BstNI subfamily 1
PTCRA pre T-cell antigen receptor alpha
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RANBP3 RAN binding protein 3
RERE arginine-glutamic acid dipeptide (RE) repeats
RHBG Rh family, B glycoprotein (gene/pseudogene)
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)
RUFY3 RUN and FYVE domain containing 3
SAFB2 scaffold attachment factor B2
SAMD9 sterile alpha motif domain containing 9
SCN10A sodium channel, voltage gated, type X alpha subunit
SEC63 SEC63 homolog (S. cerevisiae)
SERHL2 serine hydrolase-like 2
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SMIM14 small integral membrane protein 14
SMTN smoothelin
SPTAN1 spectrin, alpha, non-erythrocytic 1
SSPN sarcospan
TAOK1 TAO kinase 1
TLE2 transducin-like enhancer of split 2
TM2D1 TM2 domain containing 1
TRIM62 tripartite motif containing 62
TTLL5 tubulin tyrosine ligase-like family member 5
TUBGCP3 tubulin, gamma complex associated protein 3
ULBP1 UL16 binding protein 1
UST uronyl-2-sulfotransferase
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WSCD1 WSC domain containing 1
YY1 YY1 transcription factor
ZFAND6 zinc finger, AN1-type domain 6
ZFPL1 zinc finger protein-like 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF16 zinc finger protein 16
ZNF286A zinc finger protein 286A
ZNF324 zinc finger protein 324
ZNF862 zinc finger protein 862
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
AARSD1 alanyl-tRNA synthetase domain containing 1
ACVR2A activin A receptor, type IIA
AGBL5 ATP/GTP binding protein-like 5
AKAP12 A kinase (PRKA) anchor protein 12
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APH1B APH1B gamma secretase subunit
ATP13A2 ATPase type 13A2
BAK1 BCL2-antagonist/killer 1
BCL7B B-cell CLL/lymphoma 7B
BEX4 brain expressed, X-linked 4
CCDC130 coiled-coil domain containing 130
CCDC25 coiled-coil domain containing 25
CCNJ cyclin J
CGREF1 cell growth regulator with EF-hand domain 1
CISH cytokine inducible SH2-containing protein
COL4A5 collagen, type IV, alpha 5
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DEAF1 DEAF1 transcription factor
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNMBP dynamin binding protein
ERCC3 excision repair cross-complementation group 3
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC5 exocyst complex component 5
FAM63A family with sequence similarity 63, member A
FAM86C1 family with sequence similarity 86, member C1
FBRS fibrosin
FBXL15 F-box and leucine-rich repeat protein 15
FCHO1 FCH domain only 1
FKTN fukutin
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FZD4 frizzled class receptor 4
GDAP1 ganglioside induced differentiation associated protein 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPBP1L1 GC-rich promoter binding protein 1-like 1
GTF2B general transcription factor IIB
HIST1H1D histone cluster 1, H1d
HOOK1 hook microtubule-tethering protein 1
HOXC11 homeobox C11
INSIG2 insulin induced gene 2
INTS9 integrator complex subunit 9
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0753 KIAA0753
KIF16B kinesin family member 16B
KLHL21 kelch-like family member 21
KLHL26 kelch-like family member 26
KRBOX4 KRAB box domain containing 4
KRT8P12 keratin 8 pseudogene 12
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMNB1 lamin B1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MNX1 motor neuron and pancreas homeobox 1
MORC3 MORC family CW-type zinc finger 3
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MXD3 MAX dimerization protein 3
NPY5R neuropeptide Y receptor Y5
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PMP22 peripheral myelin protein 22
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PRPF38B pre-mRNA processing factor 38B
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTGES2 prostaglandin E synthase 2
PUS3 pseudouridylate synthase 3
RANGRF RAN guanine nucleotide release factor
RNF38 ring finger protein 38
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPL23AP7 ribosomal protein L23a pseudogene 7
SGK1 serum/glucocorticoid regulated kinase 1
SHARPIN SHANK-associated RH domain interactor
SHPK sedoheptulokinase
SKA1 spindle and kinetochore associated complex subunit 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
STAG3 stromal antigen 3
STK16 serine/threonine kinase 16
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYT17 synaptotagmin XVII
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D31 TBC1 domain family, member 31
TDRD1 tudor domain containing 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRAPPC13 trafficking protein particle complex 13
TST thiosulfate sulfurtransferase (rhodanese)
UBXN6 UBX domain protein 6
USPL1 ubiquitin specific peptidase like 1
VAV1 vav 1 guanine nucleotide exchange factor
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR44 WD repeat domain 44
ZFP36 ZFP36 ring finger protein
ZNF211 zinc finger protein 211
ZNF212 zinc finger protein 212
ZNF430 zinc finger protein 430
ZNF586 zinc finger protein 586
ZNF787 zinc finger protein 787
ZNF83 zinc finger protein 83