adult Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A maturity quality inhering in an individual by virtue of the individual having attained sexual maturity and full growth (Experimental Factor Ontology, EFO_0001272)
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Genes

929 genes co-occuring with the biological term adult in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
AAAS achalasia, adrenocortical insufficiency, alacrimia
AASDH aminoadipate-semialdehyde dehydrogenase
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACAD10 acyl-CoA dehydrogenase family, member 10
ACE angiotensin I converting enzyme
ACHE acetylcholinesterase (Yt blood group)
ACKR2 atypical chemokine receptor 2
ACKR3 atypical chemokine receptor 3
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACTA1 actin, alpha 1, skeletal muscle
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTC1 actin, alpha, cardiac muscle 1
ACTL7A actin-like 7A
ACTN3 actinin, alpha 3 (gene/pseudogene)
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
ADAM10 ADAM metallopeptidase domain 10
ADAM33 ADAM metallopeptidase domain 33
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADGRA3 adhesion G protein-coupled receptor A3
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRA2A adrenoceptor alpha 2A
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
ADRBK1 adrenergic, beta, receptor kinase 1
AGER advanced glycosylation end product-specific receptor
AGO2 argonaute RISC catalytic component 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGXT alanine-glyoxylate aminotransferase
AHR aryl hydrocarbon receptor
AHSG alpha-2-HS-glycoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALPL alkaline phosphatase, liver/bone/kidney
AMACR alpha-methylacyl-CoA racemase
AMH anti-Mullerian hormone
ANGPT1 angiopoietin 1
ANGPTL5 angiopoietin-like 5
ANKK1 ankyrin repeat and kinase domain containing 1
APOA5 apolipoprotein A-V
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
APOC3 apolipoprotein C-III
APOD apolipoprotein D
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARG1 arginase 1
ARG2 arginase 2
ARID5B AT rich interactive domain 5B (MRF1-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARX aristaless related homeobox
ASF1A anti-silencing function 1A histone chaperone
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG9A autophagy related 9A
ATG9B autophagy related 9B
ATM ATM serine/threonine kinase
ATOH1 atonal homolog 1 (Drosophila)
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATRX alpha thalassemia/mental retardation syndrome X-linked
ATXN3 ataxin 3
B2M beta-2-microglobulin
BAALC brain and acute leukemia, cytoplasmic
BACE1 beta-site APP-cleaving enzyme 1
BACE2 beta-site APP-cleaving enzyme 2
BAX BCL2-associated X protein
BBS9 Bardet-Biedl syndrome 9
BCAN brevican
BCHE butyrylcholinesterase
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L2 BCL2-like 2
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BDNF brain-derived neurotrophic factor
BIN1 bridging integrator 1
BIRC5 baculoviral IAP repeat containing 5
BIRC7 baculoviral IAP repeat containing 7
BLMH bleomycin hydrolase
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP5 bone morphogenetic protein 5
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BSG basigin (Ok blood group)
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C21ORF2 chromosome 21 open reading frame 2
C3 complement component 3
CA2 carbonic anhydrase II
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CADM1 cell adhesion molecule 1
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPN2 calpain 2, (m/II) large subunit
CARD11 caspase recruitment domain family, member 11
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CAT catalase
CAV3 caveolin 3
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL21 chemokine (C-C motif) ligand 21
CCL27 chemokine (C-C motif) ligand 27
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCNE1 cyclin E1
CCR10 chemokine (C-C motif) receptor 10
CCR2 chemokine (C-C motif) receptor 2
CCR4 chemokine (C-C motif) receptor 4
CCR9 chemokine (C-C motif) receptor 9
CD14 CD14 molecule
CD24 CD24 molecule
CD248 CD248 molecule, endosialin
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD68 CD68 molecule
CD69 CD69 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CDC20 cell division cycle 20
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH13 cadherin 13
CDH16 cadherin 16, KSP-cadherin
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDHR5 cadherin-related family member 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDX1 caudal type homeobox 1
CDX2 caudal type homeobox 2
CDX4 caudal type homeobox 4
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM20 carcinoembryonic antigen-related cell adhesion molecule 20
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CETP cholesteryl ester transfer protein, plasma
CFB complement factor B
CFH complement factor H
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHAD chondroadherin
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHIT1 chitinase 1 (chitotriosidase)
CHRM2 cholinergic receptor, muscarinic 2
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CISH cytokine inducible SH2-containing protein
CIZ1 CDKN1A interacting zinc finger protein 1
CLCA1 chloride channel accessory 1
CLN5 ceroid-lipofuscinosis, neuronal 5
CLOCK clock circadian regulator
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CNOT3 CCR4-NOT transcription complex, subunit 3
CNPY2 canopy FGF signaling regulator 2
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
COL1A1 collagen, type I, alpha 1
COL2A1 collagen, type II, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A4 collagen, type IV, alpha 4
COL4A5 collagen, type IV, alpha 5
COMT catechol-O-methyltransferase
CP ceruloplasmin (ferroxidase)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CPT2 carnitine palmitoyltransferase 2
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRBN cereblon
CREB1 cAMP responsive element binding protein 1
CREM cAMP responsive element modulator
CRH corticotropin releasing hormone
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CRLF2 cytokine receptor-like factor 2
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CSF3R colony stimulating factor 3 receptor (granulocyte)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSMD3 CUB and Sushi multiple domains 3
CSPG4 chondroitin sulfate proteoglycan 4
CST6 cystatin E/M
CTAG1B cancer/testis antigen 1B
CTF1 cardiotrophin 1
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSK cathepsin K
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYB5A cytochrome b5 type A (microsomal)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
DAP3 death associated protein 3
DAZ1 deleted in azoospermia 1
DCDC1 doublecortin domain containing 1
DCN decorin
DCX doublecortin
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DGCR8 DGCR8 microprocessor complex subunit
DGKH diacylglycerol kinase, eta
DHFR dihydrofolate reductase
DHH desert hedgehog
DICER1 dicer 1, ribonuclease type III
DIO3 deiodinase, iodothyronine, type III
DISC1 disrupted in schizophrenia 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DLX4 distal-less homeobox 4
DMBT1 deleted in malignant brain tumors 1
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13
DNM2 dynamin 2
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOT1L DOT1-like histone H3K79 methyltransferase
DPP4 dipeptidyl-peptidase 4
DPPA3 developmental pluripotency associated 3
DRD5 dopamine receptor D5
DSG2 desmoglein 2
DSG3 desmoglein 3
DTNBP1 dystrobrevin binding protein 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDN1 endothelin 1
EFNA2 ephrin-A2
EFNB2 ephrin-B2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR3 early growth response 3
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF3I eukaryotic translation initiation factor 3, subunit I
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ENG endoglin
ENO2 enolase 2 (gamma, neuronal)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPHA4 EPH receptor A4
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV6 ets variant 6
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FA2H fatty acid 2-hydroxylase
FAAH fatty acid amide hydrolase
FABP7 fatty acid binding protein 7, brain
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FASN fatty acid synthase
FBN1 fibrillin 1
FBXW12 F-box and WD repeat domain containing 12
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FEV FEV (ETS oncogene family)
FEZF2 FEZ family zinc finger 2
FGF10 fibroblast growth factor 10
FGF2 fibroblast growth factor 2 (basic)
FGF8 fibroblast growth factor 8 (androgen-induced)
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
FH fumarate hydratase
FKBP5 FK506 binding protein 5
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FMO1 flavin containing monooxygenase 1
FMO3 flavin containing monooxygenase 3
FMR1 fragile X mental retardation 1
FN1 fibronectin 1
FOSL2 FOS-like antigen 2
FOXE1 forkhead box E1
FOXL2 forkhead box L2
FOXM1 forkhead box M1
FOXP3 forkhead box P3
FSCN1 fascin actin-bundling protein 1
FTO fat mass and obesity associated
FZD5 frizzled class receptor 5
G6PC3 glucose 6 phosphatase, catalytic, 3
GAA glucosidase, alpha; acid
GAB2 GRB2-associated binding protein 2
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GADD45B growth arrest and DNA-damage-inducible, beta
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GBA glucosidase, beta, acid
GBE1 glucan (1,4-alpha-), branching enzyme 1
GCG glucagon
GCH1 GTP cyclohydrolase 1
GCK glucokinase (hexokinase 4)
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GDF2 growth differentiation factor 2
GDNF glial cell derived neurotrophic factor
GFAP glial fibrillary acidic protein
GFER growth factor, augmenter of liver regeneration
GFRA1 GDNF family receptor alpha 1
GFRA2 GDNF family receptor alpha 2
GGT1 gamma-glutamyltransferase 1
GH1 growth hormone 1
GH2 growth hormone 2
GHR growth hormone receptor
GHRH growth hormone releasing hormone
GHRHR growth hormone releasing hormone receptor
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GIPR gastric inhibitory polypeptide receptor
GJA1 gap junction protein, alpha 1, 43kDa
GJB2 gap junction protein, beta 2, 26kDa
GLA galactosidase, alpha
GLI1 GLI family zinc finger 1
GLI3 GLI family zinc finger 3
GLUL glutamate-ammonia ligase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAS GNAS complex locus
GP6 glycoprotein VI (platelet)
GPER1 G protein-coupled estrogen receptor 1
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GREM1 gremlin 1, DAN family BMP antagonist
GRHL1 grainyhead-like 1 (Drosophila)
GRHL2 grainyhead-like 2 (Drosophila)
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRM3 glutamate receptor, metabotropic 3
GRM5 glutamate receptor, metabotropic 5
GRN granulin
GRXCR1 glutaredoxin, cysteine rich 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GTDC1 glycosyltransferase-like domain containing 1
GUSB glucuronidase, beta
H3F3A H3 histone, family 3A
HAND2 heart and neural crest derivatives expressed 2
HAPLN2 hyaluronan and proteoglycan link protein 2
HAPLN4 hyaluronan and proteoglycan link protein 4
HBA1 hemoglobin, alpha 1
HBB hemoglobin, beta
HBD hemoglobin, delta
HBE1 hemoglobin, epsilon 1
HBG1 hemoglobin, gamma A
HBZ hemoglobin, zeta
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HDAC8 histone deacetylase 8
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIST1H3B histone cluster 1, H3b
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HMGA2 high mobility group AT-hook 2
HMGB2 high mobility group box 2
HNF1A HNF1 homeobox A
HNF1B HNF1 homeobox B
HNF4A hepatocyte nuclear factor 4, alpha
HOPX HOP homeobox
HOXA13 homeobox A13
HOXB4 homeobox B4
HRAS Harvey rat sarcoma viral oncogene homolog
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
HSPG2 heparan sulfate proteoglycan 2
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IBD5 inflammatory bowel disease 5
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFI16 interferon, gamma-inducible protein 16
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
IGH immunoglobulin heavy locus
IGHE immunoglobulin heavy constant epsilon
IHH indian hedgehog
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL13 interleukin 13
IL15 interleukin 15
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL23R interleukin 23 receptor
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL3 interleukin 3
IL33 interleukin 33
IL34 interleukin 34
IL36RN interleukin 36 receptor antagonist
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
IL7 interleukin 7
IL7R interleukin 7 receptor
INHA inhibin, alpha
INHBA inhibin, beta A
INHBB inhibin, beta B
INS insulin
INSIG2 insulin induced gene 2
IRF4 interferon regulatory factor 4
IRG1 immunoresponsive 1 homolog (mouse)
IRGM immunity-related GTPase family, M
IRS1 insulin receptor substrate 1
ISL2 ISL LIM homeobox 2
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
ITGA9 integrin, alpha 9
ITGAD integrin, alpha D
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB6 integrin, beta 6
IVL involucrin
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JUND jun D proto-oncogene
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNK3 potassium channel, two pore domain subfamily K, member 3
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KDR kinase insert domain receptor
KIAA0319 KIAA0319
KIAA1549 KIAA1549
KIF14 kinesin family member 14
KIF5A kinesin family member 5A
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KISS1 KiSS-1 metastasis-suppressor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KL klotho
KLF1 Kruppel-like factor 1 (erythroid)
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLK6 kallikrein-related peptidase 6
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
KRIT1 KRIT1, ankyrin repeat containing
KRT15 keratin 15, type I
KRT17 keratin 17, type I
KRT18 keratin 18, type I
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAMA1 laminin, alpha 1
LCN2 lipocalin 2
LCRB locus control region, beta
LDHA lactate dehydrogenase A
LEFTY2 left-right determination factor 2
LEP leptin
LEPR leptin receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LHCGR luteinizing hormone/choriogonadotropin receptor
LHX1 LIM homeobox 1
LHX3 LIM homeobox 3
LHX8 LIM homeobox 8
LIF leukemia inhibitory factor
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LIN28A lin-28 homolog A (C. elegans)
LIN28B lin-28 homolog B (C. elegans)
LIN7A lin-7 homolog A (C. elegans)
LIN7B lin-7 homolog B (C. elegans)
LIN7C lin-7 homolog C (C. elegans)
LINS lines homolog (Drosophila)
LMNA lamin A/C
LMNB1 lamin B1
LMO4 LIM domain only 4
LOXL1 lysyl oxidase-like 1
LPA lipoprotein, Lp(a)
LRP5 low density lipoprotein receptor-related protein 5
LRRK1 leucine-rich repeat kinase 1
LRRK2 leucine-rich repeat kinase 2
LRRTM3 leucine rich repeat transmembrane neuronal 3
LY86 lymphocyte antigen 86
LYST lysosomal trafficking regulator
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAGEA3 melanoma antigen family A3
MAGEA4 melanoma antigen family A4
MAGED1 melanoma antigen family D1
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPT microtubule-associated protein tau
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MBL2 mannose-binding lectin (protein C) 2, soluble
MC4R melanocortin 4 receptor
MDH1 malate dehydrogenase 1, NAD (soluble)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MEIS1 Meis homeobox 1
MERTK MER proto-oncogene, tyrosine kinase
MEST mesoderm specific transcript
MET MET proto-oncogene, receptor tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MGMT O-6-methylguanine-DNA methyltransferase
MID1 midline 1
MIDN midnolin
MIR105-1 microRNA 105-1
MIR105-2 microRNA 105-2
MIR106B microRNA 106b
MIR1225 microRNA 1225
MIR133B microRNA 133b
MIR145 microRNA 145
MIR15A microRNA 15a
MIR16-1 microRNA 16-1
MIR181A1 microRNA 181a-1
MIR181B1 microRNA 181b-1
MIR181B2 microRNA 181b-2
MIR184 microRNA 184
MIR1915 microRNA 1915
MIR208A microRNA 208a
MIR20A microRNA 20a
MIR21 microRNA 21
MIR223 microRNA 223
MIR7-1 microRNA 7-1
MIR7-2 microRNA 7-2
MIR7-3 microRNA 7-3
MIRLET7A1 microRNA let-7a-1
MKI67 marker of proliferation Ki-67
MKL1 megakaryoblastic leukemia (translocation) 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MN1 meningioma (disrupted in balanced translocation) 1
MNDA myeloid cell nuclear differentiation antigen
MORC3 MORC family CW-type zinc finger 3
MPO myeloperoxidase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH2 mutS homolog 2
MSI2 musashi RNA-binding protein 2
MSTN myostatin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUSK muscle, skeletal, receptor tyrosine kinase
MVP major vault protein
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBPC1 myosin binding protein C, slow type
MYBPC3 myosin binding protein C, cardiac
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYLIP myosin regulatory light chain interacting protein
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NCAM1 neural cell adhesion molecule 1
NCS1 neuronal calcium sensor 1
NDRG2 NDRG family member 2
NEO1 neogenin 1
NES nestin
NEUROG3 neurogenin 3
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGFR nerve growth factor receptor
NKX2-1 NK2 homeobox 1
NKX2-5 NK2 homeobox 5
NNAT neuronatin
NOBOX NOBOX oogenesis homeobox
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOG noggin
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOVA2 neuro-oncological ventral antigen 2
NOX4 NADPH oxidase 4
NPC1 Niemann-Pick disease, type C1
NPC2 Niemann-Pick disease, type C2
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPPC natriuretic peptide C
NPR1 natriuretic peptide receptor 1
NPR2 natriuretic peptide receptor 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR2E1 nuclear receptor subfamily 2, group E, member 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRG1 neuregulin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUP214 nucleoporin 214kDa
NUP98 nucleoporin 98kDa
OLIG2 oligodendrocyte lineage transcription factor 2
OPRM1 opioid receptor, mu 1
ORAI1 ORAI calcium release-activated calcium modulator 1
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
PALLD palladin, cytoskeletal associated protein
PANK2 pantothenate kinase 2
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAX2 paired box 2
PAX5 paired box 5
PAX8 paired box 8
PBK PDZ binding kinase
PCDH11X protocadherin 11 X-linked
PCDH11Y protocadherin 11 Y-linked
PCSK1 proprotein convertase subtilisin/kexin type 1
PCSK9 proprotein convertase subtilisin/kexin type 9
PDCD1 programmed cell death 1
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDGFC platelet derived growth factor C
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDLIM7 PDZ and LIM domain 7 (enigma)
PDX1 pancreatic and duodenal homeobox 1
PDYN prodynorphin
PEX10 peroxisomal biogenesis factor 10
PF4 platelet factor 4
PGR progesterone receptor
PHACTR3 phosphatase and actin regulator 3
PHB prohibitin
PIAS3 protein inhibitor of activated STAT, 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PINK1 PTEN induced putative kinase 1
PITX2 paired-like homeodomain 2
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLAU plasminogen activator, urokinase
POLG polymerase (DNA directed), gamma
PON1 paraoxonase 1
POU2F1 POU class 2 homeobox 1
POU5F1 POU class 5 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PPID peptidylprolyl isomerase D
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPT1 palmitoyl-protein thioesterase 1
PRAME preferentially expressed antigen in melanoma
PRDM16 PR domain containing 16
PRDM2 PR domain containing 2, with ZNF domain
PRF1 perforin 1 (pore forming protein)
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROK1 prokineticin 1
PROM1 prominin 1
PROM2 prominin 2
PROX1 prospero homeobox 1
PRPH2 peripherin 2 (retinal degeneration, slow)
PSEN1 presenilin 1
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTHLH parathyroid hormone-like hormone
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
QPCT glutaminyl-peptide cyclotransferase
QSOX2 quiescin Q6 sulfhydryl oxidase 2
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RARB retinoic acid receptor, beta
RB1 retinoblastoma 1
RBP4 retinol binding protein 4, plasma
RBPMS2 RNA binding protein with multiple splicing 2
RELN reelin
REST RE1-silencing transcription factor
RET ret proto-oncogene
RETN resistin
RFPL4A ret finger protein-like 4A
RFT1 RFT1 homolog (S. cerevisiae)
RGR retinal G protein coupled receptor
ROR1 receptor tyrosine kinase-like orphan receptor 1
RTN4 reticulon 4
RTN4R reticulon 4 receptor
RTN4RL1 reticulon 4 receptor-like 1
RTN4RL2 reticulon 4 receptor-like 2
RUNX1 runt-related transcription factor 1
RYK receptor-like tyrosine kinase
RYR1 ryanodine receptor 1 (skeletal)
RYR3 ryanodine receptor 3
S100B S100 calcium binding protein B
SAMHD1 SAM domain and HD domain 1
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN2A sodium channel, voltage gated, type II alpha subunit
SCN3A sodium channel, voltage gated, type III alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SEPP1 selenoprotein P, plasma, 1
SEPT9 septin 9
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SET SET nuclear proto-oncogene
SETD2 SET domain containing 2
SETX senataxin
SFRP1 secreted frizzled-related protein 1
SFTPA1 surfactant protein A1
SFTPA2 surfactant protein A2
SFTPD surfactant protein D
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
SHBG sex hormone-binding globulin
SHH sonic hedgehog
SIRT1 sirtuin 1
SIX1 SIX homeobox 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC22A25 solute carrier family 22, member 25
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC26A5 solute carrier family 26 (anion exchanger), member 5
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMAD1 SMAD family member 1
SMAD7 SMAD family member 7
SMN2 survival of motor neuron 2, centromeric
SMO smoothened, frizzled class receptor
SNAP25 synaptosomal-associated protein, 25kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNRPN small nuclear ribonucleoprotein polypeptide N
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOSTDC1 sclerostin domain containing 1
SOX1 SRY (sex determining region Y)-box 1
SOX10 SRY (sex determining region Y)-box 10
SOX2 SRY (sex determining region Y)-box 2
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
SP1 Sp1 transcription factor
SP110 SP110 nuclear body protein
SPAST spastin
SPI1 Spi-1 proto-oncogene
SPINK1 serine peptidase inhibitor, Kazal type 1
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPZ1 spermatogenic leucine zipper 1
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SSBP1 single-stranded DNA binding protein 1, mitochondrial
ST5 suppression of tumorigenicity 5
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK3 serine/threonine kinase 3
STMN1 stathmin 1
STXBP2 syntaxin binding protein 2
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
SULF2 sulfatase 2
SYCP3 synaptonemal complex protein 3
SYP synaptophysin
TAL1 T-cell acute lymphocytic leukemia 1
TAS2R38 taste receptor, type 2, member 38
TBX4 T-box 4
TBX5 T-box 5
TCF4 transcription factor 4
TCN2 transcobalamin II
TCOF1 Treacher Collins-Franceschetti syndrome 1
TEK TEK tyrosine kinase, endothelial
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TET2 tet methylcytosine dioxygenase 2
TFE3 transcription factor binding to IGHM enhancer 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TH tyrosine hydroxylase
THBS2 thrombospondin 2
THBS3 thrombospondin 3
THPO thrombopoietin
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
THSD1 thrombospondin, type I, domain containing 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLL1 tolloid-like 1
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR8 toll-like receptor 8
TLX1 T-cell leukemia homeobox 1
TLX3 T-cell leukemia homeobox 3
TMEM18 transmembrane protein 18
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNNI2 troponin I type 2 (skeletal, fast)
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TOP3A topoisomerase (DNA) III alpha
TOR1A torsin family 1, member A (torsin A)
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TPM1 tropomyosin 1 (alpha)
TPO thyroid peroxidase
TRD T cell receptor delta locus
TRH thyrotropin-releasing hormone
TRIM33 tripartite motif containing 33
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TSHR thyroid stimulating hormone receptor
TSPO translocator protein (18kDa)
TXN thioredoxin
TXNIP thioredoxin interacting protein
UBA1 ubiquitin-like modifier activating enzyme 1
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
UNC13D unc-13 homolog D (C. elegans)
UTF1 undifferentiated embryonic cell transcription factor 1
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VASP vasodilator-stimulated phosphoprotein
VCAN versican
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
VLDLR very low density lipoprotein receptor
VSX2 visual system homeobox 2
VWF von Willebrand factor
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
WLS wntless Wnt ligand secretion mediator
WNT1 wingless-type MMTV integration site family, member 1
WNT5A wingless-type MMTV integration site family, member 5A
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
YAP1 Yes-associated protein 1
YBX1 Y box binding protein 1
ZBTB38 zinc finger and BTB domain containing 38
ZEB1 zinc finger E-box binding homeobox 1
ZEB2 zinc finger E-box binding homeobox 2
ZFP42 ZFP42 zinc finger protein
ZNF382 zinc finger protein 382
ZNF469 zinc finger protein 469