adrenal gland cancer Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An endocrine gland cancer located_in the adrenal glands which are located above the kidneys. (Human Disease Ontology, DOID_3953)
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Genes

259 genes co-occuring with the disease adrenal gland cancer in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
POMC proopiomelanocortin 1.98296
NR5A1 nuclear receptor subfamily 5, group A, member 1 1.73869
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1.6669
TP53 tumor protein p53 1.49833
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 1.36814
IGF2 insulin-like growth factor 2 1.36379
MRPL48 mitochondrial ribosomal protein L48 1.32803
REN renin 1.24993
STAR steroidogenic acute regulatory protein 1.24602
MLANA melan-A 1.2018
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 1.16992
FATE1 fetal and adult testis expressed 1 1.16906
TM7SF2 transmembrane 7 superfamily member 2 1.149
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 1.10343
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.07278
MEN1 multiple endocrine neoplasia I 1.07236
SYP synaptophysin 1.04209
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.02692
ZNF367 zinc finger protein 367 1.0206
CRH corticotropin releasing hormone 1.01554
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 0.979268
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.957868
INHA inhibin, alpha 0.951187
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 0.924626
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 0.922149
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.902389
TSSC1 tumor suppressing subtransferable candidate 1 0.899924
FDX1 ferredoxin 1 0.899103
IGF1R insulin-like growth factor 1 receptor 0.891718
PDE11A phosphodiesterase 11A 0.882701
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) 0.870825
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.816745
ENO2 enolase 2 (gamma, neuronal) 0.795002
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.783936
NPR1 natriuretic peptide receptor 1 0.771661
GUCY2C guanylate cyclase 2C 0.770844
ASCL2 achaete-scute family bHLH transcription factor 2 0.690694
CHGA chromogranin A 0.672722
NPBWR1 neuropeptides B/W receptor 1 0.67113
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 0.652484
GATA4 GATA binding protein 4 0.649323
HK3 hexokinase 3 (white cell) 0.638676
IL13RA2 interleukin 13 receptor, alpha 2 0.630813
NAP1L4 nucleosome assembly protein 1-like 4 0.607714
GHRHR growth hormone releasing hormone receptor 0.59952
CALB2 calbindin 2 0.571107
MIR210 microRNA 210 0.56722
IGF1 insulin-like growth factor 1 (somatomedin C) 0.566831
SLC16A9 solute carrier family 16, member 9 0.55712
ATG4C autophagy related 4C, cysteine peptidase 0.546644
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.526518
S100A3 S100 calcium binding protein A3 0.52536
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 0.512648
GIP gastric inhibitory polypeptide 0.511496
GNAS GNAS complex locus 0.504207
DHCR24 24-dehydrocholesterol reductase 0.497703
KCTD11 potassium channel tetramerization domain containing 11 0.495411
HOXC4 homeobox C4 0.492359
NPW neuropeptide W 0.491597
LHCGR luteinizing hormone/choriogonadotropin receptor 0.488169
TFE3 transcription factor binding to IGHM enhancer 3 0.478289
ARF4 ADP-ribosylation factor 4 0.47753
CHGB chromogranin B 0.472982
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.467306
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.463527
SGK3 serum/glucocorticoid regulated kinase family, member 3 0.451454
CREB1 cAMP responsive element binding protein 1 0.451078
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 0.450701
CCDC130 coiled-coil domain containing 130 0.442042
MAP2K6 mitogen-activated protein kinase kinase 6 0.43941
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.435275
AIP aryl hydrocarbon receptor interacting protein 0.434524
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 0.427015
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.418019
SLC7A4 solute carrier family 7, member 4 0.410535
INS insulin 0.406051
DDB1 damage-specific DNA binding protein 1, 127kDa 0.398962
PHOX2B paired-like homeobox 2b 0.395608
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.390397
GATA6 GATA binding protein 6 0.388538
VNN1 vanin 1 0.388166
HDAC10 histone deacetylase 10 0.385936
CD99 CD99 molecule 0.384079
HMGA1 high mobility group AT-hook 1 0.372958
CSNK2B casein kinase 2, beta polypeptide 0.367779
F10 coagulation factor X 0.357077
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.355235
ERCC1 excision repair cross-complementation group 1 0.352291
FGF4 fibroblast growth factor 4 0.344574
RBSN rabenosyn, RAB effector 0.344207
TARBP2 TAR (HIV-1) RNA binding protein 2 0.340539
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.335412
SCGB3A1 secretoglobin, family 3A, member 1 0.328105
AXIN2 axin 2 0.326646
CYB5A cytochrome b5 type A (microsomal) 0.326281
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.325552
GHSR growth hormone secretagogue receptor 0.321545
PDE8B phosphodiesterase 8B 0.320454
TCF21 transcription factor 21 0.319363
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.318272
UCN3 urocortin 3 0.315729
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 0.315729
DLEC1 deleted in lung and esophageal cancer 1 0.311377
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.311014
TKTL1 transketolase-like 1 0.309204
VIM vimentin 0.305948
NAGS N-acetylglutamate synthase 0.305948
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.305587
NOTO notochord homeobox 0.305226
MMP25 matrix metallopeptidase 25 0.303059
ICK intestinal cell (MAK-like) kinase 0.296931
BMP5 bone morphogenetic protein 5 0.295492
SGK1 serum/glucocorticoid regulated kinase 1 0.295492
MIRLET7D microRNA let-7d 0.293334
GRN granulin 0.291898
LRP1B low density lipoprotein receptor-related protein 1B 0.291539
NPPA natriuretic peptide A 0.290103
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.287593
PCNA proliferating cell nuclear antigen 0.287235
KIF1A kinesin family member 1A 0.285802
NPB neuropeptide B 0.283297
ALOX15B arachidonate 15-lipoxygenase, type B 0.280796
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.27687
UTS2 urotensin 2 0.276514
POR P450 (cytochrome) oxidoreductase 0.266558
PTER phosphotriesterase related 0.261952
KDM5C lysine (K)-specific demethylase 5C 0.261599
SPRY2 sprouty homolog 2 (Drosophila) 0.261245
PTPRF protein tyrosine phosphatase, receptor type, F 0.258064
CCNB1 cyclin B1 0.257005
AFP alpha-fetoprotein 0.256652
FSHB follicle stimulating hormone, beta polypeptide 0.249257
TBX2 T-box 2 0.246448
SHBG sex hormone-binding globulin 0.23945
STIL SCL/TAL1 interrupting locus 0.238752
FGF1 fibroblast growth factor 1 (acidic) 0.236312
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 0.232836
POU3F4 POU class 3 homeobox 4 0.232142
CCNB2 cyclin B2 0.230755
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.230063
RET ret proto-oncogene 0.227988
PLAGL1 pleiomorphic adenoma gene-like 1 0.22145
ADM adrenomedullin 0.221108
SST somatostatin 0.219057
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.218034
CETP cholesteryl ester transfer protein, plasma 0.216332
PYCARD PYD and CARD domain containing 0.214975
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.213621
PRDX5 peroxiredoxin 5 0.209918
LIG3 ligase III, DNA, ATP-dependent 0.206248
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.204263
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 0.201962
ATF1 activating transcription factor 1 0.201308
RRM1 ribonucleotide reductase M1 0.200982
TSPAN8 tetraspanin 8 0.199033
RNF31 ring finger protein 31 0.198386
DAXX death-domain associated protein 0.19742
HINT1 histidine triad nucleotide binding protein 1 0.196459
ARF1 ADP-ribosylation factor 1 0.19582
CREM cAMP responsive element modulator 0.194232
GIPR gastric inhibitory polypeptide receptor 0.192344
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.188632
EPHA7 EPH receptor A7 0.184424
APAF1 apoptotic peptidase activating factor 1 0.17896
ACADVL acyl-CoA dehydrogenase, very long chain 0.177029
SUFU suppressor of fused homolog (Drosophila) 0.171036
IGFBP3 insulin-like growth factor binding protein 3 0.170299
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 0.168148
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.168148
NOV nephroblastoma overexpressed 0.168148
C2 complement component 2 0.167682
IL1R2 interleukin 1 receptor, type II 0.166995
SMAD2 SMAD family member 2 0.166095
LXN latexin 0.163729
ALOX15 arachidonate 15-lipoxygenase 0.163317
CALCA calcitonin-related polypeptide alpha 0.161912
HRH3 histamine receptor H3 0.161523
LIFR leukemia inhibitory factor receptor alpha 0.160761
CCNE2 cyclin E2 0.160387
JAG1 jagged 1 0.160203
MSH2 mutS homolog 2 0.160203
MIR100 microRNA 100 0.160021
PTCH1 patched 1 0.160021
AVP arginine vasopressin 0.15948
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.158434
BAD BCL2-associated agonist of cell death 0.145372
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.145316
PTS 6-pyruvoyltetrahydropterin synthase 0.142018
C1QBP complement component 1, q subcomponent binding protein 0.14172
STC1 stanniocalcin 1 0.140082
QDPR quinoid dihydropteridine reductase 0.139622
PNMT phenylethanolamine N-methyltransferase 0.138133
ISL1 ISL LIM homeobox 1 0.137923
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.1377
CD177 CD177 molecule 0.137045
SP1 Sp1 transcription factor 0.137018
TYRO3 TYRO3 protein tyrosine kinase 0.13693
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.135193
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 0.134239
MT3 metallothionein 3 0.134037
PMEL premelanosome protein 0.13387
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.13383
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.133801
VDAC1 voltage-dependent anion channel 1 0.1337
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.133485
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.133475
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.133423
FGF9 fibroblast growth factor 9 0.133041
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.133041
KITLG KIT ligand 0.133008
ADRA2A adrenoceptor alpha 2A 0.132755
VIPR1 vasoactive intestinal peptide receptor 1 0.132507
NCOA1 nuclear receptor coactivator 1 0.132344
ARF3 ADP-ribosylation factor 3 0.129856
WNT2 wingless-type MMTV integration site family member 2 0.127931
PROK2 prokineticin 2 0.127827
UBAP1 ubiquitin associated protein 1 0.127315
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.127189
AKR1C3 aldo-keto reductase family 1, member C3 0.127134
RCC1 regulator of chromosome condensation 1 0.12682
CFLAR CASP8 and FADD-like apoptosis regulator 0.126149
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.126149
BIRC5 baculoviral IAP repeat containing 5 0.125692
B3GAT1 beta-1,3-glucuronyltransferase 1 0.123386
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 0.122477
PENK proenkephalin 0.121877
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.121697
PTN pleiotrophin 0.121414
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.120912
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.120885
NUMBL numb homolog (Drosophila)-like 0.120779
BCL10 B-cell CLL/lymphoma 10 0.120425
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.120096
PTEN phosphatase and tensin homolog 0.120068
CTSA cathepsin A 0.120068
LPO lactoperoxidase 0.119985
AMD1 adenosylmethionine decarboxylase 1 0.118084
MET MET proto-oncogene, receptor tyrosine kinase 0.115345
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.113552
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.113479
CREBBP CREB binding protein 0.109735
ANG angiogenin, ribonuclease, RNase A family, 5 0.109161
NCAM1 neural cell adhesion molecule 1 0.108741
GHR growth hormone receptor 0.108192
NF1 neurofibromin 1 0.105958
BBC3 BCL2 binding component 3 0.105868
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.105731
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.10541
HRH4 histamine receptor H4 0.104817
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.104207
ASPN asporin 0.103832
CXCL14 chemokine (C-X-C motif) ligand 14 0.103692
DSC3 desmocollin 3 0.103549
HCK HCK proto-oncogene, Src family tyrosine kinase 0.10326
CD63 CD63 molecule 0.103116
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.10254
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.102492
FGR FGR proto-oncogene, Src family tyrosine kinase 0.102443
PAX8 paired box 8 0.10195