adenosine phosphate-5359 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the adenosine phosphate-5359 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ALOX5 arachidonate 5-lipoxygenase
ALPPL2 alkaline phosphatase, placental-like 2
ALS2CL ALS2 C-terminal like
ANGEL2 angel homolog 2 (Drosophila)
ARC activity-regulated cytoskeleton-associated protein
ARTN artemin
ATG3 autophagy related 3
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATXN2L ataxin 2-like
CA12 carbonic anhydrase XII
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCDC85C coiled-coil domain containing 85C
CDC14A cell division cycle 14A
CDC14B cell division cycle 14B
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CENPO centromere protein O
CEP164 centrosomal protein 164kDa
COL8A1 collagen, type VIII, alpha 1
CRYGC crystallin, gamma C
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CTSF cathepsin F
CXORF21 chromosome X open reading frame 21
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DOK4 docking protein 4
EGR3 early growth response 3
EPN2 epsin 2
ERP44 endoplasmic reticulum protein 44
EVI5 ecotropic viral integration site 5
EXD3 exonuclease 3'-5' domain containing 3
EXOSC1 exosome component 1
FAM155A family with sequence similarity 155, member A
FGFR1 fibroblast growth factor receptor 1
FRMD4B FERM domain containing 4B
GSDMB gasdermin B
HR hair growth associated
HRH3 histamine receptor H3
HYAL3 hyaluronoglucosaminidase 3
IL27RA interleukin 27 receptor, alpha
IPO5 importin 5
ITGB5 integrin, beta 5
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNK10 potassium channel, two pore domain subfamily K, member 10
KLF3 Kruppel-like factor 3 (basic)
KRT15 keratin 15, type I
KRT17 keratin 17, type I
LAMP1 lysosomal-associated membrane protein 1
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC20 leucine rich repeat containing 20
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP2K6 mitogen-activated protein kinase kinase 6
MAP4 microtubule-associated protein 4
MARK4 MAP/microtubule affinity-regulating kinase 4
METTL7A methyltransferase like 7A
MINK1 misshapen-like kinase 1
MTA1 metastasis associated 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAG18 NAG18 mRNA
NCF4 neutrophil cytosolic factor 4, 40kDa
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
OMG oligodendrocyte myelin glycoprotein
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PILRA paired immunoglobin-like type 2 receptor alpha
PRB1 proline-rich protein BstNI subfamily 1
PRB3 proline-rich protein BstNI subfamily 3
PRELP proline/arginine-rich end leucine-rich repeat protein
PRKCI protein kinase C, iota
PROL1 proline rich, lacrimal 1
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTRF polymerase I and transcript release factor
RECQL5 RecQ protein-like 5
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF126P1 ring finger protein 126 pseudogene 1
RPLP2 ribosomal protein, large, P2
S100A7 S100 calcium binding protein A7
SBF1 SET binding factor 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SIX3 SIX homeobox 3
SLC12A8 solute carrier family 12, member 8
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SOCS1 suppressor of cytokine signaling 1
SPINK5 serine peptidase inhibitor, Kazal type 5
STAG3 stromal antigen 3
TACR1 tachykinin receptor 1
TAOK1 TAO kinase 1
TCF3 transcription factor 3
TEF thyrotrophic embryonic factor
TRIP11 thyroid hormone receptor interactor 11
TTLL3 tubulin tyrosine ligase-like family member 3
UNC93B1 unc-93 homolog B1 (C. elegans)
USP20 ubiquitin specific peptidase 20
VWA5A von Willebrand factor A domain containing 5A
ZBTB22 zinc finger and BTB domain containing 22
ZNF350 zinc finger protein 350

decreased expression

Symbol Name
ACAD8 acyl-CoA dehydrogenase family, member 8
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANKRD40 ankyrin repeat domain 40
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ARHGAP12 Rho GTPase activating protein 12
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ATG4A autophagy related 4A, cysteine peptidase
BCORL1 BCL6 corepressor-like 1
C1ORF115 chromosome 1 open reading frame 115
C7ORF43 chromosome 7 open reading frame 43
CDC37L1 cell division cycle 37-like 1
CEP70 centrosomal protein 70kDa
CLDN4 claudin 4
CLK4 CDC-like kinase 4
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COCH cochlin
CRBN cereblon
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYB5R1 cytochrome b5 reductase 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
EFNA1 ephrin-A1
EIF5A2 eukaryotic translation initiation factor 5A2
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
FAM118A family with sequence similarity 118, member A
FBXL15 F-box and leucine-rich repeat protein 15
FCHSD2 FCH and double SH3 domains 2
GCHFR GTP cyclohydrolase I feedback regulator
GHR growth hormone receptor
GNL1 guanine nucleotide binding protein-like 1
GPR137B G protein-coupled receptor 137B
GTF2I general transcription factor IIi
HIST1H2AC histone cluster 1, H2ac
HIST1H3H histone cluster 1, H3h
HMGB3 high mobility group box 3
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
JRKL JRK-like
MAP9 microtubule-associated protein 9
MCRS1 microspherule protein 1
METTL4 methyltransferase like 4
MGST3 microsomal glutathione S-transferase 3
MKNK2 MAP kinase interacting serine/threonine kinase 2
MMP9 matrix metallopeptidase 9
MPHOSPH6 M-phase phosphoprotein 6
MPHOSPH8 M-phase phosphoprotein 8
NDE1 nudE neurodevelopment protein 1
NUP93 nucleoporin 93kDa
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PEX13 peroxisomal biogenesis factor 13
PLAC8 placenta-specific 8
PLEKHO1 pleckstrin homology domain containing, family O member 1
PMM1 phosphomannomutase 1
PNRC1 proline-rich nuclear receptor coactivator 1
POGLUT1 protein O-glucosyltransferase 1
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPAP2C phosphatidic acid phosphatase type 2C
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PROCR protein C receptor, endothelial
PRSS8 protease, serine, 8
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
QTRT1 queuine tRNA-ribosyltransferase 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RIT1 Ras-like without CAAX 1
RLN2 relaxin 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RP2 retinitis pigmentosa 2 (X-linked recessive)
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC35A5 solute carrier family 35, member A5
SLC38A10 solute carrier family 38, member 10
SMAD5 SMAD family member 5
SNHG20 small nucleolar RNA host gene 20
SNX16 sorting nexin 16
SPHK1 sphingosine kinase 1
SPIDR scaffolding protein involved in DNA repair
SSBP2 single-stranded DNA binding protein 2
STBD1 starch binding domain 1
SYNGR3 synaptogyrin 3
SYTL2 synaptotagmin-like 2
TMEM2 transmembrane protein 2
TMEM38B transmembrane protein 38B
TMSB15A thymosin beta 15a
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TUBA3D tubulin, alpha 3d
VAV3 vav 3 guanine nucleotide exchange factor
VCPKMT valosin containing protein lysine (K) methyltransferase
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR47 WD repeat domain 47
YPEL5 yippee-like 5 (Drosophila)
ZMYM1 zinc finger, MYM-type 1
ZNF211 zinc finger protein 211
ZNF226 zinc finger protein 226