adenosine phosphate-1622 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the adenosine phosphate-1622 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
AHR aryl hydrocarbon receptor
ALAD aminolevulinate dehydratase
ARRB2 arrestin, beta 2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BCL2A1 BCL2-related protein A1
BCL6 B-cell CLL/lymphoma 6
BST1 bone marrow stromal cell antigen 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CCNE2 cyclin E2
CD300A CD300a molecule
CD86 CD86 molecule
CDC25C cell division cycle 25C
CDCA3 cell division cycle associated 3
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CHEK1 checkpoint kinase 1
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CPD carboxypeptidase D
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYB561 cytochrome b561
EGR1 early growth response 1
EGR3 early growth response 3
ELF4 E74-like factor 4 (ets domain transcription factor)
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EXOC5 exocyst complex component 5
FAM13A family with sequence similarity 13, member A
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FOS FBJ murine osteosarcoma viral oncogene homolog
FTH1 ferritin, heavy polypeptide 1
GBAP1 glucosidase, beta, acid pseudogene 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPR21 G protein-coupled receptor 21
H2BFS H2B histone family, member S (pseudogene)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX2 heme oxygenase 2
HSDL2 hydroxysteroid dehydrogenase like 2
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
INSIG2 insulin induced gene 2
JUN jun proto-oncogene
KIFC1 kinesin family member C1
KLF10 Kruppel-like factor 10
LPAR1 lysophosphatidic acid receptor 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAPK3 mitogen-activated protein kinase 3
MCL1 myeloid cell leukemia 1
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
NDRG2 NDRG family member 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NINJ1 ninjurin 1
NPM3 nucleophosmin/nucleoplasmin 3
NRP1 neuropilin 1
NT5E 5'-nucleotidase, ecto (CD73)
PADI1 peptidyl arginine deiminase, type I
PASK PAS domain containing serine/threonine kinase
PDS5A PDS5 cohesin associated factor A
PECAM1 platelet/endothelial cell adhesion molecule 1
PELI1 pellino E3 ubiquitin protein ligase 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PICALM phosphatidylinositol binding clathrin assembly protein
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PLIN2 perilipin 2
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RALB v-ral simian leukemia viral oncogene homolog B
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RBMS1 RNA binding motif, single stranded interacting protein 1
RECQL4 RecQ protein-like 4
RGS1 regulator of G-protein signaling 1
RGS13 regulator of G-protein signaling 13
RGS2 regulator of G-protein signaling 2
RNF144A ring finger protein 144A
RPL31 ribosomal protein L31
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SGK1 serum/glucocorticoid regulated kinase 1
SIKE1 suppressor of IKBKE 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC35E3 solute carrier family 35, member E3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNAP23 synaptosomal-associated protein, 23kDa
SPN sialophorin
SPPL2B signal peptide peptidase like 2B
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TBCC tubulin folding cofactor C
TMEM45A transmembrane protein 45A
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TREM1 triggering receptor expressed on myeloid cells 1
TUBA4B tubulin, alpha 4b
TUBB3 tubulin, beta 3 class III
TUBGCP2 tubulin, gamma complex associated protein 2
TXNIP thioredoxin interacting protein
ZCCHC24 zinc finger, CCHC domain containing 24

decreased expression

Symbol Name
ACOT8 acyl-CoA thioesterase 8
ACY1 aminoacylase 1
ADGRA3 adhesion G protein-coupled receptor A3
ARHGAP10 Rho GTPase activating protein 10
C10ORF2 chromosome 10 open reading frame 2
C19ORF24 chromosome 19 open reading frame 24
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CCDC130 coiled-coil domain containing 130
CCDC86 coiled-coil domain containing 86
CD82 CD82 molecule
CER1 cerberus 1, DAN family BMP antagonist
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLUH clustered mitochondria (cluA/CLU1) homolog
COASY CoA synthase
CXORF21 chromosome X open reading frame 21
DCP1A decapping mRNA 1A
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
DOLK dolichol kinase
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELP4 elongator acetyltransferase complex subunit 4
ERCC2 excision repair cross-complementation group 2
FAM208B family with sequence similarity 208, member B
FTO fat mass and obesity associated
GYPC glycophorin C (Gerbich blood group)
H1FX H1 histone family, member X
HDAC9 histone deacetylase 9
HEATR3 HEAT repeat containing 3
HSPB1 heat shock 27kDa protein 1
IFITM3 interferon induced transmembrane protein 3
IFRD2 interferon-related developmental regulator 2
IRF8 interferon regulatory factor 8
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KDM5C lysine (K)-specific demethylase 5C
KIAA0020 KIAA0020
KIAA0930 KIAA0930
KIAA1598
LAMP5 lysosomal-associated membrane protein family, member 5
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
MAGOHB mago-nashi homolog B (Drosophila)
MAPK12 mitogen-activated protein kinase 12
MDN1 MDN1, midasin homolog (yeast)
METTL1 methyltransferase like 1
MFSD10 major facilitator superfamily domain containing 10
MFSD12 major facilitator superfamily domain containing 12
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MSN moesin
MTG1 mitochondrial ribosome-associated GTPase 1
MUTYH mutY homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBAS neuroblastoma amplified sequence
NUP93 nucleoporin 93kDa
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PES1 pescadillo ribosomal biogenesis factor 1
PFAS phosphoribosylformylglycinamidine synthase
PIKFYVE phosphoinositide kinase, FYVE finger containing
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PNO1 partner of NOB1 homolog (S. cerevisiae)
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PUS1 pseudouridylate synthase 1
PUS7 pseudouridylate synthase 7 (putative)
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB5B RAB5B, member RAS oncogene family
RBM15B RNA binding motif protein 15B
RBM28 RNA binding motif protein 28
RCL1 RNA terminal phosphate cyclase-like 1
RNF44 ring finger protein 44
SFMBT1 Scm-like with four mbt domains 1
SHPK sedoheptulokinase
SIRT6 sirtuin 6
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SPX spexin hormone
STEAP3 STEAP family member 3, metalloreductase
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBL3 transducin (beta)-like 3
TCTN2 tectonic family member 2
TERT telomerase reverse transcriptase
TEX264 testis expressed 264
TFB2M transcription factor B2, mitochondrial
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSEN2 TSEN2 tRNA splicing endonuclease subunit
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBIAD1 UbiA prenyltransferase domain containing 1
UBL4A ubiquitin-like 4A
USP20 ubiquitin specific peptidase 20
WDR3 WD repeat domain 3
ZEB2 zinc finger E-box binding homeobox 2
ZNF140 zinc finger protein 140
ZNF767P zinc finger family member 767, pseudogene