acute myeloid leukemia Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells. (Human Disease Ontology, DOID_9119)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0004808
Similar Terms
Downloads & Tools

Genes

178 genes associated with the acute myeloid leukemia phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 1.00059
CALCR calcitonin receptor 0.928309
MALRD1 MAM and LDL receptor class A domain containing 1 0.919744
SLC51A solute carrier family 51, alpha subunit 0.903602
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 0.884602
ZFAND4 zinc finger, AN1-type domain 4 0.870998
CNTNAP2 contactin associated protein-like 2 0.868241
SMAD6 SMAD family member 6 0.855449
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.844241
KLHL32 kelch-like family member 32 0.844241
PTPRJ protein tyrosine phosphatase, receptor type, J 0.844241
TRAPPC9 trafficking protein particle complex 9 0.844241
APP amyloid beta (A4) precursor protein 0.844241
FRMD5 FERM domain containing 5 0.784165
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.778318
EGFR epidermal growth factor receptor 0.772842
C4ORF45 chromosome 4 open reading frame 45 0.772842
AIG1 androgen-induced 1 0.772842
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 0.772842
C20ORF196 chromosome 20 open reading frame 196 0.772842
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.772842
MAP2 microtubule-associated protein 2 0.772842
RYR2 ryanodine receptor 2 (cardiac) 0.772842
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.772842
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.772842
PXDNL peroxidasin-like 0.726078
CHD9 chromodomain helicase DNA binding protein 9 0.726078
ADAMTSL3 ADAMTS-like 3 0.726078
ERBB4 erb-b2 receptor tyrosine kinase 4 0.726078
PCDH9 protocadherin 9 0.726078
NRXN3 neurexin 3 0.726078
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.726078
ELMO1 engulfment and cell motility 1 0.726078
TPK1 thiamin pyrophosphokinase 1 0.726078
ZNF385D zinc finger protein 385D 0.726078
BMPR1B bone morphogenetic protein receptor, type IB 0.726078
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1 0.726078
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.726078
USP45 ubiquitin specific peptidase 45 0.700393
PAX2 paired box 2 0.697013
FAM207A family with sequence similarity 207, member A 0.693745
CCDC67 coiled-coil domain containing 67 0.690584
FGF12 fibroblast growth factor 12 0.690584
LPA lipoprotein, Lp(a) 0.690584
CADM1 cell adhesion molecule 1 0.690584
NRG3 neuregulin 3 0.690584
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.690584
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.690584
ALPK3 alpha-kinase 3 0.690584
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.690584
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 0.690584
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.690584
PTPRD protein tyrosine phosphatase, receptor type, D 0.690584
AOX2P aldehyde oxidase 2 pseudogene 0.690584
FRMD4A FERM domain containing 4A 0.661809
LINC00540 long intergenic non-protein coding RNA 540 0.661809
DCLK1 doublecortin-like kinase 1 0.661809
ARMC8 armadillo repeat containing 8 0.661809
MEMO1 mediator of cell motility 1 0.661809
SOX5 SRY (sex determining region Y)-box 5 0.661809
COL13A1 collagen, type XIII, alpha 1 0.637546
TFEC transcription factor EC 0.637546
ESRRG estrogen-related receptor gamma 0.637546
LDB2 LIM domain binding 2 0.637546
C6ORF89 chromosome 6 open reading frame 89 0.637546
NGEF neuronal guanine nucleotide exchange factor 0.637546
FBLN1 fibulin 1 0.637546
SEZ6L seizure related 6 homolog (mouse)-like 0.637546
ASS1 argininosuccinate synthase 1 0.637546
EIF3E eukaryotic translation initiation factor 3, subunit E 0.637546
SRD5A3 steroid 5 alpha-reductase 3 0.637546
TBC1D22A TBC1 domain family, member 22A 0.620705
PRR16 proline rich 16 0.616892
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 0.616892
DOPEY1 dopey family member 1 0.616892
MACROD1 MACRO domain containing 1 0.616892
MLPH melanophilin 0.616892
LIMCH1 LIM and calponin homology domains 1 0.616892
KIAA1217 KIAA1217 0.616892
KIF13B kinesin family member 13B 0.616892
UMODL1 uromodulin-like 1 0.599122
FAM71F1 family with sequence similarity 71, member F1 0.599122
AKNAD1 AKNA domain containing 1 0.599122
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 0.599122
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 0.599122
CADM2 cell adhesion molecule 2 0.599122
LOC339862 uncharacterized LOC339862 0.599122
PCDH15 protocadherin-related 15 0.599122
SCHIP1 schwannomin interacting protein 1 0.599122
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.599122
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 0.599122
DFNB31 deafness, autosomal recessive 31 0.585507
UBE2W ubiquitin-conjugating enzyme E2W (putative) 0.584275
ELOVL6 ELOVL fatty acid elongase 6 0.584275
SBF2 SET binding factor 2 0.584275
TMEM132D transmembrane protein 132D 0.584275
ASPA aspartoacylase 0.584275
GLIS3 GLIS family zinc finger 3 0.584275
IQCJ IQ motif containing J 0.584275
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.584275
LUZP2 leucine zipper protein 2 0.584275
LOC728755 uncharacterized LOC728755 0.584275
ASTN2 astrotactin 2 0.584275
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 0.584275
LAMA2 laminin, alpha 2 0.584275
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.584275
NTM neurotrimin 0.584275
SAMD3 sterile alpha motif domain containing 3 0.572823
CFAP61 cilia and flagella associated protein 61 0.572823
FRMD6 FERM domain containing 6 0.572823
SGK1 serum/glucocorticoid regulated kinase 1 0.572823
FAM111B family with sequence similarity 111, member B 0.572823
LINC00578 long intergenic non-protein coding RNA 578 0.572823
KIF16B kinesin family member 16B 0.572823
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.572823
RELN reelin 0.572823
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.572823
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.572823
TMEM165 transmembrane protein 165 0.572823
MACROD2 MACRO domain containing 2 0.572823
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.572823
KIAA1456 KIAA1456 0.572823
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 0.572823
NKAIN3 Na+/K+ transporting ATPase interacting 3 0.572823
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.572823
CLOCK clock circadian regulator 0.572823
C6ORF7 chromosome 6 open reading frame 7 0.572823
LYN LYN proto-oncogene, Src family tyrosine kinase 0.572823
SCUBE1 signal peptide, CUB domain, EGF-like 1 0.572823
CNTN5 contactin 5 0.572823
ARHGAP15 Rho GTPase activating protein 15 0.572823
TOX thymocyte selection-associated high mobility group box 0.572823
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 0.572823
CCDC174 coiled-coil domain containing 174 0.572823
PARD3B par-3 family cell polarity regulator beta 0.572823
PELP1 proline, glutamate and leucine rich protein 1 0.572823
FAM189A1 family with sequence similarity 189, member A1 0.572823
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.572823
SPTBN1 spectrin, beta, non-erythrocytic 1 0.572823
LRP5L low density lipoprotein receptor-related protein 5-like 0.572823
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.572823
CSPP1 centrosome and spindle pole associated protein 1 0.572823
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.572823
FGF6 fibroblast growth factor 6 0.572823
CTIF CBP80/20-dependent translation initiation factor 0.572823
CD38 CD38 molecule 0.572823
SLIT1 slit homolog 1 (Drosophila) 0.572823
MAN2B2 mannosidase, alpha, class 2B, member 2 0.572823
C4ORF22 chromosome 4 open reading frame 22 0.572823
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.572823
PADI3 peptidyl arginine deiminase, type III 0.572823
NUP160 nucleoporin 160kDa 0.572823
CLIC5 chloride intracellular channel 5 0.572823
SNAP25 synaptosomal-associated protein, 25kDa 0.572823
PDZRN3 PDZ domain containing ring finger 3 0.572823
MINOS1-NBL1 MINOS1-NBL1 readthrough 0.572823
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.572823
OSBPL1A oxysterol binding protein-like 1A 0.572823
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.572823
SCN3A sodium channel, voltage gated, type III alpha subunit 0.572823
NXPH1 neurexophilin 1 0.572823
DCAF4 DDB1 and CUL4 associated factor 4 0.572823
ATXN1 ataxin 1 0.572823
IRAK3 interleukin-1 receptor-associated kinase 3 0.572823
THADA thyroid adenoma associated 0.572823
FAM163A family with sequence similarity 163, member A 0.572823
PDCL2 phosducin-like 2 0.531556
CHD2 chromodomain helicase DNA binding protein 2 0.528162
APAF1 apoptotic peptidase activating factor 1 0.522136
IKBIP IKBKB interacting protein 0.522136
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.514254
ZFYVE1 zinc finger, FYVE domain containing 1 0.511765
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.509391
TCF3 transcription factor 3 0.50495
CPM carboxypeptidase M 0.496801
CACHD1 cache domain containing 1 0.496801
NBEA neurobeachin 0.476506
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.470822