actomyosin contractile ring Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells. In animal cells, the contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms beneath the plasma membrane at the mother-bud neck before mitosis. (Gene Ontology, GO_0005826)
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Genes

113 proteins co-occuring with the actomyosin contractile ring cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CASR calcium-sensing receptor 3.82061
PTH parathyroid hormone 2.27519
CARS cysteinyl-tRNA synthetase 2.23297
NPSR1 neuropeptide S receptor 1 2.02782
ANLN anillin, actin binding protein 1.65453
PTHLH parathyroid hormone-like hormone 1.43669
GPRC6A G protein-coupled receptor, class C, group 6, member A 1.33196
GPR182 G protein-coupled receptor 182 1.16747
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.14853
SEPT5 septin 5 1.03729
ECT2 epithelial cell transforming 2 0.938795
GRM1 glutamate receptor, metabotropic 1 0.910647
FMN1 formin 1 0.835515
LPAR5 lysophosphatidic acid receptor 5 0.724365
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.719015
STK38 serine/threonine kinase 38 0.708808
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.665962
FGF23 fibroblast growth factor 23 0.66164
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) 0.646574
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 0.641429
CDC14A cell division cycle 14A 0.632878
CALB2 calbindin 2 0.610778
TJP1 tight junction protein 1 0.607818
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.603174
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.602331
GPR84 G protein-coupled receptor 84 0.600644
CXADR coxsackie virus and adenovirus receptor 0.583849
FLNA filamin A, alpha 0.577581
STC1 stanniocalcin 1 0.575495
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.563017
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 0.536594
FFAR4 free fatty acid receptor 4 0.53454
RGS4 regulator of G-protein signaling 4 0.524294
EXOC1 exocyst complex component 1 0.520206
MYLK3 myosin light chain kinase 3 0.510826
PLK1 polo-like kinase 1 0.509604
TBL1X transducin (beta)-like 1X-linked 0.507977
RACGAP1 Rac GTPase activating protein 1 0.498636
AQP2 aquaporin 2 (collecting duct) 0.479245
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.470807
CALCA calcitonin-related polypeptide alpha 0.465998
MAPK14 mitogen-activated protein kinase 14 0.452029
MYLK myosin light chain kinase 0.444878
TBL1Y transducin (beta)-like 1, Y-linked 0.426318
EVL Enah/Vasp-like 0.421997
CALB1 calbindin 1, 28kDa 0.418077
ALX1 ALX homeobox 1 0.414946
KL klotho 0.40675
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.405971
CA3 carbonic anhydrase III 0.405193
MEN1 multiple endocrine neoplasia I 0.393936
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 0.357467
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.355563
GAST gastrin 0.337373
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.336619
KAZN kazrin, periplakin interacting protein 0.329837
TJP3 tight junction protein 3 0.325702
WIPF1 WAS/WASL interacting protein family, member 1 0.325702
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.323075
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.315586
TRIP10 thyroid hormone receptor interactor 10 0.308122
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.307377
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.307377
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.307004
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.297342
CA2 carbonic anhydrase II 0.295489
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.28846
PVALB parvalbumin 0.285138
TJP2 tight junction protein 2 0.284032
CDC42 cell division cycle 42 0.282926
FFAR2 free fatty acid receptor 2 0.281821
GPR119 G protein-coupled receptor 119 0.27998
TNF tumor necrosis factor 0.277774
BCAP31 B-cell receptor-associated protein 31 0.270068
RHOD ras homolog family member D 0.266774
CGN cingulin 0.264946
EXOSC8 exosome component 8 0.259837
STAMBP STAM binding protein 0.259109
GCM2 glial cells missing homolog 2 (Drosophila) 0.257289
GARS glycyl-tRNA synthetase 0.256561
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.254017
BGLAP bone gamma-carboxyglutamate (gla) protein 0.246407
LRG1 leucine-rich alpha-2-glycoprotein 1 0.244601
KIF14 kinesin family member 14 0.243519
IVL involucrin 0.243519
PRKCD protein kinase C, delta 0.241356
F2 coagulation factor II (thrombin) 0.240276
KRT4 keratin 4, type II 0.236324
CAV1 caveolin 1, caveolae protein, 22kDa 0.229888
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.228108
EXOC7 exocyst complex component 7 0.227752
KMT2E lysine (K)-specific methyltransferase 2E 0.224558
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.22279
MGAM maltase-glucoamylase 0.219969
CDK1 cyclin-dependent kinase 1 0.205059
CHKA choline kinase alpha 0.202346
ALPPL2 alkaline phosphatase, placental-like 2 0.200999
ALPL alkaline phosphatase, liver/bone/kidney 0.200663
ALPP alkaline phosphatase, placental 0.200328
SPP1 secreted phosphoprotein 1 0.196669
PLCG1 phospholipase C, gamma 1 0.1921
SEPT7 septin 7 0.18859
FMNL1 formin-like 1 0.187333
HBG1 hemoglobin, gamma A 0.183935
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.180634
WAS Wiskott-Aldrich syndrome 0.178877
METAP1 methionyl aminopeptidase 1 0.17141
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.168598
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.168349
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.168101
OCLN occludin 0.167856
TRPM5 transient receptor potential cation channel, subfamily M, member 5 0.165231
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.160658