actin filament Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. (Gene Ontology, GO_0005884)
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Genes

745 proteins co-occuring with the actin filament cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TPM1 tropomyosin 1 (alpha) 2.78081
GSN gelsolin 2.69924
VCL vinculin 2.46998
PFN1 profilin 1 2.30657
PFN4 profilin family, member 4 2.27597
PFN2 profilin 2 2.26975
FMN1 formin 1 2.07797
CDC42 cell division cycle 42 2.03144
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.96779
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 1.96356
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.89108
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.89039
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.8897
EZR ezrin 1.88141
CTTN cortactin 1.84361
FSCN1 fascin actin-bundling protein 1 1.82524
MYO5A myosin VA (heavy chain 12, myoxin) 1.82051
CALD1 caldesmon 1 1.81849
FN1 fibronectin 1 1.81579
VASP vasodilator-stimulated phosphoprotein 1.80106
MSN moesin 1.79574
RDX radixin 1.75852
PXN paxillin 1.74003
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.71125
WAS Wiskott-Aldrich syndrome 1.66901
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.63837
DNM2 dynamin 2 1.63005
ACTG1 actin gamma 1 1.61823
PLS1 plastin 1 1.61823
MYLK myosin light chain kinase 1.60534
TJP1 tight junction protein 1 1.57302
NEXN nexilin (F actin binding protein) 1.53726
MYO6 myosin VI 1.53049
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.5113
DNAH8 dynein, axonemal, heavy chain 8 1.4774
FLNA filamin A, alpha 1.46778
ACTB actin, beta 1.46326
LIMK1 LIM domain kinase 1 1.46156
DBN1 drebrin 1 1.46156
TMOD4 tropomodulin 4 (muscle) 1.45307
FSCN3 fascin actin-bundling protein 3, testicular 1.45025
FSCN2 fascin actin-bundling protein 2, retinal 1.44742
ACTA1 actin, alpha 1, skeletal muscle 1.3896
MARCKS myristoylated alanine-rich protein kinase C substrate 1.36637
ACTN4 actinin, alpha 4 1.36472
TMOD1 tropomodulin 1 1.34065
OCLN occludin 1.31465
TMSB4X thymosin beta 4, X-linked 1.2996
NEB nebulin 1.29424
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 1.26022
DNASE1 deoxyribonuclease I 1.25706
CDH5 cadherin 5, type 2 (vascular endothelium) 1.23922
EPB41 erythrocyte membrane protein band 4.1 1.21946
CFL1 cofilin 1 (non-muscle) 1.20292
DIAPH3 diaphanous-related formin 3 1.20086
SSH1 slingshot protein phosphatase 1 1.18389
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 1.1803
MYO1A myosin IA 1.1803
TTN titin 1.16747
ZYX zyxin 1.1644
SCIN scinderin 1.15006
IQGAP1 IQ motif containing GTPase activating protein 1 1.13063
CFL2 cofilin 2 (muscle) 1.12143
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 1.12143
ALB albumin 1.12041
DMD dystrophin 1.08374
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.0812
DSTN destrin (actin depolymerizing factor) 1.07207
TUBA1A tubulin, alpha 1a 1.07207
WASL Wiskott-Aldrich syndrome-like 1.06853
WDR1 WD repeat domain 1 1.06498
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 1.06094
ACTN1 actinin, alpha 1 1.0418
PLEK pleckstrin 1.02629
MGAM maltase-glucoamylase 1.02082
ESPN espin 1.01288
INS insulin 1.003
CD44 CD44 molecule (Indian blood group) 1.00054
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.99956
TNS1 tensin 1 0.999068
VAV1 vav 1 guanine nucleotide exchange factor 0.992693
SEBOX SEBOX homeobox 0.98927
ICAM1 intercellular adhesion molecule 1 0.986342
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.983419
ACTN2 actinin, alpha 2 0.982446
FLNB filamin B, beta 0.97565
UTRN utrophin 0.970814
EPS8 epidermal growth factor receptor pathway substrate 8 0.963588
MYO1B myosin IB 0.951142
BAIAP2 BAI1-associated protein 2 0.951142
NGF nerve growth factor (beta polypeptide) 0.94876
PKN1 protein kinase N1 0.940215
TPM3 tropomyosin 3 0.93785
PLS3 plastin 3 0.933601
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.932658
GC group-specific component (vitamin D binding protein) 0.931245
DAAM1 dishevelled associated activator of morphogenesis 1 0.925135
ANLN anillin, actin binding protein 0.922791
MYO1C myosin IC 0.921386
MYO10 myosin X 0.920449
FLNC filamin C, gamma 0.919982
LRRC16A leucine rich repeat containing 16A 0.917644
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.915309
ANXA2 annexin A2 0.910647
SVIL supervillin 0.909251
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.905067
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.902745
WASH1 WAS protein family homolog 1 0.890707
MPG N-methylpurine-DNA glycosylase 0.874567
WASH7P WAS protein family homolog 7 pseudogene 0.872266
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.871346
WASH6P WAS protein family homolog 6 pseudogene 0.868126
CORO1A coronin, actin binding protein, 1A 0.866746
LIMK2 LIM domain kinase 2 0.864907
SYN1 synapsin I 0.858933
DMTN dematin actin binding protein 0.852961
KLHL2 kelch-like family member 2 0.846073
MYO1E myosin IE 0.843778
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.841941
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.841941
SELL selectin L 0.840105
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.838269
FMN2 formin 2 0.835056
MYLK3 myosin light chain kinase 3 0.827254
RAP2B RAP2B, member of RAS oncogene family 0.827254
TGFB1 transforming growth factor, beta 1 0.823582
SAR1A secretion associated, Ras related GTPase 1A 0.818993
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.816699
ANK1 ankyrin 1, erythrocytic 0.814405
RAB1B RAB1B, member RAS oncogene family 0.813946
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.810735
CORO1C coronin, actin binding protein, 1C 0.8089
TPM2 tropomyosin 2 (beta) 0.804772
ARF3 ADP-ribosylation factor 3 0.803855
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.803396
TMSB10 thymosin beta 10 0.802938
CXCL12 chemokine (C-X-C motif) ligand 12 0.800645
VILL villin-like 0.797895
TAGLN transgelin 0.795145
TNNT2 troponin T type 2 (cardiac) 0.793313
MAP2 microtubule-associated protein 2 0.791939
PALLD palladin, cytoskeletal associated protein 0.789649
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.784156
TMOD3 tropomodulin 3 (ubiquitous) 0.783698
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.783698
MYO7A myosin VIIA 0.779583
ILK integrin-linked kinase 0.774558
JUP junction plakoglobin 0.771819
FHOD1 formin homology 2 domain containing 1 0.771363
TNF tumor necrosis factor 0.766804
MAPT microtubule-associated protein tau 0.766804
MACF1 microtubule-actin crosslinking factor 1 0.766349
SYNPO synaptopodin 0.766349
RHOB ras homolog family member B 0.763162
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.759524
FYN FYN proto-oncogene, Src family tyrosine kinase 0.758161
DSP desmoplakin 0.753623
CD2AP CD2-associated protein 0.748189
FMNL1 formin-like 1 0.738713
HIP1R huntingtin interacting protein 1 related 0.736464
GAS2 growth arrest-specific 2 0.73287
TRIOBP TRIO and F-actin binding protein 0.723919
GJA1 gap junction protein, alpha 1, 43kDa 0.716791
TNNT1 troponin T type 1 (skeletal, slow) 0.715902
SYK spleen tyrosine kinase 0.713682
HRAS Harvey rat sarcoma viral oncogene homolog 0.710579
CXCL8 chemokine (C-X-C motif) ligand 8 0.707039
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.707039
MMP2 matrix metallopeptidase 2 0.703949
LIMA1 LIM domain and actin binding 1 0.699983
PLCG1 phospholipase C, gamma 1 0.697344
EGFR epidermal growth factor receptor 0.696905
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.696465
ALPP alkaline phosphatase, placental 0.695587
NEBL nebulette 0.694709
MYO9B myosin IXB 0.692955
HCK HCK proto-oncogene, Src family tyrosine kinase 0.69164
ALPPL2 alkaline phosphatase, placental-like 2 0.691202
ALPL alkaline phosphatase, liver/bone/kidney 0.690326
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.685954
MAP1B microtubule-associated protein 1B 0.684207
NCKAP1 NCK-associated protein 1 0.683771
COTL1 coactosin-like F-actin binding protein 1 0.679413
ITPKA inositol-trisphosphate 3-kinase A 0.678543
JUN jun proto-oncogene 0.677673
CLDN1 claudin 1 0.675499
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.674196
POMC proopiomelanocortin 0.671159
MCF2 MCF.2 cell line derived transforming sequence 0.668126
ACTG2 actin, gamma 2, smooth muscle, enteric 0.666394
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.666394
ACTA2 actin, alpha 2, smooth muscle, aorta 0.665529
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.662503
PPP1R18 protein phosphatase 1, regulatory subunit 18 0.65259
C5AR1 complement component 5a receptor 1 0.650869
MAPK14 mitogen-activated protein kinase 14 0.65001
COBL cordon-bleu WH2 repeat protein 0.64958
POTEF POTE ankyrin domain family, member F 0.645287
MAP4 microtubule-associated protein 4 0.639717
CLDN7 claudin 7 0.639289
MMP9 matrix metallopeptidase 9 0.638434
DIAPH1 diaphanous-related formin 1 0.638434
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.63544
ARHGAP1 Rho GTPase activating protein 1 0.634159
BCAR1 breast cancer anti-estrogen resistance 1 0.630318
LYN LYN proto-oncogene, Src family tyrosine kinase 0.627761
INF2 inverted formin, FH2 and WH2 domain containing 0.627335
TF transferrin 0.623504
CAPZB capping protein (actin filament) muscle Z-line, beta 0.620954
ITGB4 integrin, beta 4 0.616285
POTEI POTE ankyrin domain family, member I 0.613318
ACT actin-like protein (ACT) gene 0.609086
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.608241
VCAM1 vascular cell adhesion molecule 1 0.60655
ARHGAP35 Rho GTPase activating protein 35 0.60655
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.605706
GSTA4 glutathione S-transferase alpha 4 0.602752
GSTA2 glutathione S-transferase alpha 2 0.602331
TMOD2 tropomodulin 2 (neuronal) 0.601909
NCKAP1L NCK-associated protein 1-like 0.601066
GSTA1 glutathione S-transferase alpha 1 0.599802
SPTB spectrin, beta, erythrocytic 0.597697
PDCL3 phosducin-like 3 0.596435
PTEN phosphatase and tensin homolog 0.596014
DBNL drebrin-like 0.596014
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.595593
GSTA3 glutathione S-transferase alpha 3 0.594332
IL1B interleukin 1, beta 0.593072
TLN1 talin 1 0.589714
KNG1 kininogen 1 0.581758
LCK LCK proto-oncogene, Src family tyrosine kinase 0.579669
PTK2 protein tyrosine kinase 2 0.577164
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.576329
CAV1 caveolin 1, caveolae protein, 22kDa 0.571329
MYBPC3 myosin binding protein C, cardiac 0.570913
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.568832
ACPP acid phosphatase, prostate 0.568416
DAPK3 death-associated protein kinase 3 0.566338
CDK5 cyclin-dependent kinase 5 0.565923
CNN1 calponin 1, basic, smooth muscle 0.565508
LSP1 lymphocyte-specific protein 1 0.563847
PARP1 poly (ADP-ribose) polymerase 1 0.562602
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.562187
MYH11 myosin, heavy chain 11, smooth muscle 0.560943
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.560528
EVL Enah/Vasp-like 0.555973
MLPH melanophilin 0.555973
JMY junction mediating and regulatory protein, p53 cofactor 0.552664
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.551838
RHOQ ras homolog family member Q 0.548947
ITGB7 integrin, beta 7 0.548947
DIAPH2 diaphanous-related formin 2 0.548122
ITGB8 integrin, beta 8 0.548122
ITGB6 integrin, beta 6 0.548122
CTNND1 catenin (cadherin-associated protein), delta 1 0.548122
PFKM phosphofructokinase, muscle 0.542764
ANXA1 annexin A1 0.539883
NCKIPSD NCK interacting protein with SH3 domain 0.539883
CORO1B coronin, actin binding protein, 1B 0.53906
SEPT5 septin 5 0.538238
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.536183
DST dystonin 0.534951
MYBPC2 myosin binding protein C, fast type 0.53413
HSPB6 heat shock protein, alpha-crystallin-related, B6 0.533719
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.531258
RAB27A RAB27A, member RAS oncogene family 0.530438
EDN1 endothelin 1 0.529208
ICAM2 intercellular adhesion molecule 2 0.528798
PTPRD protein tyrosine phosphatase, receptor type, D 0.527979
ARF6 ADP-ribosylation factor 6 0.52716
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.523067
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.521841
GRB2 growth factor receptor-bound protein 2 0.518981
SELPLG selectin P ligand 0.517348
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.517348
DES desmin 0.516124
MYO18A myosin XVIIIA 0.516124
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules 0.512047
AMOT angiomotin 0.510418
WIPF3 WAS/WASL interacting protein family, member 3 0.50635
GFAP glial fibrillary acidic protein 0.50107
CCDC88A coiled-coil domain containing 88A 0.499447
KPTN kaptin (actin binding protein) 0.498636
INSR insulin receptor 0.496205
FOS FBJ murine osteosarcoma viral oncogene homolog 0.494585
EEF1A1P6 eukaryotic translation elongation factor 1 alpha 1 pseudogene 6 0.493775
TIAM1 T-cell lymphoma invasion and metastasis 1 0.490944
ADD2 adducin 2 (beta) 0.488923
ANXA5 annexin A5 0.488115
MARCKSL1 MARCKS-like 1 0.487711
RAVER1 ribonucleoprotein, PTB-binding 1 0.486096
KRT8 keratin 8, type II 0.484483
KRT18 keratin 18, type I 0.48287
TJP2 tight junction protein 2 0.482064
USH1C Usher syndrome 1C (autosomal recessive, severe) 0.481661
MYH10 myosin, heavy chain 10, non-muscle 0.480453
FPR1 formyl peptide receptor 1 0.478038
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.478038
ZHX2 zinc fingers and homeoboxes 2 0.477636
AVP arginine vasopressin 0.474822
VEGFA vascular endothelial growth factor A 0.47442
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 0.474018
FTH1 ferritin, heavy polypeptide 1 0.473617
WASF3 WAS protein family, member 3 0.470406
CGN cingulin 0.468401
MAPK8 mitogen-activated protein kinase 8 0.468401
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.465998
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.465998
FTL ferritin, light polypeptide 0.465198
CDH23 cadherin-related 23 0.463198
CD4 CD4 molecule 0.462398
BDNF brain-derived neurotrophic factor 0.461599
FGF2 fibroblast growth factor 2 (basic) 0.461599
IQGAP2 IQ motif containing GTPase activating protein 2 0.4608
CTSK cathepsin K 0.460001
DOCK8 dedicator of cytokinesis 8 0.458803
SSH2 slingshot protein phosphatase 2 0.458803
CXCR2 chemokine (C-X-C motif) receptor 2 0.458404
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.456809
DOCK2 dedicator of cytokinesis 2 0.456012
BCR breakpoint cluster region 0.454816
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.454816
MYH9 myosin, heavy chain 9, non-muscle 0.454418
LASP1 LIM and SH3 protein 1 0.453621
MYH1 myosin, heavy chain 1, skeletal muscle, adult 0.452825
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.452427
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.451233
AQP2 aquaporin 2 (collecting duct) 0.451233
MYOT myotilin 0.450836
SHROOM3 shroom family member 3 0.449245
MAPK3 mitogen-activated protein kinase 3 0.448451
GAS2L3 growth arrest-specific 2 like 3 0.448451
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.442896
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.442104
CSK c-src tyrosine kinase 0.440916
TAGLN3 transgelin 3 0.44052
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3 0.438937
ADD1 adducin 1 (alpha) 0.43538
CALCA calcitonin-related polypeptide alpha 0.434591
ADD3 adducin 3 (gamma) 0.434196
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.433801
CLMP CXADR-like membrane protein 0.433012
NOS3 nitric oxide synthase 3 (endothelial cell) 0.433012
ADCY2 adenylate cyclase 2 (brain) 0.432618
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.431041
CTGF connective tissue growth factor 0.426318
PLAU plasminogen activator, urokinase 0.42396
LMOD2 leiomodin 2 (cardiac) 0.421604
SYNPO2 synaptopodin 2 0.420036
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.419644
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.419252
CRYAB crystallin, alpha B 0.417685
RTKN rhotekin 0.414946
ERMN ermin, ERM-like protein 0.412992
PRKD1 protein kinase D1 0.412992
TWF2 twinfilin actin binding protein 2 0.41221
SELE selectin E 0.41221
AMOTL2 angiomotin like 2 0.410259
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.410259
SPIRE1 spire-type actin nucleation factor 1 0.409869
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.408309
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.407919
MBP myelin basic protein 0.407529
RHOD ras homolog family member D 0.40675
GMFG glia maturation factor, gamma 0.405971
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.405971
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.404804
F2R coagulation factor II (thrombin) receptor 0.404026
DOCK1 dedicator of cytokinesis 1 0.404026
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.403637
MTSS1 metastasis suppressor 1 0.403248
DOCK5 dedicator of cytokinesis 5 0.402081
GAS2L1 growth arrest-specific 2 like 1 0.401304
PTCH1 patched 1 0.399363
TRIP10 thyroid hormone receptor interactor 10 0.397035
FYB FYN binding protein 0.397035
ARHGAP24 Rho GTPase activating protein 24 0.396648
CSN1S1 casein alpha s1 0.395873
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.395485
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.394323
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.392775
ICAM3 intercellular adhesion molecule 3 0.392001
HIP1 huntingtin interacting protein 1 0.391615
RAB13 RAB13, member RAS oncogene family 0.391228
EPS15 epidermal growth factor receptor pathway substrate 15 0.389682
MAPK11 mitogen-activated protein kinase 11 0.389682
CXCR1 chemokine (C-X-C motif) receptor 1 0.387751
MYO3A myosin IIIA 0.383895
BAIAP2L1 BAI1-associated protein 2-like 1 0.382354
CORO7 coronin 7 0.37966
EPS8L2 EPS8-like 2 0.378891
MYO1D myosin ID 0.377738
NPPA natriuretic peptide A 0.377738
AMOTL1 angiomotin like 1 0.374666
CSF1 colony stimulating factor 1 (macrophage) 0.373899
FABP9 fatty acid binding protein 9, testis 0.372749
SLA2 Src-like-adaptor 2 0.372366
MICALL2 MICAL-like 2 0.371982
GAP43 growth associated protein 43 0.370067
FGF1 fibroblast growth factor 1 (acidic) 0.368919
HSPB1 heat shock 27kDa protein 1 0.367771
LAMP1 lysosomal-associated membrane protein 1 0.367388
TP53 tumor protein p53 0.366241
CNTN1 contactin 1 0.365859
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.365859
S100A4 S100 calcium binding protein A4 0.365095
SPP1 secreted phosphoprotein 1 0.365095
FRMD7 FERM domain containing 7 0.364713
EEA1 early endosome antigen 1 0.362804
MYO5B myosin VB 0.358609
IGF1 insulin-like growth factor 1 (somatomedin C) 0.357467
SDC2 syndecan 2 0.357467
RHOF ras homolog family member F (in filopodia) 0.356324
LYZ lysozyme 0.355944
PHACTR1 phosphatase and actin regulator 1 0.355563
HSPA4 heat shock 70kDa protein 4 0.353662
NF2 neurofibromin 2 (merlin) 0.353662
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 0.352901
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.352522
SMAD2 SMAD family member 2 0.351762
ESAM endothelial cell adhesion molecule 0.351762
CCL2 chemokine (C-C motif) ligand 2 0.350243
CLDN5 claudin 5 0.349105
ARHGAP18 Rho GTPase activating protein 18 0.347967
CLEC9A C-type lectin domain family 9, member A 0.346071
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.346071
GAN gigaxonin 0.343799
FMNL3 formin-like 3 0.343421
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.343421
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.343421
LMOD1 leiomodin 1 (smooth muscle) 0.342285
RAB3D RAB3D, member RAS oncogene family 0.341907
TTC9 tetratricopeptide repeat domain 9 0.341529
CCR7 chemokine (C-C motif) receptor 7 0.339639
PF4 platelet factor 4 0.338884
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.336996
SYNE1 spectrin repeat containing, nuclear envelope 1 0.336241
AMPH amphiphysin 0.336241
ANXA6 annexin A6 0.33511
PLA2G1B phospholipase A2, group IB (pancreas) 0.332848
FHOD3 formin homology 2 domain containing 3 0.332095
EHBP1 EH domain binding protein 1 0.330966
CDKN2A cyclin-dependent kinase inhibitor 2A 0.328332
STARD13 StAR-related lipid transfer (START) domain containing 13 0.327581
POF1B premature ovarian failure, 1B 0.327205
TLN2 talin 2 0.326829
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.323825
CLIC5 chloride intracellular channel 5 0.32195
LEP leptin 0.321575
CAPG capping protein (actin filament), gelsolin-like 0.320451
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.320077
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.319328
HOMER2 homer scaffolding protein 2 0.318953
PI3 peptidase inhibitor 3, skin-derived 0.31783
SI sucrase-isomaltase (alpha-glucosidase) 0.317456
DENND1C DENN/MADD domain containing 1C 0.31596
TPM4 tropomyosin 4 0.315212
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.314465
ITPKB inositol-trisphosphate 3-kinase B 0.312224
PLG plasminogen 0.311851
WIPF2 WAS/WASL interacting protein family, member 2 0.310358
CALCR calcitonin receptor 0.307749
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.306632
FMNL2 formin-like 2 0.305143
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.304399
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.302912
INPPL1 inositol polyphosphate phosphatase-like 1 0.30254
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.301797
SYP synaptophysin 0.298084
RCSD1 RCSD domain containing 1 0.297342
KRAS Kirsten rat sarcoma viral oncogene homolog 0.296601
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.29586
BRWD1 bromodomain and WD repeat domain containing 1 0.295489
PARD6A par-6 family cell polarity regulator alpha 0.294378
CD47 CD47 molecule 0.292897
AVIL advillin 0.292897
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.291417
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 0.291047
EEF2 eukaryotic translation elongation factor 2 0.290678
BTK Bruton agammaglobulinemia tyrosine kinase 0.290308
NCK2 NCK adaptor protein 2 0.289199
THY1 Thy-1 cell surface antigen 0.288829
CNN3 calponin 3, acidic 0.28846
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.288091
LAT2 linker for activation of T cells family, member 2 0.287721
TESK1 testis-specific kinase 1 0.285138
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.284769
LAT linker for activation of T cells 0.284769
HSF4 heat shock transcription factor 4 0.284032
EFNA2 ephrin-A2 0.283295
STAU1 staufen double-stranded RNA binding protein 1 0.282926
CCND1 cyclin D1 0.282189
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.281453
JAK2 Janus kinase 2 0.27998
VWF von Willebrand factor 0.279245
DCTN1 dynactin 1 0.279245
SH2D5 SH2 domain containing 5 0.277774
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.277038
PDLIM4 PDZ and LIM domain 4 0.277038
NES nestin 0.276671
PARVG parvin, gamma 0.276671
ABLIM3 actin binding LIM protein family, member 3 0.276304
SSH3 slingshot protein phosphatase 3 0.275936
CLIP1 CAP-GLY domain containing linker protein 1 0.275569
MKL1 megakaryoblastic leukemia (translocation) 1 0.275569
TYRO3 TYRO3 protein tyrosine kinase 0.273
SHROOM2 shroom family member 2 0.272633
KRT19 keratin 19, type I 0.2719
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.2719
ITGAV integrin, alpha V 0.271167
PHACTR4 phosphatase and actin regulator 4 0.2708
CD34 CD34 molecule 0.268969
FGR FGR proto-oncogene, Src family tyrosine kinase 0.268603
TRIM50 tripartite motif containing 50 0.268603
TFRC transferrin receptor 0.267505
CLDN4 claudin 4 0.267139
MYOM2 myomesin 2 0.267139
RAB35 RAB35, member RAS oncogene family 0.266408
CDK1 cyclin-dependent kinase 1 0.266042
MYO5C myosin VC 0.266042
SSFA2 sperm specific antigen 2 0.264581
GRXCR1 glutaredoxin, cysteine rich 1 0.263485
CCL3 chemokine (C-C motif) ligand 3 0.26312
ANXA8 annexin A8 0.26312
SDC1 syndecan 1 0.26312
PSD pleckstrin and Sec7 domain containing 0.262025
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 0.261296
PTK2B protein tyrosine kinase 2 beta 0.260202
IRS1 insulin receptor substrate 1 0.260202
MYO9A myosin IXA 0.257289
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.257289
PPP6C protein phosphatase 6, catalytic subunit 0.256561
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.255834
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.255107
CAMP cathelicidin antimicrobial peptide 0.254017
APC adenomatous polyposis coli 0.252202
PPP5C protein phosphatase 5, catalytic subunit 0.251114
PLEK2 pleckstrin 2 0.251114
S100A10 S100 calcium binding protein A10 0.250751
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.250026
FNBP4 formin binding protein 4 0.249664
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.248578
CXCL6 chemokine (C-X-C motif) ligand 6 0.24713
CDK5RAP1 CDK5 regulatory subunit associated protein 1 0.244962
ALYREF Aly/REF export factor 0.244962
PPP4C protein phosphatase 4, catalytic subunit 0.244601
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.24424
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.243519
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.242437
F11R F11 receptor 0.241716
PGK1 phosphoglycerate kinase 1 0.241716
SDC4 syndecan 4 0.241716
CCK cholecystokinin 0.240996
EHD2 EH-domain containing 2 0.240996
FKBP15 FK506 binding protein 15, 133kDa 0.240996
NPS neuropeptide S 0.240636
THBS1 thrombospondin 1 0.240276
NCAM1 neural cell adhesion molecule 1 0.239557
SEPT2 septin 2 0.239197
MYOCD myocardin 0.238837
PARVA parvin, alpha 0.238119
PDGFB platelet-derived growth factor beta polypeptide 0.236324
AHNAK AHNAK nucleoprotein 0.235607
BMP2 bone morphogenetic protein 2 0.235249
GPHA2 glycoprotein hormone alpha 2 0.235249
PCDH15 protocadherin-related 15 0.234891
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.233101
GRP gastrin-releasing peptide 0.233101
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.232744
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.231315
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.230601
F8 coagulation factor VIII, procoagulant component 0.228819
CAPN2 calpain 2, (m/II) large subunit 0.228108
FCHSD2 FCH and double SH3 domains 2 0.225976
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.225622
CADM1 cell adhesion molecule 1 0.225622
ACTC1 actin, alpha, cardiac muscle 1 0.225267
ATP11A ATPase, class VI, type 11A 0.224913
RELN reelin 0.224558
CCL21 chemokine (C-C motif) ligand 21 0.224204
DFNB31 deafness, autosomal recessive 31 0.22385
ERBB2 erb-b2 receptor tyrosine kinase 2 0.22385
TIMP1 TIMP metallopeptidase inhibitor 1 0.223497
S100A11 S100 calcium binding protein A11 0.223497
CORO2B coronin, actin binding protein, 2B 0.223143
MESDC1 mesoderm development candidate 1 0.223143
ISL1 ISL LIM homeobox 1 0.22279
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.222436
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.222436
MYO19 myosin XIX 0.222083
HSPA8 heat shock 70kDa protein 8 0.222083
GPR174 G protein-coupled receptor 174 0.22173
SHROOM4 shroom family member 4 0.22173
ALDOC aldolase C, fructose-bisphosphate 0.221378
CLDN3 claudin 3 0.220673
CCIN calicin 0.219969
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.218212
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.217861
CDC42SE1 CDC42 small effector 1 0.217861
RAP1A RAP1A, member of RAS oncogene family 0.217511
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.21681
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.21646
NT5E 5'-nucleotidase, ecto (CD73) 0.215412
CCL19 chemokine (C-C motif) ligand 19 0.213669
EPS8L3 EPS8-like 3 0.213322
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.213322
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.21124
TSPO translocator protein (18kDa) 0.21124
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.210894
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.209858
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.209169
PCSK9 proprotein convertase subtilisin/kexin type 9 0.208825
PKD1P6 polycystic kidney disease 1 (autosomal dominant) pseudogene 6 0.208481
TNNI3 troponin I type 3 (cardiac) 0.208481
LATS1 large tumor suppressor kinase 1 0.207794
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0.206766
SYN3 synapsin III 0.205399
CRYAA crystallin, alpha A 0.205399
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.203699
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.203022
CDK14 cyclin-dependent kinase 14 0.203022
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.201672
CDC42SE2 CDC42 small effector 2 0.200999
GAS2L2 growth arrest-specific 2 like 2 0.200663
SNORA29 small nucleolar RNA, H/ACA box 29 0.200663
KAT2B K(lysine) acetyltransferase 2B 0.199993
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.199993
TNS2 tensin 2 0.199659
KRTAP1-5 keratin associated protein 1-5 0.199325
FIZ1 FLT3-interacting zinc finger 1 0.198991
PRF1 perforin 1 (pore forming protein) 0.198658
KRTAP2-1 keratin associated protein 2-1 0.198325
SOD2 superoxide dismutase 2, mitochondrial 0.198325
KRTAP2-3 keratin associated protein 2-3 0.198325
BIN3 bridging integrator 3 0.197662
RAI14 retinoic acid induced 14 0.19733
SORBS1 sorbin and SH3 domain containing 1 0.196669
OCSTAMP osteoclast stimulatory transmembrane protein 0.195681
HBA1 hemoglobin, alpha 1 0.195353
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.195025
ODC1 ornithine decarboxylase 1 0.194698
FNBP1 formin binding protein 1 0.192423
ESR1 estrogen receptor 1 0.192423
LMO7 LIM domain 7 0.192423
TLR4 toll-like receptor 4 0.192423
TNC tenascin C 0.1921
MADD MAP-kinase activating death domain 0.191777
RBSN rabenosyn, RAB effector 0.191777
SPIRE2 spire-type actin nucleation factor 2 0.191456
KIAA0101 KIAA0101 0.191135
HBA2 hemoglobin, alpha 2 0.190495
ENO2 enolase 2 (gamma, neuronal) 0.189857
CAST calpastatin 0.189857
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.189539
KLHL20 kelch-like family member 20 0.189539
ARC activity-regulated cytoskeleton-associated protein 0.189539
RHPN1 rhophilin, Rho GTPase binding protein 1 0.189222
STRIP2 striatin interacting protein 2 0.18702
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.186397
ABLIM1 actin binding LIM protein 1 0.186397
DLC1 DLC1 Rho GTPase activating protein 0.185777
GAS7 growth arrest-specific 7 0.185777
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.185469
WIPF1 WAS/WASL interacting protein family, member 1 0.184853
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 0.183935
PKM pyruvate kinase, muscle 0.183631
PKLR pyruvate kinase, liver and RBC 0.183328
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 0.183025
DNM1 dynamin 1 0.183025
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 0.182122
SHANK3 SH3 and multiple ankyrin repeat domains 3 0.181823
HDAC6 histone deacetylase 6 0.181524
GPHN gephyrin 0.18093
NCK1 NCK adaptor protein 1 0.180045
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.179752
AFAP1L1 actin filament associated protein 1-like 1 0.179752
MRC1 mannose receptor, C type 1 0.179459
MPO myeloperoxidase 0.179459
CCR1 chemokine (C-C motif) receptor 1 0.179167
ZRANB1 zinc finger, RAN-binding domain containing 1 0.177724
AKAP12 A kinase (PRKA) anchor protein 12 0.177154
SYN2 synapsin II 0.176305
IL1A interleukin 1, alpha 0.176305
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.176024
EIF3A eukaryotic translation initiation factor 3, subunit A 0.176024
PDLIM3 PDZ and LIM domain 3 0.174911
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.174635
GJB1 gap junction protein, beta 1, 32kDa 0.174635
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.174635
IL2 interleukin 2 0.174361
KLHL1 kelch-like family member 1 0.173543
RND1 Rho family GTPase 1 0.173003
OCRL oculocerebrorenal syndrome of Lowe 0.173003
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 0.172735
CD79A CD79a molecule, immunoglobulin-associated alpha 0.172735
IGLC3 immunoglobulin lambda constant 3 (Kern-Oz+ marker) 0.171937
KIF23 kinesin family member 23 0.171673
STX3 syntaxin 3 0.171149
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.170629
ECT2 epithelial cell transforming 2 0.170629
CD302 CD302 molecule 0.169859
GLB1 galactosidase, beta 1 0.169859
RRAS related RAS viral (r-ras) oncogene homolog 0.16935
DGCR6L DiGeorge syndrome critical region gene 6-like 0.168598
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.168349
MYO15A myosin XVA 0.167856
PFDN5 prefoldin subunit 5 0.167611
RHOU ras homolog family member U 0.167366
EPHA4 EPH receptor A4 0.167125
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.165932
PTH parathyroid hormone 0.165697
PNKD paroxysmal nonkinesigenic dyskinesia 0.165697
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.165463
MAPK1 mitogen-activated protein kinase 1 0.165231
ADGRG3 adhesion G protein-coupled receptor G3 0.16477
CTTNBP2 cortactin binding protein 2 0.16477
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.163865
STRIP1 striatin interacting protein 1 0.163865
KRT14 keratin 14, type I 0.163865
FAT2 FAT atypical cadherin 2 0.163865
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.16342
IL6 interleukin 6 0.1632
RALB v-ral simian leukemia viral oncogene homolog B 0.16298
FRMPD4 FERM and PDZ domain containing 4 0.16298
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.16298
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.162763
FCHSD1 FCH and double SH3 domains 1 0.162117
RET ret proto-oncogene 0.161693
EFS embryonal Fyn-associated substrate 0.161484
PRL prolactin 0.161484
PGM5 phosphoglucomutase 5 0.160658
LAYN layilin 0.160053
LPO lactoperoxidase 0.159658
AATF apoptosis antagonizing transcription factor 0.159462
SEPT6 septin 6 0.159462
KBTBD13 kelch repeat and BTB (POZ) domain containing 13 0.159268
PLCD1 phospholipase C, delta 1 0.158692
FGF7 fibroblast growth factor 7 0.158502
BAX BCL2-associated X protein 0.158315
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.158315
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.157943
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.157397
MAPK4 mitogen-activated protein kinase 4 0.157218
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.157039
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.156342