acemetacin-7442 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the acemetacin-7442 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AKAP17A A kinase (PRKA) anchor protein 17A
AKR1C2 aldo-keto reductase family 1, member C2
AKT2 v-akt murine thymoma viral oncogene homolog 2
APAF1 apoptotic peptidase activating factor 1
ARNT aryl hydrocarbon receptor nuclear translocator
BAIAP2 BAI1-associated protein 2
BRD4 bromodomain containing 4
CBX2 chromobox homolog 2
CCDC88C coiled-coil domain containing 88C
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CTAGE9 CTAGE family, member 9
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DGAT1 diacylglycerol O-acyltransferase 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DST dystonin
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ECE1 endothelin converting enzyme 1
EED embryonic ectoderm development
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EPHB4 EPH receptor B4
EPN2 epsin 2
EXOC7 exocyst complex component 7
GCHFR GTP cyclohydrolase I feedback regulator
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
HAUS5 HAUS augmin-like complex, subunit 5
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIST1H2AM histone cluster 1, H2am
HIST1H2BJ histone cluster 1, H2bj
HTT huntingtin
IL15RA interleukin 15 receptor, alpha
INADL InaD-like (Drosophila)
INPP1 inositol polyphosphate-1-phosphatase
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IRS2 insulin receptor substrate 2
ITPK1 inositol-tetrakisphosphate 1-kinase
JAG1 jagged 1
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KIAA0930 KIAA0930
KIF13B kinesin family member 13B
KRIT1 KRIT1, ankyrin repeat containing
LAMP1 lysosomal-associated membrane protein 1
LOC730101 uncharacterized LOC730101
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAPK14 mitogen-activated protein kinase 14
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MET MET proto-oncogene, receptor tyrosine kinase
MKL1 megakaryoblastic leukemia (translocation) 1
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MOCS1 molybdenum cofactor synthesis 1
MT1G metallothionein 1G
MYT1 myelin transcription factor 1
NBL1 neuroblastoma 1, DAN family BMP antagonist
NKX3-2 NK3 homeobox 2
PDK2 pyruvate dehydrogenase kinase, isozyme 2
POFUT1 protein O-fucosyltransferase 1
POLL polymerase (DNA directed), lambda
PPAP2B phosphatidic acid phosphatase type 2B
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP6R2 protein phosphatase 6, regulatory subunit 2
PTCH1 patched 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PVT1 Pvt1 oncogene (non-protein coding)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RANBP3 RAN binding protein 3
RARG retinoic acid receptor, gamma
RIMS2 regulating synaptic membrane exocytosis 2
RPL35A ribosomal protein L35a
RUFY3 RUN and FYVE domain containing 3
SAPCD1 suppressor APC domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SDC3 syndecan 3
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SETD4 SET domain containing 4
SH3BP2 SH3-domain binding protein 2
SIK2 salt-inducible kinase 2
SIRT3 sirtuin 3
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SUGP1 SURP and G patch domain containing 1
SYNRG synergin, gamma
SYT17 synaptotagmin XVII
TBC1D13 TBC1 domain family, member 13
TFDP1 transcription factor Dp-1
TOM1 target of myb1 (chicken)
TSC22D2 TSC22 domain family, member 2
VEZT vezatin, adherens junctions transmembrane protein
ZER1 zyg-11 related, cell cycle regulator
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ALPK1 alpha-kinase 1
ANXA1 annexin A1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ATAD3A ATPase family, AAA domain containing 3A
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C17ORF70 chromosome 17 open reading frame 70
C6ORF47 chromosome 6 open reading frame 47
C9ORF40 chromosome 9 open reading frame 40
CASC3 cancer susceptibility candidate 3
CBY1 chibby homolog 1 (Drosophila)
CDK3 cyclin-dependent kinase 3
CHMP7 charged multivesicular body protein 7
CHST10 carbohydrate sulfotransferase 10
CIC capicua transcriptional repressor
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DUSP8 dual specificity phosphatase 8
DYSF dysferlin
EGLN3 egl-9 family hypoxia-inducible factor 3
ELOVL4 ELOVL fatty acid elongase 4
FAM131A family with sequence similarity 131, member A
FBXO2 F-box protein 2
FGD6 FYVE, RhoGEF and PH domain containing 6
FKBP10 FK506 binding protein 10, 65 kDa
GATA6 GATA binding protein 6
GPATCH3 G patch domain containing 3
GPR19 G protein-coupled receptor 19
HIST1H2AE histone cluster 1, H2ae
HIST1H3B histone cluster 1, H3b
HLA-J major histocompatibility complex, class I, J (pseudogene)
IFT22 intraflagellar transport 22
KAT2A K(lysine) acetyltransferase 2A
KAT2B K(lysine) acetyltransferase 2B
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIF18B kinesin family member 18B
KIFAP3 kinesin-associated protein 3
KREMEN2 kringle containing transmembrane protein 2
KRT13 keratin 13, type I
LAS1L LAS1-like (S. cerevisiae)
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMBR1L limb development membrane protein 1-like
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC390998 ribosomal protein L10 pseudogene
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC37A2 leucine rich repeat containing 37, member A2
MBTD1 mbt domain containing 1
MRPL44 mitochondrial ribosomal protein L44
MXD3 MAX dimerization protein 3
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OSMR oncostatin M receptor
PCDHB3 protocadherin beta 3
PGPEP1 pyroglutamyl-peptidase I
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLXNA3 plexin A3
PPP6R1 protein phosphatase 6, regulatory subunit 1
PRICKLE3 prickle homolog 3 (Drosophila)
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PYCRL pyrroline-5-carboxylate reductase-like
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPAP1 RNA polymerase II associated protein 1
SCD5 stearoyl-CoA desaturase 5
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SETD1B SET domain containing 1B
SGK1 serum/glucocorticoid regulated kinase 1
SHPK sedoheptulokinase
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SMG9 SMG9 nonsense mediated mRNA decay factor
SP140L SP140 nuclear body protein-like
STARD13 StAR-related lipid transfer (START) domain containing 13
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TEAD3 TEA domain family member 3
THOP1 thimet oligopeptidase 1
TMC7 transmembrane channel-like 7
TMEM209 transmembrane protein 209
TMEM53 transmembrane protein 53
TMSB15A thymosin beta 15a
TNS2 tensin 2
TUBA3C tubulin, alpha 3c
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VPS9D1 VPS9 domain containing 1
VSIG10 V-set and immunoglobulin domain containing 10
WDR60 WD repeat domain 60
WDR76 WD repeat domain 76
ZNF205 zinc finger protein 205
ZNF250 zinc finger protein 250
ZNF266 zinc finger protein 266
ZNF767P zinc finger family member 767, pseudogene