absent roof plate Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of the single row of specialized glial cells that occupies the dorsal midline of the developing neural tube along the entire anterior-posterior axis; the roof plate serves as a critical embryonic signaling center for the organization of dorsal neuronal cell types, and acts as a barrier preventing axons and cells migrating across the dorsal midline (Mammalian Phenotype Ontology, MP_0000924)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000924
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1 gene mutations causing the absent roof plate phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
PDGFRA platelet-derived growth factor receptor, alpha polypeptide