absent pro-b cells Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of the progenitor cells of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but are not yet fully committed to the B cell lineage until the expression of PAX5 occurs (Mammalian Phenotype Ontology, MP_0008187)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008187
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Genes

4 gene mutations causing the absent pro-b cells phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
IKZF1 IKAROS family zinc finger 1 (Ikaros)
PAX5 paired box 5
RAG1 recombination activating gene 1
TCF3 transcription factor 3