absent primitive endoderm Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of the transient thin monolayer of cuboidal cells that comprise the lower layer of the bilaminar embryonic disk; the hypoblast cells contribute to several extraembryonic structures, but do not contribute to the embryo (Mammalian Phenotype Ontology, MP_0011185)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011185
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Genes

3 gene mutations causing the absent primitive endoderm phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CXXC1 CXXC finger protein 1
FGFR2 fibroblast growth factor receptor 2
NANOG Nanog homeobox