|Dataset||MPO Gene-Phenotype Associations|
|Category||disease or phenotype associations|
|Description||absence of the horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann's organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue (Mammalian Phenotype Ontology, MP_0004388)|
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4 gene mutations causing the absent prechordal plate phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.