absent prechordal plate Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of the horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann's organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue (Mammalian Phenotype Ontology, MP_0004388)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004388
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Genes

4 gene mutations causing the absent prechordal plate phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CNBP CCHC-type zinc finger, nucleic acid binding protein
NODAL nodal growth differentiation factor
SSBP3 single stranded DNA binding protein 3
TDGF1 teratocarcinoma-derived growth factor 1