absent pre-b cells Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of the cells in the B lymphocyte lineage that have undergone VDJ rearrangement of the immunoglobulin heavy chain and are in the process of V-J rearrangement of the light chain: these cells express mu heavy chain on the cell surface (Mammalian Phenotype Ontology, MP_0000238)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000238
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Genes

9 gene mutations causing the absent pre-b cells phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD79A CD79a molecule, immunoglobulin-associated alpha
CREBBP CREB binding protein
CYCS cytochrome c, somatic
IKZF1 IKAROS family zinc finger 1 (Ikaros)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
SOX4 SRY (sex determining region Y)-box 4
SYK spleen tyrosine kinase
TCF3 transcription factor 3
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6