absent nodal flow Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of the leftward movement of extra-embryonic fluid at the ventral node; nodal flow is autonomously generated by the rotation of cilia that are tilted toward the posterior on cells of the ventral node and is the central process in symmetry breaking on the left-right axis; when nodal cilia are immotile or absent, nodal flow does not occur (Mammalian Phenotype Ontology, MP_0012093)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0012093
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Genes

5 gene mutations causing the absent nodal flow phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
DNAH11 dynein, axonemal, heavy chain 11
FOXJ1 forkhead box J1
KIF3A kinesin family member 3A
MKS1 Meckel syndrome, type 1
NOTO notochord homeobox