absent metanephric mesenchyme Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing metanephros; normally, interactions between the ureteric bud and the metanephric mesenchyme lead to the initiation of outgrowth and repetitive branching of the UB that ultimately generates the definitive renal collecting system and induces formation of renal vesicles from the mesenchyme tissue (Mammalian Phenotype Ontology, MP_0011387)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011387
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Genes

3 gene mutations causing the absent metanephric mesenchyme phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BMP7 bone morphogenetic protein 7
LRP4 low density lipoprotein receptor-related protein 4
OSR1 odd-skipped related transciption factor 1