absent marginal zone b cells Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of CD23-negative, CD21-positive B cells of the marginal zone of the spleen expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL (Mammalian Phenotype Ontology, MP_0008183)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008183
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Genes

7 gene mutations causing the absent marginal zone b cells phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
DOCK8 dedicator of cytokinesis 8
LTA lymphotoxin alpha
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NKX2-3 NK2 homeobox 3
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
ZEB1 zinc finger E-box binding homeobox 1