absent lymph nodes Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of the oval or bean shaped bodies located along the lymphatic system that consist of densely packed lymphocytes, lymph fluid and connective tissue; these are the sites where acquired immune responses are launched (Mammalian Phenotype Ontology, MP_0008024)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008024
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Genes

14 gene mutations causing the absent lymph nodes phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
COL10A1 collagen, type X, alpha 1
CXCR5 chemokine (C-X-C motif) receptor 5
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL7 interleukin 7
JAK3 Janus kinase 3
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
MAP3K14 mitogen-activated protein kinase kinase kinase 14
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RORC RAR-related orphan receptor C
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11