absent immature b cells Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity (Mammalian Phenotype Ontology, MP_0008213)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008213
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Genes

14 gene mutations causing the absent immature b cells phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CARD11 caspase recruitment domain family, member 11
CD79A CD79a molecule, immunoglobulin-associated alpha
CREBBP CREB binding protein
CYCS cytochrome c, somatic
DCLRE1C DNA cross-link repair 1C
IGHM immunoglobulin heavy constant mu
IKZF1 IKAROS family zinc finger 1 (Ikaros)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RAG1 recombination activating gene 1
SOX4 SRY (sex determining region Y)-box 4
SYK spleen tyrosine kinase
TCF3 transcription factor 3
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6