absent embryonic epiblast Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of the transient structure derived from the inner cell mass which lies above the hypoblast; the epiblast tissue gives rise to the three primary germ layers (ectoderm, definitive endoderm, and mesoderm) and to the extraembryonic mesoderm of the visceral yolk sac, the allantois, and the amnion (Mammalian Phenotype Ontology, MP_0011184)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011184
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11 gene mutations causing the absent embryonic epiblast phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CDC42 cell division cycle 42
CXXC1 CXXC finger protein 1
GTF2I general transcription factor IIi
KIF16B kinesin family member 16B
LIN9 lin-9 DREAM MuvB core complex component
NANOG Nanog homeobox
NBN nibrin
SOX2 SRY (sex determining region Y)-box 2
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TXNRD1 thioredoxin reductase 1
UBA3 ubiquitin-like modifier activating enzyme 3