absent apical ectodermal ridge Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description missing the multilayered ectodermal region at the tip of a limb bud necessary for the proper development of the underlying mesenchyme (Mammalian Phenotype Ontology, MP_0001677)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001677
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Genes

4 gene mutations causing the absent apical ectodermal ridge phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
FGFR2 fibroblast growth factor receptor 2
GPR161 G protein-coupled receptor 161
LRP6 low density lipoprotein receptor-related protein 6
TP63 tumor protein p63