abnormality of thyroid physiology Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An abnormal functionality of the thyroid gland. (Human Phenotype Ontology, HP_0002926)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0002926
Similar Terms
Downloads & Tools

Genes

120 genes associated with the abnormality of thyroid physiology phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
C1QTNF6 C1q and tumor necrosis factor related protein 6 1.57499
TSHR thyroid stimulating hormone receptor 1.54145
C6ORF10 chromosome 6 open reading frame 10 1.49739
SLAMF6 SLAM family member 6 1.34259
HLA-J major histocompatibility complex, class I, J (pseudogene) 1.18249
TCF19 transcription factor 19 1.15352
CCHCR1 coiled-coil alpha-helical rod protein 1 1.12901
MUC22 mucin 22 1.1097
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 1.1097
FCRL3 Fc receptor-like 3 1.09351
SH2B3 SH2B adaptor protein 3 1.00982
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 1.00059
ATXN2 ataxin 2 0.99234
FGFR1OP FGFR1 oncogene partner 0.861381
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.849662
MOG myelin oligodendrocyte glycoprotein 0.814376
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 0.792067
CEP128 centrosomal protein 128kDa 0.77446
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.771534
VAV3 vav 3 guanine nucleotide exchange factor 0.733286
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.719731
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.639483
CNTNAP2 contactin associated protein-like 2 0.636399
TG thyroglobulin 0.584959
FCRL1 Fc receptor-like 1 0.566316
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.508704
TNF tumor necrosis factor 0.502291
NELFE negative elongation factor complex member E 0.467973
SLA Src-like-adaptor 0.446209
RNASET2 ribonuclease T2 0.423749
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor 0.416322
CD5L CD5 molecule-like 0.415794
HLA-B major histocompatibility complex, class I, B 0.415539
PDE8B phosphodiesterase 8B 0.413807
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.413807
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.413807
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.41169
C6ORF15 chromosome 6 open reading frame 15 0.410331
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.408206
INSR insulin receptor 0.406588
FCRL2 Fc receptor-like 2 0.405782
CFB complement factor B 0.404539
RECQL5 RecQ protein-like 5 0.404424
ASIC2 acid sensing (proton gated) ion channel 2 0.40409
ZNF804B zinc finger protein 804B 0.40409
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.40409
MTF1 metal-regulatory transcription factor 1 0.402177
HCG22 HLA complex group 22 0.401767
LOC100506999 uncharacterized LOC100506999 0.399886
TSHZ2 teashirt zinc finger homeobox 2 0.399886
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 0.398093
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 0.397531
CALD1 caldesmon 1 0.397252
PFKP phosphofructokinase, platelet 0.396981
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.396463
RAB20 RAB20, member RAS oncogene family 0.39507
CLECL1 C-type lectin-like 1 0.39507
CALN1 calneuron 1 0.394651
PRKCE protein kinase C, epsilon 0.393867
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.39264
LACTB lactamase, beta 0.392247
ZDHHC17 zinc finger, DHHC-type containing 17 0.392247
THSD4 thrombospondin, type I, domain containing 4 0.391503
PCDH15 protocadherin-related 15 0.391503
GNG2 guanine nucleotide binding protein (G protein), gamma 2 0.389544
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.389366
VAV1 vav 1 guanine nucleotide exchange factor 0.389337
SNAP47 synaptosomal-associated protein, 47kDa 0.38925
AGER advanced glycosylation end product-specific receptor 0.388686
BTNL2 butyrophilin-like 2 0.388393
FOXE1 forkhead box E1 0.386627
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 0.386091
FKTN fukutin 0.385832
TASP1 taspase, threonine aspartase, 1 0.384822
VTI1A vesicle transport through interaction with t-SNAREs 1A 0.384155
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.383955
RBP4 retinol binding protein 4, plasma 0.383715
VMP1 vacuole membrane protein 1 0.383501
TTLL6 tubulin tyrosine ligase-like family member 6 0.382881
CAPZB capping protein (actin filament) muscle Z-line, beta 0.382681
TRIM15 tripartite motif containing 15 0.382681
WISP1 WNT1 inducible signaling pathway protein 1 0.382561
STAC SH3 and cysteine rich domain 0.382498
RTKN2 rhotekin 2 0.38229
ANKRD26 ankyrin repeat domain 26 0.382269
DFNB31 deafness, autosomal recessive 31 0.381743
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 0.381469
CASC15 cancer susceptibility candidate 15 (non-protein coding) 0.381469
CLDN2 claudin 2 0.380899
IL2RA interleukin 2 receptor, alpha 0.380899
KIRREL3 kin of IRRE like 3 (Drosophila) 0.380715
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.380715
DCBLD1 discoidin, CUB and LCCL domain containing 1 0.380533
KLHL29 kelch-like family member 29 0.380533
CHL1 cell adhesion molecule L1-like 0.380533
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.380354
URI1 URI1, prefoldin-like chaperone 0.380177
CSMD3 CUB and Sushi multiple domains 3 0.380124
OPCML opioid binding protein/cell adhesion molecule-like 0.37966
DAAM1 dishevelled associated activator of morphogenesis 1 0.379163
RIN2 Ras and Rab interactor 2 0.379082
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.378843
TNNT3 troponin T type 3 (skeletal, fast) 0.378685
CNTN4 contactin 4 0.378529
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.378376
GPC5 glypican 5 0.378376
ERICH1 glutamate-rich 1 0.377778
PDE10A phosphodiesterase 10A 0.377633
ERCC5 excision repair cross-complementation group 5 0.377208
MACROD2 MACRO domain containing 2 0.376796
MAN1C1 mannosidase, alpha, class 1C, member 1 0.376661
KALRN kalirin, RhoGEF kinase 0.370686
RNF144A ring finger protein 144A 0.36623
HCG9 HLA complex group 9 (non-protein coding) 0.359722
CIPC CLOCK-interacting pacemaker 0.352924
ACSF3 acyl-CoA synthetase family member 3 0.352201
IRF2BPL interferon regulatory factor 2 binding protein-like 0.345167
CLEC16A C-type lectin domain family 16, member A 0.344853
LEMD2 LEM domain containing 2 0.344853
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.344755