abnormality of the urinary system physiology Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0011277
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Genes

164 genes associated with the abnormality of the urinary system physiology phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.6419
HBB hemoglobin, beta 0.944852
PLA2R1 phospholipase A2 receptor 1, 180kDa 0.57444
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.395531
OR51F1 olfactory receptor, family 51, subfamily F, member 1 (gene/pseudogene) 0.390575
OR51B5 olfactory receptor, family 51, subfamily B, member 5 0.369903
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.356494
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.356287
MAP3K15 mitogen-activated protein kinase kinase kinase 15 0.342577
AGXT2 alanine--glyoxylate aminotransferase 2 0.342268
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 0.340922
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.335411
CFH complement factor H 0.333254
UMOD uromodulin 0.331682
MYH9 myosin, heavy chain 9, non-muscle 0.330723
ATXN2 ataxin 2 0.327786
SHROOM3 shroom family member 3 0.327528
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 0.323112
HORMAD2 HORMA domain containing 2 0.322441
ALMS1P Alstrom syndrome 1 pseudogene 0.322441
RNF185 ring finger protein 185 0.304453
LIMK2 LIM domain kinase 2 0.302921
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.289034
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.288311
MED23 mediator complex subunit 23 0.286271
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.286271
LARGE like-glycosyltransferase 0.285115
GPC5 glypican 5 0.280696
CDH13 cadherin 13 0.275192
GCKR glucokinase (hexokinase 4) regulator 0.275192
CHN2 chimerin 2 0.272392
SASH1 SAM and SH3 domain containing 1 0.271604
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 0.270732
ZNF804A zinc finger protein 804A 0.267658
GRIK2 glutamate receptor, ionotropic, kainate 2 0.261917
PVT1 Pvt1 oncogene (non-protein coding) 0.259433
CARS cysteinyl-tRNA synthetase 0.254463
SORBS1 sorbin and SH3 domain containing 1 0.250004
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.246422
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.244857
OR51E2 olfactory receptor, family 51, subfamily E, member 2 0.244318
ELMO1 engulfment and cell motility 1 0.242833
MAST2 microtubule associated serine/threonine kinase 2 0.240834
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.24007
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 0.24007
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.238895
PLXNA4 plexin A4 0.238895
UNC5C unc-5 homolog C (C. elegans) 0.238783
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 0.236843
PARK2 parkin RBR E3 ubiquitin protein ligase 0.235935
ADAM23 ADAM metallopeptidase domain 23 0.235935
PLEKHA6 pleckstrin homology domain containing, family A member 6 0.235935
C6ORF10 chromosome 6 open reading frame 10 0.235093
LOC100132891 0.234306
FAM53B family with sequence similarity 53, member B 0.234306
PCNT pericentrin 0.234306
LOC100294145 uncharacterized LOC100294145 0.234306
TBC1D14 TBC1 domain family, member 14 0.232027
SMYD3 SET and MYND domain containing 3 0.231238
PDE5A phosphodiesterase 5A, cGMP-specific 0.231005
FGD4 FYVE, RhoGEF and PH domain containing 4 0.231005
HSPA4L heat shock 70kDa protein 4-like 0.231005
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.231005
PRRC2A proline-rich coiled-coil 2A 0.229394
DNAH7 dynein, axonemal, heavy chain 7 0.229394
CIAPIN1 cytokine induced apoptosis inhibitor 1 0.228863
FAM134B family with sequence similarity 134, member B 0.228863
SLC35F3 solute carrier family 35, member F3 0.228863
STON2 stonin 2 0.227318
MAML2 mastermind-like 2 (Drosophila) 0.227318
TTC21A tetratricopeptide repeat domain 21A 0.227318
WWOX WW domain containing oxidoreductase 0.225935
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.22437
MTMR10 myotubularin related protein 10 0.223912
MEIS1 Meis homeobox 1 0.223912
MED27 mediator complex subunit 27 0.223912
P3H2 prolyl 3-hydroxylase 2 0.223183
HNMT histamine N-methyltransferase 0.223183
ZDHHC21 zinc finger, DHHC-type containing 21 0.222833
MARCH11 membrane-associated ring finger (C3HC4) 11 0.222492
NCALD neurocalcin delta 0.222492
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa 0.22216
CLYBL citrate lyase beta like 0.22216
TSHZ2 teashirt zinc finger homeobox 2 0.22152
STAC SH3 and cysteine rich domain 0.22152
ISM1 isthmin 1, angiogenesis inhibitor 0.220615
IL12RB1 interleukin 12 receptor, beta 1 0.220356
DNAH11 dynein, axonemal, heavy chain 11 0.220327
SLC14A2 solute carrier family 14 (urea transporter), member 2 0.220046
CD48 CD48 molecule 0.21977
NTN1 netrin 1 0.219661
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.2195
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.218976
FGF12 fibroblast growth factor 12 0.218547
OR2L13 olfactory receptor, family 2, subfamily L, member 13 0.218155
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.217988
HPS1 Hermansky-Pudlak syndrome 1 0.217521
OR13D1 olfactory receptor, family 13, subfamily D, member 1 0.217294
MYO5B myosin VB 0.216916
SMIM23 small integral membrane protein 23 0.216635
PRKCH protein kinase C, eta 0.216422
TMEM63C transmembrane protein 63C 0.216213
NRXN1 neurexin 1 0.216172
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.215805
LOC645513 uncharacterized LOC645513 0.215805
EPAS1 endothelial PAS domain protein 1 0.215805
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.215606
RNF17 ring finger protein 17 0.215217
ZNF202 zinc finger protein 202 0.215217
GAP43 growth associated protein 43 0.214839
DLG2 discs, large homolog 2 (Drosophila) 0.214654
LRRTM4 leucine rich repeat transmembrane neuronal 4 0.214654
LOC284661 uncharacterized LOC284661 0.214654
LOC648987 uncharacterized LOC648987 0.214292
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.214168
NRXN3 neurexin 3 0.214097
NEGR1 neuronal growth regulator 1 0.213905
RYR2 ryanodine receptor 2 (cardiac) 0.213598
ZNF329 zinc finger protein 329 0.213598
PHACTR1 phosphatase and actin regulator 1 0.213264
FABP2 fatty acid binding protein 2, intestinal 0.213264
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.2131
ZMIZ1 zinc finger, MIZ-type containing 1 0.2131
FAM110B family with sequence similarity 110, member B 0.212779
OPCML opioid binding protein/cell adhesion molecule-like 0.212779
LOC400927 TPTE and PTEN homologous inositol lipid phosphatase pseudogene 0.212622
LINC01587 long intergenic non-protein coding RNA 1587 0.212466
PEX7 peroxisomal biogenesis factor 7 0.211427
DCLK1 doublecortin-like kinase 1 0.211285
CERS6 ceramide synthase 6 0.210869
LRRC4C leucine rich repeat containing 4C 0.209089
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.209089
AHCYL2 adenosylhomocysteinase-like 2 0.209089
DEPTOR DEP domain containing MTOR-interacting protein 0.209089
RPH3A rabphilin 3A 0.209089
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.208854
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene) 0.208174
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.207955
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.207634
KRT2 keratin 2, type II 0.207529
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 0.203625
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.202681
TMEM196 transmembrane protein 196 0.200955
BID BH3 interacting domain death agonist 0.200161
MMS22L MMS22-like, DNA repair protein 0.197161
NPSR1 neuropeptide S receptor 1 0.195546
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 0.193937
SV2C synaptic vesicle glycoprotein 2C 0.193438
CST9 cystatin 9 (testatin) 0.193438
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.193438
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 0.190753
YPEL1 yippee-like 1 (Drosophila) 0.190753
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.189575
THBS4 thrombospondin 4 0.187148
TMPO thymopoietin 0.186221
BMPR1B bone morphogenetic protein receptor, type IB 0.185634
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.184528
NFE2 nuclear factor, erythroid 2 0.1835
ITGA1 integrin, alpha 1 0.182775
VWF von Willebrand factor 0.179496
COL5A1 collagen, type V, alpha 1 0.176539
COL4A1 collagen, type IV, alpha 1 0.176539
GRHL2 grainyhead-like 2 (Drosophila) 0.176331
BMP5 bone morphogenetic protein 5 0.175324