abnormality of the pleura Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description An abnormality of the pulmonary pleura, the thin, transparent membrane which covers the lungs and lines the inside of the chest walls. (Human Phenotype Ontology, HP_0002103)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0002103
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Genes

39 genes associated with the abnormality of the pleura phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
C4A complement component 4A (Rodgers blood group)
CCBE1 collagen and calcium binding EGF domains 1
COL3A1 collagen, type III, alpha 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DICER1 dicer 1, ribonuclease type III
DNASE1L3 deoxyribonuclease I-like 3
FAT4 FAT atypical cadherin 4
FLCN folliculin
GUSB glucuronidase, beta
HFE hemochromatosis
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL10 interleukin 10
IL12RB2 interleukin 12 receptor, beta 2
IL23R interleukin 23 receptor
IL6 interleukin 6
KIF11 kinesin family member 11
LBR lamin B receptor
MEFV Mediterranean fever
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MYD88 myeloid differentiation primary response 88
NOD2 nucleotide-binding oligomerization domain containing 2
PRSS1 protease, serine, 1 (trypsin 1)
PRTN3 proteinase 3
PTCH1 patched 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SOX18 SRY (sex determining region Y)-box 18
SPINK1 serine peptidase inhibitor, Kazal type 1
STAT4 signal transducer and activator of transcription 4
TLR4 toll-like receptor 4
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TREX1 three prime repair exonuclease 1
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2