abnormality of the nose Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An abnormality of the nose. (Human Phenotype Ontology, HP_0000366)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0000366
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Genes

166 genes associated with the abnormality of the nose phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
FGFR2 fibroblast growth factor receptor 2 2.11861
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 1.85306
KITLG KIT ligand 1.45868
MSMB microseminoprotein, beta- 1.3841
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 1.37339
SMAD7 SMAD family member 7 1.35789
CDK10 cyclin-dependent kinase 10 1.34184
HYKK hydroxylysine kinase 1.30609
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.23231
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 1.21853
ITGA6 integrin, alpha 6 1.18241
IRF4 interferon regulatory factor 4 1.11616
IKZF1 IKAROS family zinc finger 1 (Ikaros) 1.09168
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 1.06805
ARID5B AT rich interactive domain 5B (MRF1-like) 1.05158
NELL1 NEL-like 1 (chicken) 1.05014
UHRF1BP1 UHRF1 binding protein 1 1.03592
HNF1B HNF1 homeobox B 1.02114
CHODL chondrolectin 1.00627
BIVM basic, immunoglobulin-like variable motif containing 1.00453
CDK1 cyclin-dependent kinase 1 1.00286
BARD1 BRCA1 associated RING domain 1 0.997689
TERT telomerase reverse transcriptase 0.977463
ALCAM activated leukocyte cell adhesion molecule 0.947546
MAP3K7CL MAP3K7 C-terminal like 0.94488
NXPH1 neurexophilin 1 0.938357
CLIC6 chloride intracellular channel 6 0.896372
FRMD4A FERM domain containing 4A 0.889988
GFPT2 glutamine-fructose-6-phosphate transaminase 2 0.887592
SNED1 sushi, nidogen and EGF-like domains 1 0.885423
PHF21A PHD finger protein 21A 0.884602
CSMD1 CUB and Sushi multiple domains 1 0.879214
CHUK conserved helix-loop-helix ubiquitous kinase 0.863079
LONP2 lon peptidase 2, peroxisomal 0.856292
BMPER BMP binding endothelial regulator 0.853672
UST uronyl-2-sulfotransferase 0.853321
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 0.851016
C4ORF22 chromosome 4 open reading frame 22 0.849327
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 0.846584
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.84498
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 0.844241
COL25A1 collagen, type XXV, alpha 1 0.843198
PRKCQ protein kinase C, theta 0.841148
RNF150 ring finger protein 150 0.840142
CNTNAP2 contactin associated protein-like 2 0.828053
TCF20 transcription factor 20 (AR1) 0.823019
ATAD3B ATPase family, AAA domain containing 3B 0.817516
PDLIM5 PDZ and LIM domain 5 0.797287
CDHR1 cadherin-related family member 1 0.792855
GLIS3 GLIS family zinc finger 3 0.789787
MYOM2 myomesin 2 0.784773
SYNE1 spectrin repeat containing, nuclear envelope 1 0.782964
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.780031
FANCE Fanconi anemia, complementation group E 0.777754
CDKN2B-AS1 CDKN2B antisense RNA 1 0.777589
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.770746
CASC15 cancer susceptibility candidate 15 (non-protein coding) 0.768696
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.759822
MUC12 mucin 12, cell surface associated 0.754763
PCDH15 protocadherin-related 15 0.74997
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 0.746311
KCNMB2 potassium channel subfamily M regulatory beta subunit 2 0.745864
MUSK muscle, skeletal, receptor tyrosine kinase 0.742364
FRYL FRY-like 0.740245
TYR tyrosinase 0.738394
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 0.73677
NTN1 netrin 1 0.735423
NPAS3 neuronal PAS domain protein 3 0.731062
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.729372
MACROD2 MACRO domain containing 2 0.725675
JAZF1 JAZF zinc finger 1 0.724077
LINC00578 long intergenic non-protein coding RNA 578 0.719439
OPCML opioid binding protein/cell adhesion molecule-like 0.717203
LOC643542 uncharacterized LOC643542 0.71538
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 0.714661
CLRN3 clarin 3 0.70642
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 0.703184
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 0.702831
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.699027
ARHGEF33 Rho guanine nucleotide exchange factor (GEF) 33 0.698689
SULF1 sulfatase 1 0.697346
CTBP2 C-terminal binding protein 2 0.696681
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.69439
OLFML2B olfactomedin-like 2B 0.693425
SORBS2 sorbin and SH3 domain containing 2 0.689656
PLXNA4 plexin A4 0.684849
RNF44 ring finger protein 44 0.682533
CTNND2 catenin (cadherin-associated protein), delta 2 0.675124
PTPRD protein tyrosine phosphatase, receptor type, D 0.672202
BAK1 BCL2-antagonist/killer 1 0.671582
SCARA5 scavenger receptor class A, member 5 0.671341
SGMS1 sphingomyelin synthase 1 0.669642
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.667695
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 0.664175
SLC35F4 solute carrier family 35, member F4 0.664175
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.654787
PREPL prolyl endopeptidase-like 0.653345
TARSL2 threonyl-tRNA synthetase-like 2 0.640797
NRXN3 neurexin 3 0.638696
LOC284294 uncharacterized LOC284294 0.629202
FAM178B family with sequence similarity 178, member B 0.629202
LRFN2 leucine rich repeat and fibronectin type III domain containing 2 0.62527
AK5 adenylate kinase 5 0.619739
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.566352
RTEL1 regulator of telomere elongation helicase 1 0.54147
PADI6 peptidyl arginine deiminase, type VI 0.535661
APOM apolipoprotein M 0.531208
ZNRD1-AS1 ZNRD1 antisense RNA 1 0.48992
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.456014
CLPTM1L CLPTM1-like 0.456014
ACOXL acyl-CoA oxidase-like 0.456014
PSCA prostate stem cell antigen 0.456014
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific 0.446865
COLCA2 colorectal cancer associated 2 0.43266
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.43266
SP140 SP140 nuclear body protein 0.43266
EMBP1 embigin pseudogene 1 0.429765
LMTK2 lemur tyrosine kinase 2 0.424122
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 0.416272
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 0.416272
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.416272
LSP1 lymphocyte-specific protein 1 0.413389
PRKD2 protein kinase D2 0.411631
RHPN2 rhophilin, Rho GTPase binding protein 2 0.410522
EHBP1 EH domain binding protein 1 0.408206
MECOM MDS1 and EVI1 complex locus 0.407127
PHLDB1 pleckstrin homology-like domain, family B, member 1 0.407127
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.407127
THADA thyroid adenoma associated 0.403699
RNF146 ring finger protein 146 0.401639
ITGA9 integrin, alpha 9 0.396989
COL1A1 collagen, type I, alpha 1 0.396183
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2 0.396183
RAD51B RAD51 paralog B 0.390094
MT1A metallothionein 1A 0.389813
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 0.386957
ZNF230 zinc finger protein 230 0.384544
MTAP methylthioadenosine phosphorylase 0.384544
TNRC6B trinucleotide repeat containing 6B 0.382682
TGM5 transglutaminase 5 0.376528
CLEC16A C-type lectin domain family 16, member A 0.376528
ACTA2 actin, alpha 2, smooth muscle, aorta 0.376528
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) 0.376528
LINC00299 long intergenic non-protein coding RNA 299 0.373428
TSSC1 tumor suppressing subtransferable candidate 1 0.371448
UCK2 uridine-cytidine kinase 2 0.370544
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.370544
RYR2 ryanodine receptor 2 (cardiac) 0.370544
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.370544
GLI3 GLI family zinc finger 3 0.370544
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.367064
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.367064
RBMS3 RNA binding motif, single stranded interacting protein 3 0.367064
HAPLN1 hyaluronan and proteoglycan link protein 1 0.367064
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.36461
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.36461
SDCCAG8 serologically defined colon cancer antigen 8 0.362754
TSLP thymic stromal lymphopoietin 0.362606
FBN1 fibrillin 1 0.360941
GRIK1 glutamate receptor, ionotropic, kainate 1 0.360941
SPATA22 spermatogenesis associated 22 0.358508
IL1RAP interleukin 1 receptor accessory protein 0.358325
PARD3 par-3 family cell polarity regulator 0.357225
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.357225
CEMIP cell migration inducing protein, hyaluronan binding 0.342683
HLA-F major histocompatibility complex, class I, F 0.341781