abnormality of the myocardium Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0001637
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Genes

221 genes associated with the abnormality of the myocardium phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.5154
SSFA2 sperm specific antigen 2 1.26196
LOC100506901 1.16177
KIAA1755 KIAA1755 1.15993
IPMK inositol polyphosphate multikinase 1.14515
CSMD1 CUB and Sushi multiple domains 1 1.14225
UTRN utrophin 1.11058
CD46 CD46 molecule, complement regulatory protein 1.09351
CCDC141 coiled-coil domain containing 141 1.09351
MAOA monoamine oxidase A 1.08962
MACROD2 MACRO domain containing 2 1.06703
FAM133A family with sequence similarity 133, member A 1.04977
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 1.03647
STK36 serine/threonine kinase 36 1.02868
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.02164
HTT-AS HTT antisense RNA (head to head) 1.01692
SYT10 synaptotagmin X 1.01636
IL12B interleukin 12B 1.01337
FBXL17 F-box and leucine-rich repeat protein 17 0.978536
DOCK9 dedicator of cytokinesis 9 0.973681
COL28A1 collagen, type XXVIII, alpha 1 0.969142
FADS1 fatty acid desaturase 1 0.964823
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.957533
NPAS3 neuronal PAS domain protein 3 0.930595
ESRRG estrogen-related receptor gamma 0.927189
UCK2 uridine-cytidine kinase 2 0.926745
LINGO2 leucine rich repeat and Ig domain containing 2 0.920356
SCML4 sex comb on midleg-like 4 (Drosophila) 0.909246
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.900093
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.874571
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.856534
KYNU kynureninase 0.840142
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.818279
CYTH1 cytohesin 1 0.793451
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.759822
MYO5B myosin VB 0.756252
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.74997
ULK4 unc-51 like kinase 4 0.742364
DMD dystrophin 0.706786
CHN1 chimerin 1 0.655516
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.595442
FGF13 fibroblast growth factor 13 0.584889
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 0.562717
TOPAZ1 testis and ovary specific PAZ domain containing 1 0.562717
EYS eyes shut homolog (Drosophila) 0.554075
OSTM1 osteopetrosis associated transmembrane protein 1 0.545725
SHC4 SHC (Src homology 2 domain containing) family, member 4 0.543523
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1 0.540309
UGT3A2 UDP glycosyltransferase 3 family, polypeptide A2 0.539082
CAMK4 calcium/calmodulin-dependent protein kinase IV 0.537098
KIF26B kinesin family member 26B 0.535185
TBC1D2B TBC1 domain family, member 2B 0.531556
NIPBL Nipped-B homolog (Drosophila) 0.525058
FBXW11 F-box and WD repeat domain containing 11 0.514254
POU2F1 POU class 2 homeobox 1 0.507122
FBXO38 F-box protein 38 0.503277
ATRNL1 attractin-like 1 0.497589
AKAP13 A kinase (PRKA) anchor protein 13 0.482503
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.478156
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.43206
CHRM2 cholinergic receptor, muscarinic 2 0.424122
NKX2-5 NK2 homeobox 5 0.417635
BAG3 BCL2-associated athanogene 3 0.413807
CEP85L centrosomal protein 85kDa-like 0.408825
ZBTB17 zinc finger and BTB domain containing 17 0.390936
FNDC3B fibronectin type III domain containing 3B 0.390936
RFX4 regulatory factor X, 4 (influences HLA class II expression) 0.386983
CPNE8 copine VIII 0.382633
COL17A1 collagen, type XVII, alpha 1 0.372031
HCG22 HLA complex group 22 0.366827
TNNT2 troponin T type 2 (cardiac) 0.366137
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.366137
RUNX1 runt-related transcription factor 1 0.358116
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.356732
FAM149B1 family with sequence similarity 149, member B1 0.356584
ADD2 adducin 2 (beta) 0.356548
PDE11A phosphodiesterase 11A 0.35372
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 0.348735
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 0.347205
FGF1 fibroblast growth factor 1 (acidic) 0.346142
CPNE5 copine V 0.345206
NTM neurotrimin 0.34437
TMEM135 transmembrane protein 135 0.343403
PADI3 peptidyl arginine deiminase, type III 0.343333
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.340926
SLC35F1 solute carrier family 35, member F1 0.3407
ACTN4 actinin, alpha 4 0.338502
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 0.338502
CNTN5 contactin 5 0.335231
GIGYF1 GRB10 interacting GYF protein 1 0.334339
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.332807
KIAA1715 KIAA1715 0.332607
NUGGC nuclear GTPase, germinal center associated 0.332291
CLCNKA chloride channel, voltage-sensitive Ka 0.331274
NRG1 neuregulin 1 0.331041
PHF11 PHD finger protein 11 0.330164
LOC100507053 uncharacterized LOC100507053 0.330164
OSBP2 oxysterol binding protein 2 0.327099
DCP1A decapping mRNA 1A 0.326976
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.326976
BCL2 B-cell CLL/lymphoma 2 0.326976
SMAD3 SMAD family member 3 0.325908
DAB2IP DAB2 interacting protein 0.324368
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.324368
TMEM132D transmembrane protein 132D 0.324368
FABP7 fatty acid binding protein 7, brain 0.323822
CA10 carbonic anhydrase X 0.323079
EFNA5 ephrin-A5 0.32286
ARRB1 arrestin, beta 1 0.32254
PRKG1 protein kinase, cGMP-dependent, type I 0.321252
MAPK1 mitogen-activated protein kinase 1 0.320975
ZNF385D zinc finger protein 385D 0.320185
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.320185
DOCK4 dedicator of cytokinesis 4 0.319291
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.318834
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.318182
CHD6 chromodomain helicase DNA binding protein 6 0.316985
CMYA5 cardiomyopathy associated 5 0.316798
KIAA1549L KIAA1549-like 0.316736
PIEZO2 piezo-type mechanosensitive ion channel component 2 0.316553
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.316023
ELAVL2 ELAV like neuron-specific RNA binding protein 2 0.315219
TP73 tumor protein p73 0.314887
WDR86 WD repeat domain 86 0.314821
LGALS4 lectin, galactoside-binding, soluble, 4 0.314691
CNPY3 canopy FGF signaling regulator 3 0.314563
LDAH lipid droplet associated hydrolase 0.313755
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.313398
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.313281
NCEH1 neutral cholesterol ester hydrolase 1 0.312059
TK1 thymidine kinase 1, soluble 0.311589
PTK2 protein tyrosine kinase 2 0.311487
MAP2 microtubule-associated protein 2 0.310891
MYH11 myosin, heavy chain 11, smooth muscle 0.310891
VWC2L von Willebrand factor C domain containing protein 2-like 0.31065
ANKRD33B ankyrin repeat domain 33B 0.310508
MBD5 methyl-CpG binding domain protein 5 0.31032
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.31032
ZFPM2 zinc finger protein, FOG family member 2 0.309464
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.308416
PARP12 poly (ADP-ribose) polymerase family, member 12 0.308216
VWA3B von Willebrand factor A domain containing 3B 0.306334
WBSCR17 Williams-Beuren syndrome chromosome region 17 0.306028
EBF1 early B-cell factor 1 0.305927
SLC38A8 solute carrier family 38, member 8 0.305795
RALYL RALY RNA binding protein-like 0.305598
TENM4 teneurin transmembrane protein 4 0.305501
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.304871
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 0.304871
MCPH1 microcephalin 1 0.304688
LAMA1 laminin, alpha 1 0.304567
KLHL21 kelch-like family member 21 0.304388
MTPN myotrophin 0.304329
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 0.303951
SEC31B SEC31 homolog B (S. cerevisiae) 0.303696
KLHL1 kelch-like family member 1 0.303473
TCF21 transcription factor 21 0.303363
ALK anaplastic lymphoma receptor tyrosine kinase 0.303363
TGFB2 transforming growth factor, beta 2 0.303199
TMEM87B transmembrane protein 87B 0.301989
ITGA1 integrin, alpha 1 0.301323
NCOA1 nuclear receptor coactivator 1 0.301059
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.300542
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 0.300374
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.300015
ITGA9 integrin, alpha 9 0.299987
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 0.299906
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 0.299879
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.299504
RAB40C RAB40C, member RAS oncogene family 0.299478
EML6 echinoderm microtubule associated protein like 6 0.29932
ACTA2 actin, alpha 2, smooth muscle, aorta 0.299035
SGCZ sarcoglycan, zeta 0.298831
ALG9 ALG9, alpha-1,2-mannosyltransferase 0.298579
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 0.298209
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.298039
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 0.297354
SSUH2 ssu-2 homolog (C. elegans) 0.296966
LAMB1 laminin, beta 1 0.296521
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.2965
FAS Fas cell surface death receptor 0.295898
TMEM232 transmembrane protein 232 0.295056
RNLS renalase, FAD-dependent amine oxidase 0.294858
ANTXR1 anthrax toxin receptor 1 0.294661
ZNF516 zinc finger protein 516 0.294391
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 0.294125
CLMN calmin (calponin-like, transmembrane) 0.293993
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.293993
CPQ carboxypeptidase Q 0.293937
NCALD neurocalcin delta 0.293919
TRIM67 tripartite motif containing 67 0.293826
OPCML opioid binding protein/cell adhesion molecule-like 0.293461
DLG2 discs, large homolog 2 (Drosophila) 0.293388
GRM5 glutamate receptor, metabotropic 5 0.293371
VAV3 vav 3 guanine nucleotide exchange factor 0.293245
ACYP2 acylphosphatase 2, muscle type 0.292737
TRPM5 transient receptor potential cation channel, subfamily M, member 5 0.29272
FAXC failed axon connections homolog (Drosophila) 0.292651
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.292497
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.292463
IDE insulin-degrading enzyme 0.288994
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.288994
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.285193
SPEG SPEG complex locus 0.283941
ADORA3 adenosine A3 receptor 0.283346
LOC100507462 uncharacterized LOC100507462 0.281038
FLJ37453 uncharacterized LOC729614 0.278898
CRYAB crystallin, alpha B 0.278535
CENPO centromere protein O 0.276903
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.276178
FAM19A2 family with sequence similarity 19 (chemokine (C-C motif)-like), member A2 0.276099
SCN10A sodium channel, voltage gated, type X alpha subunit 0.275482
NACA nascent polypeptide-associated complex alpha subunit 0.272938
PRPF3 pre-mRNA processing factor 3 0.272676
NCKIPSD NCK interacting protein with SH3 domain 0.272165
IP6K2 inositol hexakisphosphate kinase 2 0.264337
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) 0.26359
MSI1 musashi RNA-binding protein 1 0.258701
PPP4C protein phosphatase 4, catalytic subunit 0.254996
NAE1 NEDD8 activating enzyme E1 subunit 1 0.252474
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 0.250879