abnormality of the cerebral subcortex Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An abnormality of the cerebral subcortex. (Human Phenotype Ontology, HP_0010993)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0010993
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Genes

204 genes associated with the abnormality of the cerebral subcortex phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
TRIM65 tripartite motif containing 65 1.1701
TRIM47 tripartite motif containing 47 0.909907
WBP2 WW domain binding protein 2 0.595188
GMDS GDP-mannose 4,6-dehydratase 0.556236
SETBP1 SET binding protein 1 0.533847
PDCD11 programmed cell death 11 0.437027
ADAMTS9-AS2 ADAMTS9 antisense RNA 2 0.413807
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 0.413807
FBF1 Fas (TNFRSF6) binding factor 1 0.410844
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.408206
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.408206
MRPL38 mitochondrial ribosomal protein L38 0.407852
NT5C2 5'-nucleotidase, cytosolic II 0.406884
PMF1 polyamine-modulated factor 1 0.406588
UNC13D unc-13 homolog D (C. elegans) 0.406304
COL25A1 collagen, type XXV, alpha 1 0.405267
LPP LIM domain containing preferred translocation partner in lipoma 0.405267
CRBN cereblon 0.405267
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.402523
PTGDR prostaglandin D2 receptor (DP) 0.401355
ACOX1 acyl-CoA oxidase 1, palmitoyl 0.400586
KIAA1549 KIAA1549 0.400021
AMZ2P1 archaelysin family metallopeptidase 2 pseudogene 1 0.398647
CALHM1 calcium homeostasis modulator 1 0.398647
CYP4Z2P cytochrome P450, family 4, subfamily Z, polypeptide 2, pseudogene 0.39804
TRPM1 transient receptor potential cation channel, subfamily M, member 1 0.396981
PRDM16 PR domain containing 16 0.396981
SYN2 synapsin II 0.396981
PPP1R36 protein phosphatase 1, regulatory subunit 36 0.393867
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.393472
CHL1 cell adhesion molecule L1-like 0.393048
LEPROTL1 leptin receptor overlapping transcript-like 1 0.392247
FOXP2 forkhead box P2 0.391869
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.391832
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.39115
ITGA9 integrin, alpha 9 0.39051
CNTNAP2 contactin associated protein-like 2 0.389846
PITRM1 pitrilysin metallopeptidase 1 0.389846
PDZD2 PDZ domain containing 2 0.389396
LRRC4C leucine rich repeat containing 4C 0.389192
IGSF21 immunoglobin superfamily, member 21 0.38808
KIRREL3 kin of IRRE like 3 (Drosophila) 0.387478
LOC285692 uncharacterized LOC285692 0.387478
DNAH9 dynein, axonemal, heavy chain 9 0.387361
LOC100288728 uncharacterized LOC100288728 0.387131
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 0.386905
GEMIN6 gem (nuclear organelle) associated protein 6 0.386356
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.386356
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.385832
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.385085
SLC25A44 solute carrier family 25, member 44 0.385085
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.384088
ICA1L islet cell autoantigen 1,69kDa-like 0.383933
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.383715
GLRX3 glutaredoxin 3 0.383587
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.383084
NCOA2 nuclear receptor coactivator 2 0.382881
CALCRL calcitonin receptor-like 0.381863
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.381863
MYO7B myosin VIIB 0.381645
FHOD3 formin homology 2 domain containing 3 0.381086
TRIM67 tripartite motif containing 67 0.380918
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.380715
PCGF6 polycomb group ring finger 6 0.380002
RNF144B ring finger protein 144B 0.379847
MYO6 myosin VI 0.379492
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.379327
FHIT fragile histidine triad 0.378843
ERCC6 excision repair cross-complementation group 6 0.378669
COLGALT2 collagen beta(1-O)galactosyltransferase 2 0.378529
SH3PXD2A SH3 and PX domains 2A 0.378376
LRRTM4 leucine rich repeat transmembrane neuronal 4 0.378224
SRSF7 serine/arginine-rich splicing factor 7 0.378224
CARF calcium responsive transcription factor 0.378224
AK9 adenylate kinase 9 0.37749
LOC100505841 zinc finger protein 474-like 0.377306
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.377208
GALM galactose mutarotase (aldose 1-epimerase) 0.377069
WASF3 WAS protein family, member 3 0.376931
RHBDD1 rhomboid domain containing 1 0.376661
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.376528
LRFN2 leucine rich repeat and fibronectin type III domain containing 2 0.376266
PMEL premelanosome protein 0.376139
LOC100128714 uncharacterized LOC100128714 0.375284
LIMS2 LIM and senescent cell antigen-like domains 2 0.374483
IL21R interleukin 21 receptor 0.373523
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 0.372162
DOK6 docking protein 6 0.370523
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.370523
CARS cysteinyl-tRNA synthetase 0.369891
STX8 syntaxin 8 0.369737
LOC646730 uncharacterized LOC646730 0.369586
KDM4C lysine (K)-specific demethylase 4C 0.369287
CDH13 cadherin 13 0.368093
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 0.367377
UNQ6494 uncharacterized LOC100129066 0.36682
TEX41 testis expressed 41 (non-protein coding) 0.36676
SLC35F3 solute carrier family 35, member F3 0.366521
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.366521
CCDC7 coiled-coil domain containing 7 0.366172
CD226 CD226 molecule 0.366115
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 0.365501
TPCN1 two pore segment channel 1 0.365447
NAP1L4 nucleosome assembly protein 1-like 4 0.365447
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.365074
FRMD4A FERM domain containing 4A 0.364359
GPC5 glypican 5 0.363601
AGBL1 ATP/GTP binding protein-like 1 0.363601
LIMCH1 LIM and calponin homology domains 1 0.36345
FAM19A2 family with sequence similarity 19 (chemokine (C-C motif)-like), member A2 0.362959
ACADSB acyl-CoA dehydrogenase, short/branched chain 0.362815
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.362485
FGD4 FYVE, RhoGEF and PH domain containing 4 0.362485
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.362028
SOBP sine oculis binding protein homolog (Drosophila) 0.361805
FCHSD2 FCH and double SH3 domains 2 0.361456
ESRRG estrogen-related receptor gamma 0.361157
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 0.361115
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 0.360866
TET3 tet methylcytosine dioxygenase 3 0.360702
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.359535
CCDC125 coiled-coil domain containing 125 0.359313
PRKG1 protein kinase, cGMP-dependent, type I 0.359276
SERINC5 serine incorporator 5 0.358056
CDK14 cyclin-dependent kinase 14 0.358023
RAB20 RAB20, member RAS oncogene family 0.357923
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.35763
BIN1 bridging integrator 1 0.357352
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.357043
NEB nebulin 0.356806
MFSD12 major facilitator superfamily domain containing 12 0.356706
LRP1B low density lipoprotein receptor-related protein 1B 0.356573
LGALS9 lectin, galactoside-binding, soluble, 9 0.356573
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 0.356508
RIF1 replication timing regulatory factor 1 0.35596
ZNF264 zinc finger protein 264 0.35596
NPAS3 neuronal PAS domain protein 3 0.355929
LSP1 lymphocyte-specific protein 1 0.355679
CDK2 cyclin-dependent kinase 2 0.355311
SOX5 SRY (sex determining region Y)-box 5 0.355281
TSEN15 TSEN15 tRNA splicing endonuclease subunit 0.355191
MACROD2 MACRO domain containing 2 0.354924
ANKRD33B ankyrin repeat domain 33B 0.354924
RORA RAR-related orphan receptor A 0.354895
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.354691
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.354404
COBL cordon-bleu WH2 repeat protein 0.35432
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.354263
MGST2 microsomal glutathione S-transferase 2 0.354179
TCERG1L transcription elongation regulator 1-like 0.354179
RNF165 ring finger protein 165 0.353498
XKR4 XK, Kell blood group complex subunit-related family, member 4 0.353418
MEIS2 Meis homeobox 2 0.352924
DOCK1 dedicator of cytokinesis 1 0.352496
TGFBR3 transforming growth factor, beta receptor III 0.352496
ZFYVE28 zinc finger, FYVE domain containing 28 0.352299
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.352104
ADCY2 adenylate cyclase 2 (brain) 0.35208
SHISA6 shisa family member 6 0.35196
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.351583
TENM4 teneurin transmembrane protein 4 0.35156
OR1D2 olfactory receptor, family 1, subfamily D, member 2 0.351329
CTBP2 C-terminal binding protein 2 0.35117
CORIN corin, serine peptidase 0.350835
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 0.350725
ACSL1 acyl-CoA synthetase long-chain family member 1 0.350151
RMDN2 regulator of microtubule dynamics 2 0.349741
DMGDH dimethylglycine dehydrogenase 0.349674
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 0.349674
FLJ40288 uncharacterized FLJ40288 0.349276
CCDC60 coiled-coil domain containing 60 0.348469
SYN3 synapsin III 0.347841
ZC3H6 zinc finger CCCH-type containing 6 0.347781
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 0.347604
DACH1 dachshund family transcription factor 1 0.347546
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1 0.34741
TTLL9 tubulin tyrosine ligase-like family member 9 0.347199
SPAG16 sperm associated antigen 16 0.347161
SDK1 sidekick cell adhesion molecule 1 0.347066
RAB5B RAB5B, member RAS oncogene family 0.347047
KLB klotho beta 0.34673
CCDC102B coiled-coil domain containing 102B 0.346546
ZNF804A zinc finger protein 804A 0.346455
TMEM181 transmembrane protein 181 0.346455
SH3BP1 SH3-domain binding protein 1 0.346455
MSRA methionine sulfoxide reductase A 0.346437
DAP death-associated protein 0.346328
DNAH5 dynein, axonemal, heavy chain 5 0.346203
PTPRM protein tyrosine phosphatase, receptor type, M 0.346185
DTNB dystrobrevin, beta 0.346131
SENP7 SUMO1/sentrin specific peptidase 7 0.346025
GLB1 galactosidase, beta 1 0.345815
ACSM5 acyl-CoA synthetase medium-chain family member 5 0.345676
CCDC40 coiled-coil domain containing 40 0.345659
PTCH1 patched 1 0.345436
FBXO10 F-box protein 10 0.345251
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.345251
FTSJ3 FtsJ homolog 3 (E. coli) 0.345251
SGPP2 sphingosine-1-phosphate phosphatase 2 0.345184
FBXO5 F-box protein 5 0.345067
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 0.344739
PDE11A phosphodiesterase 11A 0.344626
EFCAB11 EF-hand calcium binding domain 11 0.344545
NFIB nuclear factor I/B 0.34437