abnormality of nitrogen compound homeostasis Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description The presence of an abnormal concentration of nitrogen compounds. (Human Phenotype Ontology, HP_0004364)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0004364
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Genes

127 genes associated with the abnormality of nitrogen compound homeostasis phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 2.33029
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.32933
GGT1 gamma-glutamyltransferase 1 1.93961
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.7474
LUC7L LUC7-like (S. cerevisiae) 1.5063
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12 1.45868
NRXN2 neurexin 2 1.45197
CCND3 cyclin D3 1.38872
TMPRSS6 transmembrane protease, serine 6 1.25943
G6PD glucose-6-phosphate dehydrogenase 1.13619
SH2B3 SH2B adaptor protein 3 1.06041
HFE hemochromatosis 0.857956
ALMS1P Alstrom syndrome 1 pseudogene 0.844241
GCKR glucokinase (hexokinase 4) regulator 0.773372
LIPC lipase, hepatic 0.76493
RCL1 RNA terminal phosphate cyclase-like 1 0.729203
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.722646
ALPL alkaline phosphatase, liver/bone/kidney 0.600154
PNPLA3 patatin-like phospholipase domain containing 3 0.551842
GP1BA glycoprotein Ib (platelet), alpha polypeptide 0.551583
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.536585
AGBL4 ATP/GTP binding protein-like 4 0.531247
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 0.504644
RELN reelin 0.498055
ASIC2 acid sensing (proton gated) ion channel 2 0.492501
CNTLN centlein, centrosomal protein 0.488289
THPO thrombopoietin 0.486444
CEP89 centrosomal protein 89kDa 0.486444
TLL1 tolloid-like 1 0.464007
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.460997
SLC14A2 solute carrier family 14 (urea transporter), member 2 0.456014
TBX2 T-box 2 0.446865
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 0.446865
THRB thyroid hormone receptor, beta 0.443306
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 0.43266
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.429108
DOCK7 dedicator of cytokinesis 7 0.416416
HBA1 hemoglobin, alpha 1 0.413803
DENND4A DENN/MADD domain containing 4A 0.413678
TMEM79 transmembrane protein 79 0.413389
BRAP BRCA1 associated protein 0.410522
SHROOM3 shroom family member 3 0.409618
SAMM50 SAMM50 sorting and assembly machinery component 0.408757
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.407127
WDR72 WD repeat domain 72 0.404407
CDK6 cyclin-dependent kinase 6 0.403699
RPL13A ribosomal protein L13a 0.402177
XPO7 exportin 7 0.401639
TERT telomerase reverse transcriptase 0.401639
RPS11 ribosomal protein S11 0.401639
LRP2 low density lipoprotein receptor-related protein 2 0.400453
PRKCE protein kinase C, epsilon 0.400353
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.400092
TYMP thymidine phosphorylase 0.400092
MAML2 mastermind-like 2 (Drosophila) 0.399496
CCDC162P coiled-coil domain containing 162, pseudogene 0.399092
TFR2 transferrin receptor 2 0.391695
CETP cholesteryl ester transfer protein, plasma 0.39143
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.386957
MMP26 matrix metallopeptidase 26 0.38285
HSDL2 hydroxysteroid dehydrogenase like 2 0.382749
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.382512
GALP galanin-like peptide 0.378176
FGFR2 fibroblast growth factor receptor 2 0.377459
NCAPH2 non-SMC condensin II complex, subunit H2 0.376528
MMP25 matrix metallopeptidase 25 0.374251
EPO erythropoietin 0.374251
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.373016
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 0.367655
KIAA1958 KIAA1958 0.367179
SPATS2L spermatogenesis associated, serine-rich 2-like 0.364421
PRR5L proline rich 5 like 0.358314
SMYD3 SET and MYND domain containing 3 0.35717
ITFG3 integrin alpha FG-GAP repeat containing 3 0.357093
TENM4 teneurin transmembrane protein 4 0.356583
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 0.355233
NTNG2 netrin G2 0.353734
WDR20 WD repeat domain 20 0.351537
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.349184
MXRA7 matrix-remodelling associated 7 0.348317
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.348028
GRM4 glutamate receptor, metabotropic 4 0.348028
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.347654
GRIK2 glutamate receptor, ionotropic, kainate 2 0.346161
SMYD2 SET and MYND domain containing 2 0.345657
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.34392
APOC1 apolipoprotein C-I 0.34181
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.341218
CNTN1 contactin 1 0.341081
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.340919
ILDR1 immunoglobulin-like domain containing receptor 1 0.340681
COL11A2 collagen, type XI, alpha 2 0.340629
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.339971
MSRA methionine sulfoxide reductase A 0.3398
MRPL48 mitochondrial ribosomal protein L48 0.338564
PHACTR1 phosphatase and actin regulator 1 0.338243
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.338014
SYT1 synaptotagmin I 0.337708
NTM neurotrimin 0.337509
BEND5 BEN domain containing 5 0.337509
STK3 serine/threonine kinase 3 0.336403
RXRB retinoid X receptor, beta 0.33556
FOXO3 forkhead box O3 0.33525
ELAVL4 ELAV like neuron-specific RNA binding protein 4 0.334204
ESRRG estrogen-related receptor gamma 0.334138
FRMD4A FERM domain containing 4A 0.334072
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.333876
CA10 carbonic anhydrase X 0.332971
KIAA1549L KIAA1549-like 0.332956
UBE2J1 ubiquitin-conjugating enzyme E2, J1 0.332792
IL21R interleukin 21 receptor 0.332571
GOLGA1 golgin A1 0.332527
GRID2 glutamate receptor, ionotropic, delta 2 0.33234
IPO11 importin 11 0.332312
SAR1A secretion associated, Ras related GTPase 1A 0.331932
SH3GL2 SH3-domain GRB2-like 2 0.331932
TNRC6B trinucleotide repeat containing 6B 0.331877
PCDH9 protocadherin 9 0.331849
FAM217A family with sequence similarity 217, member A 0.331645
OPCML opioid binding protein/cell adhesion molecule-like 0.331272
TPM4 tropomyosin 4 0.331259
ISG20 interferon stimulated exonuclease gene 20kDa 0.33109
ZAN zonadhesin (gene/pseudogene) 0.329896
MYB v-myb avian myeloblastosis viral oncogene homolog 0.307318
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 0.306058
TFRC transferrin receptor 0.301606
SPTA1 spectrin, alpha, erythrocytic 1 0.299528