abnormality of macrophages Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An abnormality of macrophages. (Human Phenotype Ontology, HP_0004311)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0004311
Similar Terms
Downloads & Tools

Genes

216 genes associated with the abnormality of macrophages phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
LACC1 laccase (multicopper oxidoreductase) domain containing 1 1.73959
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.59554
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.41524
CCDC122 coiled-coil domain containing 122 1.22038
HLA-B major histocompatibility complex, class I, B 1.1305
LOC100130357 uncharacterized LOC100130357 1.04682
TBC1D7 TBC1 domain family, member 7 0.999507
PACRG PARK2 co-regulated 0.935608
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.882984
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 0.876775
ADAM12 ADAM metallopeptidase domain 12 0.833415
PSORS1C1 psoriasis susceptibility 1 candidate 1 0.826407
ANGPT4 angiopoietin 4 0.806402
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 0.797124
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.7965
PTPRM protein tyrosine phosphatase, receptor type, M 0.784773
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 0.776085
LPAR1 lysophosphatidic acid receptor 1 0.764079
TNS3 tensin 3 0.751857
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.737224
HAND2-AS1 HAND2 antisense RNA 1 (head to head) 0.715742
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 0.705692
PRKCE protein kinase C, epsilon 0.703184
CRX cone-rod homeobox 0.698351
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.695693
KIAA1671 KIAA1671 0.690896
ANK2 ankyrin 2, neuronal 0.684849
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.683107
IL10 interleukin 10 0.676552
RIPK2 receptor-interacting serine-threonine kinase 2 0.572823
FILIP1 filamin A interacting protein 1 0.543384
C6ORF15 chromosome 6 open reading frame 15 0.53716
ANXA11 annexin A11 0.528896
CCHCR1 coiled-coil alpha-helical rod protein 1 0.461244
HLA-DRA major histocompatibility complex, class II, DR alpha 0.449521
MICA MHC class I polypeptide-related sequence A 0.432944
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.426125
C6ORF10 chromosome 6 open reading frame 10 0.409262
MOG myelin oligodendrocyte glycoprotein 0.406706
BTNL2 butyrophilin-like 2 0.405929
ERAP1 endoplasmic reticulum aminopeptidase 1 0.404013
VARS2 valyl-tRNA synthetase 2, mitochondrial 0.404003
ZNRD1-AS1 ZNRD1 antisense RNA 1 0.396888
HCP5 HLA complex P5 (non-protein coding) 0.396722
KLRC4 killer cell lectin-like receptor subfamily C, member 4 0.390936
STAT4 signal transducer and activator of transcription 4 0.390936
ASTN2 astrotactin 2 0.383473
PSORS1C2 psoriasis susceptibility 1 candidate 2 0.383239
TFCP2L1 transcription factor CP2-like 1 0.381141
CSMD1 CUB and Sushi multiple domains 1 0.375154
HLA-F-AS1 HLA-F antisense RNA 1 0.375125
MICB MHC class I polypeptide-related sequence B 0.36852
HLA-C major histocompatibility complex, class I, C 0.358764
DDR1 discoidin domain receptor tyrosine kinase 1 0.357994
DPCR1 diffuse panbronchiolitis critical region 1 0.356404
HLA-DOB major histocompatibility complex, class II, DO beta 0.355691
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.352882
ISPD isoprenoid synthase domain containing 0.351596
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.348136
PLAC9 placenta-specific 9 0.343473
LTA lymphotoxin alpha 0.340004
HCG18 HLA complex group 18 (non-protein coding) 0.339362
MATN4 matrilin 4 0.33872
RNF175 ring finger protein 175 0.336902
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.336726
ALS2CL ALS2 C-terminal like 0.336486
TRIM26 tripartite motif containing 26 0.336252
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 0.336121
SEPHS1 selenophosphate synthetase 1 0.33425
GRIK4 glutamate receptor, ionotropic, kainate 4 0.33222
AHCY adenosylhomocysteinase 0.33178
FOXP1 forkhead box P1 0.331062
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.330937
CLASP2 cytoplasmic linker associated protein 2 0.330834
DHDDS dehydrodolichyl diphosphate synthase 0.33026
MCPH1 microcephalin 1 0.33007
SH3GL2 SH3-domain GRB2-like 2 0.32992
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 0.329105
ATP6V1G2-DDX39B ATP6V1G2-DDX39B readthrough (NMD candidate) 0.328481
CCDC180 coiled-coil domain containing 180 0.328093
GPA33 glycoprotein A33 (transmembrane) 0.327838
C9ORF171 chromosome 9 open reading frame 171 0.327264
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 0.326976
UPP2 uridine phosphorylase 2 0.326829
CNTN4 contactin 4 0.326816
HLA-F major histocompatibility complex, class I, F 0.326275
SFTA2 surfactant associated 2 0.326176
PTAR1 protein prenyltransferase alpha subunit repeat containing 1 0.32609
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) 0.326065
KDM4C lysine (K)-specific demethylase 4C 0.325035
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae) 0.324877
IL23R interleukin 23 receptor 0.324607
GNG2 guanine nucleotide binding protein (G protein), gamma 2 0.32254
GPM6A glycoprotein M6A 0.322127
POU5F1 POU class 5 homeobox 1 0.321729
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.321345
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.321159
HCG27 HLA complex group 27 (non-protein coding) 0.319608
FBXL2 F-box and leucine-rich repeat protein 2 0.318909
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.318685
MUC22 mucin 22 0.318323
RPTOR regulatory associated protein of MTOR, complex 1 0.318042
DOCK4 dedicator of cytokinesis 4 0.316985
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 0.316433
AGBL1 ATP/GTP binding protein-like 1 0.316374
WWC1 WW and C2 domain containing 1 0.315739
UBP1 upstream binding protein 1 (LBP-1a) 0.314691
PHACTR2 phosphatase and actin regulator 2 0.314691
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.314627
GPR75-ASB3 GPR75-ASB3 readthrough 0.314563
SCHIP1 schwannomin interacting protein 1 0.314499
SHANK1 SH3 and multiple ankyrin repeat domains 1 0.31406
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 0.313876
DCC DCC netrin 1 receptor 0.313108
DISP2 dispatched homolog 2 (Drosophila) 0.31305
ZC3H13 zinc finger CCCH-type containing 13 0.312219
CDK19 cyclin-dependent kinase 19 0.312165
WDFY4 WDFY family member 4 0.311286
TMEM35 transmembrane protein 35 0.310988
LOC647323 uncharacterized LOC647323 0.310135
UROC1 urocanate hydratase 1 0.309908
LDB2 LIM domain binding 2 0.30912
CNOT2 CCR4-NOT transcription complex, subunit 2 0.309035
EFCAB11 EF-hand calcium binding domain 11 0.307787
AVEN apoptosis, caspase activation inhibitor 0.307672
PPP1R10 protein phosphatase 1, regulatory subunit 10 0.307483
MDC1 mediator of DNA-damage checkpoint 1 0.307445
KIF26B kinesin family member 26B 0.306896
JARID2 jumonji, AT rich interactive domain 2 0.306299
ASIC2 acid sensing (proton gated) ion channel 2 0.306197
PCDH7 protocadherin 7 0.306095
TBC1D22A TBC1 domain family, member 22A 0.306061
LUZP2 leucine zipper protein 2 0.305309
ERLEC1 endoplasmic reticulum lectin 1 0.304995
RYR2 ryanodine receptor 2 (cardiac) 0.304933
IL1R2 interleukin 1 receptor, type II 0.30484
PDZRN4 PDZ domain containing ring finger 4 0.304749
SDK2 sidekick cell adhesion molecule 2 0.304718
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 0.30427
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 0.304211
WWTR1 WW domain containing transcription regulator 1 0.304037
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 0.303667
KTN1 kinectin 1 (kinesin receptor) 0.303445
POU6F2 POU class 6 homeobox 2 0.303011
PCSK6 proprotein convertase subtilisin/kexin type 6 0.302852
LOC339298 uncharacterized LOC339298 0.302082
NUTM1 NUT midline carcinoma, family member 1 0.301958
CCDC42 coiled-coil domain containing 42 0.301713
NOD2 nucleotide-binding oligomerization domain containing 2 0.301562
ASB3 ankyrin repeat and SOCS box containing 3 0.301532
CDCP1 CUB domain containing protein 1 0.301442
PENK proenkephalin 0.301088
FAM169B family with sequence similarity 169, member B 0.300943
LPP LIM domain containing preferred translocation partner in lipoma 0.300542
PRNT prion protein (testis specific) 0.299061
IKZF5 IKAROS family zinc finger 5 (Pegasus) 0.298554
LOC100287329 uncharacterized LOC100287329 0.298529
DAAM1 dishevelled associated activator of morphogenesis 1 0.298331
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.297681
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 0.296676
ACSBG1 acyl-CoA synthetase bubblegum family member 1 0.29626
FXYD5 FXYD domain containing ion transport regulator 5 0.296174
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.296046
FYCO1 FYVE and coiled-coil domain containing 1 0.29542
ILDR1 immunoglobulin-like domain containing receptor 1 0.294996
KANK1 KN motif and ankyrin repeat domains 1 0.294623
CDHR3 cadherin-related family member 3 0.294603
ZBTB7C zinc finger and BTB domain containing 7C 0.294506
NPHP4 nephronophthisis 4 0.294468
AGTR1 angiotensin II receptor, type 1 0.293845
CDSN corneodesmosin 0.293551
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 0.293515
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L 0.293443
PDZD2 PDZ domain containing 2 0.292737
ARMC9 armadillo repeat containing 9 0.29248
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.292412
TMPRSS4 transmembrane protease, serine 4 0.292244
MYO1D myosin ID 0.292144
TCF19 transcription factor 19 0.292094
FRMD4A FERM domain containing 4A 0.291832
CPVL carboxypeptidase, vitellogenic-like 0.291815
STIM1 stromal interaction molecule 1 0.291178
L3HYPDH L-3-hydroxyproline dehydratase (trans-) 0.290868
GLIS3 GLIS family zinc finger 3 0.289975
SGK223 homolog of rat pragma of Rnd2 0.287444
LINGO2 leucine rich repeat and Ig domain containing 2 0.286676
NNT nicotinamide nucleotide transhydrogenase 0.285852
CALN1 calneuron 1 0.280833
STK32B serine/threonine kinase 32B 0.277916
ZNF385D zinc finger protein 385D 0.276099
BSN bassoon presynaptic cytomatrix protein 0.275181
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 0.274593
ZNF451 zinc finger protein 451 0.274235
WWOX WW domain containing oxidoreductase 0.270887
MACROD2 MACRO domain containing 2 0.270538
BEST3 bestrophin 3 0.269101
MORN5 MORN repeat containing 5 0.267984
STMN2 stathmin 2 0.265615
TP73 tumor protein p73 0.264528
ZPBP zona pellucida binding protein 0.264242
MTCH1 mitochondrial carrier 1 0.264195
LOC401324 uncharacterized LOC401324 0.263407
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.26226
UBAC2 UBA domain containing 2 0.261544
FNDC1 fibronectin type III domain containing 1 0.26138
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.260774
LDLRAD3 low density lipoprotein receptor class A domain containing 3 0.260303
TMEM44 transmembrane protein 44 0.259098
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 0.258989
APCDD1L adenomatosis polyposis coli down-regulated 1-like 0.257286
NTN1 netrin 1 0.256761
MSRA methionine sulfoxide reductase A 0.255265
PRR5L proline rich 5 like 0.254586
RSPO4 R-spondin 4 0.254385
UBASH3B ubiquitin associated and SH3 domain containing B 0.252975
MS4A10 membrane-spanning 4-domains, subfamily A, member 10 0.25036