abnormality of immune serum protein physiology Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An abnormality of the concentration or function of circulating immune proteins. (Human Phenotype Ontology, HP_0011111)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0011111
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Genes

710 genes associated with the abnormality of immune serum protein physiology phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
ELOVL2 ELOVL fatty acid elongase 2 2.48085
TMEM229B transmembrane protein 229B 2.19307
SYNE2 spectrin repeat containing, nuclear envelope 2 2.16358
SLC16A9 solute carrier family 16, member 9 1.95163
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 1.88591
PKD2L1 polycystic kidney disease 2-like 1 1.85046
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.69375
PROCR protein C receptor, endothelial 1.29386
ELL2 elongation factor, RNA polymerase II, 2 1.24751
GCKR glucokinase (hexokinase 4) regulator 1.17192
RPS11 ribosomal protein S11 1.16661
SV2B synaptic vesicle glycoprotein 2B 1.14102
FADS1 fatty acid desaturase 1 1.12474
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 1.11203
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 1.09995
FADS3 fatty acid desaturase 3 1.09627
BTNL2 butyrophilin-like 2 1.08774
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 1.06504
FAM171B family with sequence similarity 171, member B 1.05518
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.05218
COL19A1 collagen, type XIX, alpha 1 1.05195
CHD2 chromodomain helicase DNA binding protein 2 1.04543
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 1.04365
FEN1 flap structure-specific endonuclease 1 1.03013
BNC2 basonuclin 2 1.02964
SAMM50 SAMM50 sorting and assembly machinery component 1.02729
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 1.02374
CRTAC1 cartilage acidic protein 1 1.02002
USP15 ubiquitin specific peptidase 15 1.01962
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.01027
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 1.00627
SORCS2 sortilin-related VPS10 domain containing receptor 2 1.00592
WTAP Wilms tumor 1 associated protein 1.00187
NPY1R neuropeptide Y receptor Y1 1.00123
PCDH9 protocadherin 9 0.998051
TMEM132D transmembrane protein 132D 0.998051
MGC27382 uncharacterized MGC27382 0.995235
FGD4 FYVE, RhoGEF and PH domain containing 4 0.990592
SGCZ sarcoglycan, zeta 0.984794
CALCB calcitonin-related polypeptide beta 0.984214
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 0.983071
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.973975
RIMS2 regulating synaptic membrane exocytosis 2 0.972518
KIF6 kinesin family member 6 0.971092
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.968595
TRIM44 tripartite motif containing 44 0.96305
PRR34 proline rich 34 0.959521
TACC2 transforming, acidic coiled-coil containing protein 2 0.956697
PCSK5 proprotein convertase subtilisin/kexin type 5 0.955595
EMC8 ER membrane protein complex subunit 8 0.944642
FGF12 fibroblast growth factor 12 0.940153
COQ6 coenzyme Q6 monooxygenase 0.929216
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.929216
GPC5 glypican 5 0.927859
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.927411
FADS2 fatty acid desaturase 2 0.924345
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.923916
ANGPTL2 angiopoietin-like 2 0.922431
LRRC16B leucine rich repeat containing 16B 0.918532
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 0.917338
C5ORF30 chromosome 5 open reading frame 30 0.912522
BCO1 beta-carotene oxygenase 1 0.910664
MYRF myelin regulatory factor 0.905894
THSD4 thrombospondin, type I, domain containing 4 0.905315
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.902293
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.899192
SAMD12 sterile alpha motif domain containing 12 0.898656
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 0.895681
SPTA1 spectrin, alpha, erythrocytic 1 0.894825
LIPC lipase, hepatic 0.893474
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 0.893306
ASIC2 acid sensing (proton gated) ion channel 2 0.891813
TSHZ2 teashirt zinc finger homeobox 2 0.89067
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.889815
PKP4 plakophilin 4 0.888782
EMC1 ER membrane protein complex subunit 1 0.885753
TCP1 t-complex 1 0.885588
ANKRD30A ankyrin repeat domain 30A 0.884439
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 0.884276
CYBRD1 cytochrome b reductase 1 0.883789
ANO4 anoctamin 4 0.881868
TENM4 teneurin transmembrane protein 4 0.877539
THSD7B thrombospondin, type I, domain containing 7B 0.87156
TMEM246 transmembrane protein 246 0.870998
PDZD2 PDZ domain containing 2 0.869471
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.869059
FRMD6 FERM domain containing 6 0.868241
ELMO1 engulfment and cell motility 1 0.868241
BTBD11 BTB (POZ) domain containing 11 0.864783
TMEM108 transmembrane protein 108 0.862558
FZD3 frizzled class receptor 3 0.862428
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.861012
CUL3 cullin 3 0.859118
SCAP SREBF chaperone 0.858001
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) 0.857878
IFI44L interferon-induced protein 44-like 0.856292
FTO fat mass and obesity associated 0.855809
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.855091
KAZN kazrin, periplakin interacting protein 0.849215
RPL7 ribosomal protein L7 0.847889
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.847561
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 0.847125
JMJD1C jumonji domain containing 1C 0.84498
GRM4 glutamate receptor, metabotropic 4 0.844241
PELI2 pellino E3 ubiquitin protein ligase family member 2 0.842167
ZNF571 zinc finger protein 571 0.840142
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 0.838165
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.837193
UNC5C unc-5 homolog C (C. elegans) 0.834343
CELF3 CUGBP, Elav-like family member 3 0.834343
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) 0.833415
PRKCE protein kinase C, epsilon 0.831588
ANKRD44 ankyrin repeat domain 44 0.831588
CRYAB crystallin, alpha B 0.83069
ALG9 ALG9, alpha-1,2-mannosyltransferase 0.83069
CADM2 cell adhesion molecule 2 0.83069
CENPP centromere protein P 0.83069
TMCO1 transmembrane and coiled-coil domains 1 0.828922
GRIK1 glutamate receptor, ionotropic, kainate 1 0.828922
ASTN2 astrotactin 2 0.82634
WAPAL wings apart-like homolog (Drosophila) 0.82634
CPNE2 copine II 0.825497
MAML3 mastermind-like 3 (Drosophila) 0.824663
SPRED2 sprouty-related, EVH1 domain containing 2 0.823837
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 0.823019
SUGCT succinyl-CoA:glutarate-CoA transferase 0.82221
ZFHX3 zinc finger homeobox 3 0.821408
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.820614
PRKG1 protein kinase, cGMP-dependent, type I 0.81905
GLIS3 GLIS family zinc finger 3 0.81601
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.81601
RSPO2 R-spondin 2 0.815267
LRP2 low density lipoprotein receptor-related protein 2 0.814503
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.814503
RYR2 ryanodine receptor 2 (cardiac) 0.813733
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 0.813733
PTPRD protein tyrosine phosphatase, receptor type, D 0.813733
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.812214
GRM7 glutamate receptor, metabotropic 7 0.812214
LOC100506272 uncharacterized LOC100506272 0.811465
PADI3 peptidyl arginine deiminase, type III 0.810722
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.809986
ATF3 activating transcription factor 3 0.807817
CCSER1 coiled-coil serine-rich protein 1 0.806402
CNGB3 cyclic nucleotide gated channel beta 3 0.80501
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.80501
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 0.803642
CALN1 calneuron 1 0.802296
OSBPL1A oxysterol binding protein-like 1A 0.801631
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.801631
CES5A carboxylesterase 5A 0.800972
TBC1D4 TBC1 domain family, member 4 0.800318
SLCO1C1 solute carrier organic anion transporter family, member 1C1 0.800318
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) 0.800318
DEPTOR DEP domain containing MTOR-interacting protein 0.799669
MTMR12 myotubularin related protein 12 0.794657
PTPRJ protein tyrosine phosphatase, receptor type, J 0.794657
ABLIM3 actin binding LIM protein family, member 3 0.793451
SBF2 SET binding factor 2 0.791675
C8ORF74 chromosome 8 open reading frame 74 0.789787
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.789787
DFNB31 deafness, autosomal recessive 31 0.789144
WDR25 WD repeat domain 25 0.788506
SSTR2 somatostatin receptor 2 0.787873
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 0.78662
ERBB4 erb-b2 receptor tyrosine kinase 4 0.786
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.785384
ENTPD3-AS1 ENTPD3 antisense RNA 1 0.785384
ANK2 ankyrin 2, neuronal 0.784165
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.784165
FLT1 fms-related tyrosine kinase 1 0.782964
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.782964
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.782369
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.781779
GUCY2EP guanylate cyclase 2E, pseudogene 0.781779
SLC38A6 solute carrier family 38, member 6 0.781192
IL23R interleukin 23 receptor 0.78061
ZNF33A zinc finger protein 33A 0.780031
UBOX5 U-box domain containing 5 0.777754
MAST4 microtubule associated serine/threonine kinase family member 4 0.777194
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.776638
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.776638
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 0.776085
MME membrane metallo-endopeptidase 0.776085
MACROD2 MACRO domain containing 2 0.77499
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.77499
PARK2 parkin RBR E3 ubiquitin protein ligase 0.77499
ADD2 adducin 2 (beta) 0.773909
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.773374
LRRC72 leucine rich repeat containing 72 0.772313
PTPRT protein tyrosine phosphatase, receptor type, T 0.771787
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 0.770746
TENM2 teneurin transmembrane protein 2 0.767696
RAD50 RAD50 homolog (S. cerevisiae) 0.766703
PLXNA4 plexin A4 0.765722
SUSD1 sushi domain containing 1 0.765722
MYH11 myosin, heavy chain 11, smooth muscle 0.762996
CADPS Ca++-dependent secretion activator 0.762459
NRCAM neuronal cell adhesion molecule 0.761395
CREB5 cAMP responsive element binding protein 5 0.760868
ZNF385D zinc finger protein 385D 0.760343
XPA xeroderma pigmentosum, complementation group A 0.759822
KCNMB2 potassium channel subfamily M regulatory beta subunit 2 0.759303
LINC00426 long intergenic non-protein coding RNA 426 0.758788
GAS7 growth arrest-specific 7 0.757258
VGLL4 vestigial-like family member 4 0.754273
PSAT1 phosphoserine aminotransferase 1 0.753299
PLA2G16 phospholipase A2, group XVI 0.752816
ITGB8 integrin, beta 8 0.752816
CMC1 C-x(9)-C motif containing 1 0.752816
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.752816
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 0.752335
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 0.751857
MICU2 mitochondrial calcium uptake 2 0.751857
AGBL1 ATP/GTP binding protein-like 1 0.74997
CHODL chondrolectin 0.748581
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.748581
DGKB diacylglycerol kinase, beta 90kDa 0.747666
PCDH15 protocadherin-related 15 0.747666
TPP2 tripeptidyl peptidase II 0.74676
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.74676
MSRB3 methionine sulfoxide reductase B3 0.745864
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 0.744976
NTF3 neurotrophin 3 0.744097
KLHL18 kelch-like family member 18 0.74366
PLCD3 phospholipase C, delta 3 0.74366
MRPL18 mitochondrial ribosomal protein L18 0.743226
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 0.742364
LINC00862 long intergenic non-protein coding RNA 862 0.74151
WIF1 WNT inhibitory factor 1 0.740664
FRMD4A FERM domain containing 4A 0.740664
A4GALT alpha 1,4-galactosyltransferase 0.740245
PODXL podocalyxin-like 0.739827
TPRG1 tumor protein p63 regulated 1 0.739411
DAPK1 death-associated protein kinase 1 0.738137
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 0.737679
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.73677
HLA-DRA major histocompatibility complex, class II, DR alpha 0.734535
NTN4 netrin 4 0.734094
KLF12 Kruppel-like factor 12 0.734094
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1 0.733655
SCFD2 sec1 family domain containing 2 0.733218
GCOM1 GRINL1A complex locus 1 0.732783
SMAD6 SMAD family member 6 0.731918
DNHD1 dynein heavy chain domain 1 0.731918
LOXL2 lysyl oxidase-like 2 0.731062
SCARA5 scavenger receptor class A, member 5 0.728537
ZNF827 zinc finger protein 827 0.728537
AKAP6 A kinase (PRKA) anchor protein 6 0.728123
KIF13B kinesin family member 13B 0.7273
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.7273
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 0.726484
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.726484
NUDCD1 NudC domain containing 1 0.726078
GRHL1 grainyhead-like 1 (Drosophila) 0.724872
NOL8 nucleolar protein 8 0.724872
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3 0.724077
NCOA6 nuclear receptor coactivator 6 0.724077
SDK2 sidekick cell adhesion molecule 2 0.723288
SCLT1 sodium channel and clathrin linker 1 0.722505
BMPR1B bone morphogenetic protein receptor, type IB 0.722505
ACADL acyl-CoA dehydrogenase, long chain 0.722505
ZNF385B zinc finger protein 385B 0.722116
DBNL drebrin-like 0.721729
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 0.721729
DNER delta/notch-like EGF repeat containing 0.721729
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.721344
REEP5 receptor accessory protein 5 0.72096
TMEM181 transmembrane protein 181 0.72096
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 0.72096
GNA14 guanine nucleotide binding protein (G protein), alpha 14 0.720196
MSI2 musashi RNA-binding protein 2 0.719817
SEC24D SEC24 family member D 0.719439
CLCN2 chloride channel, voltage-sensitive 2 0.719439
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1 0.719063
TBC1D22A TBC1 domain family, member 22A 0.717942
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 0.717572
ALK anaplastic lymphoma receptor tyrosine kinase 0.717572
COL27A1 collagen, type XXVII, alpha 1 0.716836
GAS2 growth arrest-specific 2 0.71647
CRHR1 corticotropin releasing hormone receptor 1 0.71647
DPYSL2 dihydropyrimidinase-like 2 0.716105
CPLX2 complexin 2 0.713592
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 0.712886
ANGPTL5 angiopoietin-like 5 0.712186
APOLD1 apolipoprotein L domain containing 1 0.712186
CSMD1 CUB and Sushi multiple domains 1 0.711491
LOC728989 phosphodiesterase 4D interacting protein pseudogene 0.711145
PRKCB protein kinase C, beta 0.710801
MTFMT mitochondrial methionyl-tRNA formyltransferase 0.710801
PTPRM protein tyrosine phosphatase, receptor type, M 0.710458
LRRC4C leucine rich repeat containing 4C 0.710458
RPL14 ribosomal protein L14 0.709765
FAM188A family with sequence similarity 188, member A 0.709388
R3HCC1L R3H domain and coiled-coil containing 1-like 0.708638
FAT4 FAT atypical cadherin 4 0.707893
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 0.707893
XDH xanthine dehydrogenase 0.707893
CPE carboxypeptidase E 0.707154
CDK14 cyclin-dependent kinase 14 0.706055
KIRREL3 kin of IRRE like 3 (Drosophila) 0.704609
LRRC48 leucine rich repeat containing 48 0.703894
P3H2 prolyl 3-hydroxylase 2 0.703538
SLX4IP SLX4 interacting protein 0.703184
ADAM12 ADAM metallopeptidase domain 12 0.702831
SLC38A9 solute carrier family 38, member 9 0.702128
PCDH7 protocadherin 7 0.701779
FANCE Fanconi anemia, complementation group E 0.701084
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.701084
STARD13 StAR-related lipid transfer (START) domain containing 13 0.700738
SASH1 SAM and SH3 domain containing 1 0.700393
LDB2 LIM domain binding 2 0.70005
TBX4 T-box 4 0.699708
ADGRL4 adhesion G protein-coupled receptor L4 0.698689
EP300 E1A binding protein p300 0.698351
RANBP3L RAN binding protein 3-like 0.697013
PDLIM5 PDZ and LIM domain 5 0.696681
KRT23 keratin 23, type I 0.696021
FGF14 fibroblast growth factor 14 0.696021
KCNIP4 Kv channel interacting protein 4 0.695693
HTRA3 HtrA serine peptidase 3 0.695693
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 0.695039
TECTB tectorin beta 0.69439
ARSG arylsulfatase G 0.694067
AKAP12 A kinase (PRKA) anchor protein 12 0.693105
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.692469
NELL1 NEL-like 1 (chicken) 0.691208
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.690584
KANK1 KN motif and ankyrin repeat domains 1 0.689964
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.689964
COLEC12 collectin sub-family member 12 0.689656
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.688431
TMEM63A transmembrane protein 63A 0.688128
FAM78B family with sequence similarity 78, member B 0.687222
HEPH hephaestin 0.686922
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 0.684556
PHC1 polyhomeotic homolog 1 (Drosophila) 0.684556
TNS3 tensin 3 0.683974
IARS isoleucyl-tRNA synthetase 0.683974
CNTNAP2 contactin associated protein-like 2 0.682819
MTUS2 microtubule associated tumor suppressor candidate 2 0.680552
DPYD dihydropyrimidine dehydrogenase 0.680552
VSNL1 visinin-like 1 0.679979
TBATA thymus, brain and testes associated 0.679359
CCDC149 coiled-coil domain containing 149 0.679359
ARMC4 armadillo repeat containing 4 0.679051
ISM2 isthmin 2 0.679051
ANKRD6 ankyrin repeat domain 6 0.678743
CNTNAP5 contactin associated protein-like 5 0.678743
SYNJ2 synaptojanin 2 0.678743
NLRP9 NLR family, pyrin domain containing 9 0.678131
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 0.677826
ULK2 unc-51 like autophagy activating kinase 2 0.676917
OPCML opioid binding protein/cell adhesion molecule-like 0.676917
CCDC146 coiled-coil domain containing 146 0.676616
TG thyroglobulin 0.676017
TRIM42 tripartite motif containing 42 0.675718
UPP2 uridine phosphorylase 2 0.67542
ATP7B ATPase, Cu++ transporting, beta polypeptide 0.67542
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 0.674532
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 0.674238
CAPN13 calpain 13 0.673945
RGS5 regulator of G-protein signaling 5 0.67336
EXOC6 exocyst complex component 6 0.67307
NWD2 NACHT and WD repeat domain containing 2 0.672779
SNTG1 syntrophin, gamma 1 0.67249
PCSK2 proprotein convertase subtilisin/kexin type 2 0.672202
NRDE2 NRDE-2, necessary for RNA interference, domain containing 0.672202
EFNA5 ephrin-A5 0.671914
TBX20 T-box 20 0.671914
ARFGEF3 ARFGEF family member 3 0.671341
IL2RA interleukin 2 receptor, alpha 0.671341
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.671341
EYS eyes shut homolog (Drosophila) 0.670772
CNTNAP4 contactin associated protein-like 4 0.670205
KALRN kalirin, RhoGEF kinase 0.669362
ERAP1 endoplasmic reticulum aminopeptidase 1 0.669082
ECM2 extracellular matrix protein 2, female organ and adipocyte specific 0.668803
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.668247
DCC DCC netrin 1 receptor 0.668247
ZNF490 zinc finger protein 490 0.667971
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.66742
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.666872
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.666872
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 0.666327
NBAS neuroblastoma amplified sequence 0.666327
IQGAP3 IQ motif containing GTPase activating protein 3 0.666327
RAP1A RAP1A, member of RAS oncogene family 0.665784
KCNK9 potassium channel, two pore domain subfamily K, member 9 0.665514
HMBOX1 homeobox containing 1 0.665514
METTL14 methyltransferase like 14 0.663645
LRRC66 leucine rich repeat containing 66 0.663645
CDH23 cadherin-related 23 0.662854
HYI hydroxypyruvate isomerase (putative) 0.66233
EFCAB14 EF-hand calcium binding domain 14 0.662069
SLC14A2 solute carrier family 14 (urea transporter), member 2 0.661809
NRP2 neuropilin 2 0.661032
KSR2 kinase suppressor of ras 2 0.659244
SPHKAP SPHK1 interactor, AKAP domain containing 0.658738
RAB3B RAB3B, member RAS oncogene family 0.657985
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 0.657985
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.657985
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 0.657736
TRIO trio Rho guanine nucleotide exchange factor 0.657487
FBXO10 F-box protein 10 0.656743
PLXDC2 plexin domain containing 2 0.65576
CNTN4 contactin 4 0.655516
PHACTR2 phosphatase and actin regulator 2 0.655272
MORC1 MORC family CW-type zinc finger 1 0.654545
DSC3 desmocollin 3 0.654063
C8ORF34 chromosome 8 open reading frame 34 0.653106
LVRN laeverin 0.652395
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 0.652395
SETBP1 SET binding protein 1 0.651923
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.651923
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.650987
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 0.650754
CPA1 carboxypeptidase A1 (pancreatic) 0.650754
RNF175 ring finger protein 175 0.650522
LOC100129345 uncharacterized LOC100129345 0.649829
ALG8 ALG8, alpha-1,3-glucosyltransferase 0.648884
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.648376
KIAA1671 KIAA1671 0.648376
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.647618
WDR64 WD repeat domain 64 0.647618
OR52N2 olfactory receptor, family 52, subfamily N, member 2 0.647618
BEND4 BEN domain containing 4 0.647367
ZFP30 ZFP30 zinc finger protein 0.647116
WRN Werner syndrome, RecQ helicase-like 0.647116
SOX13 SRY (sex determining region Y)-box 13 0.646866
XYLT1 xylosyltransferase I 0.646616
TRHR thyrotropin-releasing hormone receptor 0.646367
LOC285692 uncharacterized LOC285692 0.646367
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 0.646367
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.646119
HCG18 HLA complex group 18 (non-protein coding) 0.645377
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 0.645377
AIG1 androgen-induced 1 0.645377
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.645377
PTCHD4 patched domain containing 4 0.644886
GLI3 GLI family zinc finger 3 0.644886
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.644641
ADCY5 adenylate cyclase 5 0.644153
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.642942
CASC1 cancer susceptibility candidate 1 0.64127
EVC Ellis van Creveld protein 0.640797
PRR5 proline rich 5 (renal) 0.640562
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 0.640562
LARS2 leucyl-tRNA synthetase 2, mitochondrial 0.640327
CDH12 cadherin 12, type 2 (N-cadherin 2) 0.640092
RAB31 RAB31, member RAS oncogene family 0.640092
SH3TC2 SH3 domain and tetratricopeptide repeats 2 0.640092
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 0.639624
SKINTL Skint-like, pseudogene 0.639391
C9ORF135 chromosome 9 open reading frame 135 0.638927
PDE8B phosphodiesterase 8B 0.638696
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.638004
CDH13 cadherin 13 0.638004
LYN LYN proto-oncogene, Src family tyrosine kinase 0.637775
PHGDH phosphoglycerate dehydrogenase 0.637775
VDAC2 voltage-dependent anion channel 2 0.637546
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.637318
RSU1 Ras suppressor protein 1 0.636635
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K 0.636409
ZMIZ1 zinc finger, MIZ-type containing 1 0.635508
PLD1 phospholipase D1, phosphatidylcholine-specific 0.635284
FOXN3 forkhead box N3 0.634838
NCK2 NCK adaptor protein 2 0.634838
TREML4 triggering receptor expressed on myeloid cells-like 4 0.634838
PCM1 pericentriolar material 1 0.634615
UBTD1 ubiquitin domain containing 1 0.634172
GRIP1 glutamate receptor interacting protein 1 0.63351
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene) 0.63329
LIPN lipase, family member N 0.63329
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.632852
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 0.631765
GPATCH4 G patch domain containing 4 0.631333
LRRC1 leucine rich repeat containing 1 0.631333
NBEAL2 neurobeachin-like 2 0.631118
ZDHHC13 zinc finger, DHHC-type containing 13 0.630049
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.630049
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 0.629413
NPSR1 neuropeptide S receptor 1 0.629413
ABAT 4-aminobutyrate aminotransferase 0.629202
MS4A10 membrane-spanning 4-domains, subfamily A, member 10 0.629202
SYNPR synaptoporin 0.628781
ACTA2 actin, alpha 2, smooth muscle, aorta 0.628571
CTIF CBP80/20-dependent translation initiation factor 0.628362
SPATA31E1 SPATA31 subfamily E, member 1 0.628153
NRG3 neuregulin 3 0.627736
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 0.627736
FOXP1 forkhead box P1 0.627528
ZNF667 zinc finger protein 667 0.627114
EFTUD1 elongation factor Tu GTP binding domain containing 1 0.627114
LEPROTL1 leptin receptor overlapping transcript-like 1 0.626701
MEOX2 mesenchyme homeobox 2 0.626701
LRRC8D leucine rich repeat containing 8 family, member D 0.625473
LYPD6 LY6/PLAUR domain containing 6 0.625067
DPY19L1 dpy-19-like 1 (C. elegans) 0.625067
NCAM2 neural cell adhesion molecule 2 0.624865
OR10G3 olfactory receptor, family 10, subfamily G, member 3 0.624663
DFNA5 deafness, autosomal dominant 5 0.62426
NTN1 netrin 1 0.624059
CLIP1 CAP-GLY domain containing linker protein 1 0.624059
COG6 component of oligomeric golgi complex 6 0.623859
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.623459
GPX3 glutathione peroxidase 3 0.62326
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 0.62326
TRIM9 tripartite motif containing 9 0.623061
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 0.622863
TMEM87B transmembrane protein 87B 0.622073
JPH3 junctophilin 3 0.621876
PID1 phosphotyrosine interaction domain containing 1 0.621485
STRA8 stimulated by retinoic acid 8 0.621485
MYO10 myosin X 0.621289
STK32B serine/threonine kinase 32B 0.621289
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.6209
CNBD1 cyclic nucleotide binding domain containing 1 0.620705
LHX8 LIM homeobox 8 0.620318
HDLBP high density lipoprotein binding protein 0.620318
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 0.620318
XKR6 XK, Kell blood group complex subunit-related family, member 6 0.619739
VTI1B vesicle transport through interaction with t-SNAREs 1B 0.619547
STXBP5L syntaxin binding protein 5-like 0.619356
INPP5K inositol polyphosphate-5-phosphatase K 0.618783
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.617835
LOC440704 uncharacterized LOC440704 0.617647
RORA RAR-related orphan receptor A 0.617647
ASB15 ankyrin repeat and SOCS box containing 15 0.617459
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 0.616892
BSPRY B-box and SPRY domain containing 0.616892
MEDAG mesenteric estrogen-dependent adipogenesis 0.616698
MCTP2 multiple C2 domains, transmembrane 2 0.616698
LOXL4 lysyl oxidase-like 4 0.616311
SYNDIG1 synapse differentiation inducing 1 0.614969
PTGFR prostaglandin F receptor (FP) 0.614589
MYO3B myosin IIIB 0.61421
PLA2R1 phospholipase A2 receptor 1, 180kDa 0.613645
ATL2 atlastin GTPase 2 0.613269
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1 0.612895
GSG1L GSG1-like 0.612709
ZFYVE28 zinc finger, FYVE domain containing 28 0.612523
SIK2 salt-inducible kinase 2 0.612337
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 0.612337
SEC13 SEC13 homolog (S. cerevisiae) 0.611966
NCALD neurocalcin delta 0.611781
EIF3H eukaryotic translation initiation factor 3, subunit H 0.611597
UNC79 unc-79 homolog (C. elegans) 0.611413
LRP1B low density lipoprotein receptor-related protein 1B 0.611045
TBC1D14 TBC1 domain family, member 14 0.610679
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 0.610133
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.609589
NIPAL1 NIPA-like domain containing 1 0.609589
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 0.609228
DOCK2 dedicator of cytokinesis 2 0.609048
SOX5 SRY (sex determining region Y)-box 5 0.608689
LCLAT1 lysocardiolipin acyltransferase 1 0.608689
CTNND2 catenin (cadherin-associated protein), delta 2 0.608689
NPC1 Niemann-Pick disease, type C1 0.608689
STX8 syntaxin 8 0.60851
MBOAT1 membrane bound O-acyltransferase domain containing 1 0.608153
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.607975
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.607975
VCL vinculin 0.607797
FRAS1 Fraser extracellular matrix complex subunit 1 0.606913
NLRP12 NLR family, pyrin domain containing 12 0.606913
FNBP1L formin binding protein 1-like 0.606737
IL4R interleukin 4 receptor 0.606562
WDR43 WD repeat domain 43 0.606562
TRIM36 tripartite motif containing 36 0.606387
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 0.606037
TIMP2 TIMP metallopeptidase inhibitor 2 0.606037
NT5DC1 5'-nucleotidase domain containing 1 0.605688
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.605688
OTUD7A OTU deubiquitinase 7A 0.605341
PRKCH protein kinase C, eta 0.605168
TMEM106B transmembrane protein 106B 0.604822
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 0.604822
HNF1B HNF1 homeobox B 0.604306
CSF1 colony stimulating factor 1 (macrophage) 0.603964
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.603282
SCHIP1 schwannomin interacting protein 1 0.602943
EBF1 early B-cell factor 1 0.602943
WDR72 WD repeat domain 72 0.602943
EPHA6 EPH receptor A6 0.602605
MYO15A myosin XVA 0.6021
METAP2 methionyl aminopeptidase 2 0.601932
C4ORF45 chromosome 4 open reading frame 45 0.601597
DAGLA diacylglycerol lipase, alpha 0.601097
ATAD2B ATPase family, AAA domain containing 2B 0.600766
CUL1 cullin 1 0.60027
CELA2B chymotrypsin-like elastase family, member 2B 0.599941
ALDOB aldolase B, fructose-bisphosphate 0.599941
BANF2 barrier to autointegration factor 2 0.599449
XKR4 XK, Kell blood group complex subunit-related family, member 4 0.599449
DNAH9 dynein, axonemal, heavy chain 9 0.599285
GPATCH2 G patch domain containing 2 0.598635
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.598473
ADGB androglobin 0.598149
IFFO1 intermediate filament family orphan 1 0.597988
HPSE2 heparanase 2 (inactive) 0.597185
GXYLT2 glucoside xylosyltransferase 2 0.597026
MET MET proto-oncogene, receptor tyrosine kinase 0.596707
HELZ helicase with zinc finger 0.596073
FAM135B family with sequence similarity 135, member B 0.595915
RPS7P5 ribosomal protein S7 pseudogene 5 0.595757
ACYP2 acylphosphatase 2, muscle type 0.595599
ZNF329 zinc finger protein 329 0.595442
KANK4 KN motif and ankyrin repeat domains 4 0.595129
CELF2 CUGBP, Elav-like family member 2 0.59466
NRF1 nuclear respiratory factor 1 0.594349
EPB41 erythrocyte membrane protein band 4.1 0.594038
TM4SF19 transmembrane 4 L six family member 19 0.593884
ADK adenosine kinase 0.593267
FLJ45872 0.592807
RELL1 RELT-like 1 0.592654
SZT2 seizure threshold 2 homolog (mouse) 0.592654
LOC100506178 uncharacterized LOC100506178 0.591893
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 0.591742
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 0.591742
NLRP13 NLR family, pyrin domain containing 13 0.591439
ACOXL acyl-CoA oxidase-like 0.591289
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.591289
DNAH11 dynein, axonemal, heavy chain 11 0.590838
CA10 carbonic anhydrase X 0.590389
LINGO2 leucine rich repeat and Ig domain containing 2 0.589645
FAM49B family with sequence similarity 49, member B 0.589054
IGSF5 immunoglobulin superfamily, member 5 0.589054
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.58876
HABP2 hyaluronan binding protein 2 0.588175
EPHB2 EPH receptor B2 0.588175
THSD7A thrombospondin, type I, domain containing 7A 0.587883
NADK2 NAD kinase 2, mitochondrial 0.587738
TSSC1 tumor suppressing subtransferable candidate 1 0.587592
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.587592
ZBTB17 zinc finger and BTB domain containing 17 0.586726
PDE4B phosphodiesterase 4B, cAMP-specific 0.586582
PRDM5 PR domain containing 5 0.585756
INPP1 inositol polyphosphate-1-phosphatase 0.585507
CD1E CD1e molecule 0.585259
IGF1R insulin-like growth factor 1 receptor 0.584766
LRRIQ1 leucine-rich repeats and IQ motif containing 1 0.584643
RYR3 ryanodine receptor 3 0.58452
ARHGAP22 Rho GTPase activating protein 22 0.58403
CRBN cereblon 0.583787
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.583665
FAM186A family with sequence similarity 186, member A 0.583422
DLG2 discs, large homolog 2 (Drosophila) 0.583059
COL15A1 collagen, type XV, alpha 1 0.582939
KDM4C lysine (K)-specific demethylase 4C 0.582698
BICD2 bicaudal D homolog 2 (Drosophila) 0.582578
MED27 mediator complex subunit 27 0.582338
ARMC1 armadillo repeat containing 1 0.582219
CSMD2 CUB and Sushi multiple domains 2 0.58198
COL22A1 collagen, type XXII, alpha 1 0.581623
FIP1L1 factor interacting with PAPOLA and CPSF1 0.581504
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 0.581268
SSPN sarcospan 0.580913
ACSL3 acyl-CoA synthetase long-chain family member 3 0.580796
GRB10 growth factor receptor-bound protein 10 0.580561
SPIDR scaffolding protein involved in DNA repair 0.580444
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 0.57986
NMNAT3 nicotinamide nucleotide adenylyltransferase 3 0.57986
CD8B CD8b molecule 0.579744
TUBGCP6 tubulin, gamma complex associated protein 6 0.579628
CAMTA1 calmodulin binding transcription activator 1 0.579512
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 0.579165
PAPPA2 pappalysin 2 0.578934
NOX4 NADPH oxidase 4 0.578934
NTM neurotrimin 0.578589
PAQR5 progestin and adipoQ receptor family member V 0.57836
COL25A1 collagen, type XXV, alpha 1 0.577904
SUMO4 small ubiquitin-like modifier 4 0.577677
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 0.577677
HLA-L major histocompatibility complex, class I, L (pseudogene) 0.576999
ZNF282 zinc finger protein 282 0.576774
DNAJB8-AS1 DNAJB8 antisense RNA 1 0.576774
ITGAV integrin, alpha V 0.576661
ARHGAP42 Rho GTPase activating protein 42 0.576214
LOC100506368 uncharacterized LOC100506368 0.575991
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.575991
COQ3 coenzyme Q3 methyltransferase 0.575769
EZR ezrin 0.575658
EPHA5 EPH receptor A5 0.575658
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.575216
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 0.575216
EFCAB5 EF-hand calcium binding domain 5 0.575216
CLEC16A C-type lectin domain family 16, member A 0.574885
WBSCR17 Williams-Beuren syndrome chromosome region 17 0.574885
COL9A1 collagen, type IX, alpha 1 0.574556
ZSWIM5 zinc finger, SWIM-type containing 5 0.574447
ATXN1 ataxin 1 0.574229
EGFR epidermal growth factor receptor 0.57412
EGFLAM EGF-like, fibronectin type III and laminin G domains 0.57412
ANTXR2 anthrax toxin receptor 2 0.573794
RAD54L2 RAD54-like 2 (S. cerevisiae) 0.573685
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.573685
SHISA6 shisa family member 6 0.573469
ROR1 receptor tyrosine kinase-like orphan receptor 1 0.572823
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.452848
CDYL2 chromodomain protein, Y-like 2 0.43465
TBX1 T-box 1 0.415184
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.408919
IPO7 importin 7 0.404235
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.393189
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase 0.390094
SLC26A11 solute carrier family 26 (anion exchanger), member 11 0.379087
RNF220 ring finger protein 220 0.373611
CHAT choline O-acetyltransferase 0.373016
STRN striatin, calmodulin binding protein 0.312675