abnormality of circulating hormone level Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An abnormal concentration of a hormone in the blood. (Human Phenotype Ontology, HP_0003117)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0003117
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Genes

118 genes associated with the abnormality of circulating hormone level phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
G6PC2 glucose-6-phosphatase, catalytic, 2 2.75223
MTNR1B melatonin receptor 1B 2.6162
HLA-C major histocompatibility complex, class I, C 2.06978
LCN12 lipocalin 12 1.90864
TRIM31 tripartite motif containing 31 1.73304
C8G complement component 8, gamma polypeptide 1.68095
FBXW5 F-box and WD repeat domain containing 5 1.66354
GCKR glucokinase (hexokinase 4) regulator 1.57193
LCNL1 lipocalin-like 1 1.43889
PTGDS prostaglandin D2 synthase 21kDa (brain) 1.37851
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 1.33272
HLA-B major histocompatibility complex, class I, B 1.25251
REEP3 receptor accessory protein 3 1.24751
C9ORF139 chromosome 9 open reading frame 139 1.19958
SH2B3 SH2B adaptor protein 3 1.19958
NPDC1 neural proliferation, differentiation and control, 1 1.19666
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 1.18141
ADCY5 adenylate cyclase 5 1.11323
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.04501
MADD MAP-kinase activating death domain 1.01822
CRY2 cryptochrome circadian clock 2 0.99729
FADS1 fatty acid desaturase 1 0.943205
GLIS3 GLIS family zinc finger 3 0.844241
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.702439
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.673563
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.548032
TRAF2 TNF receptor-associated factor 2 0.493579
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 0.435578
MRPL33 mitochondrial ribosomal protein L33 0.424122
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 0.40959
LEPR leptin receptor 0.405828
DPYSL5 dihydropyrimidinase-like 5 0.395108
GCK glucokinase (hexokinase 4) 0.394162
CREB5 cAMP responsive element binding protein 5 0.380609
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.376856
PCDH9 protocadherin 9 0.375159
LEPROT leptin receptor overlapping transcript 0.367232
IGF1 insulin-like growth factor 1 (somatomedin C) 0.360889
PDGFC platelet derived growth factor C 0.355735
ZMAT4 zinc finger, matrin-type 4 0.347284
TRAPPC9 trafficking protein particle complex 9 0.346692
GRB10 growth factor receptor-bound protein 10 0.338078
SUGCT succinyl-CoA:glutarate-CoA transferase 0.337502
PEPD peptidase D 0.337269
CFAP44 cilia and flagella associated protein 44 0.332681
PPARG peroxisome proliferator-activated receptor gamma 0.331439
SYN2 synapsin II 0.331439
RREB1 ras responsive element binding protein 1 0.328357
NOSTRIN nitric oxide synthase trafficking 0.327868
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.325387
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.324988
AKAP6 A kinase (PRKA) anchor protein 6 0.324241
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.322611
SPAG16 sperm associated antigen 16 0.322611
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.322464
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.321654
SULF1 sulfatase 1 0.321238
TNNI3 troponin I type 3 (cardiac) 0.320865
CDC5L cell division cycle 5-like 0.318624
ADCY2 adenylate cyclase 2 (brain) 0.318077
MTMR10 myotubularin related protein 10 0.317731
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.313585
LOC728755 uncharacterized LOC728755 0.313381
KDM2B lysine (K)-specific demethylase 2B 0.311139
CLSTN2 calsyntenin 2 0.306729
FOXN3 forkhead box N3 0.306729
ASIC2 acid sensing (proton gated) ion channel 2 0.306729
MGST3 microsomal glutathione S-transferase 3 0.306031
TENM4 teneurin transmembrane protein 4 0.305797
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.305699
TNS4 tensin 4 0.305064
DGKB diacylglycerol kinase, beta 90kDa 0.305064
PLXNA2 plexin A2 0.305064
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.303627
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.301756
PTCHD3 patched domain containing 3 0.300932
PRDM5 PR domain containing 5 0.300932
MOXD1 monooxygenase, DBH-like 1 0.296464
DNAH8 dynein, axonemal, heavy chain 8 0.296315
SNX29 sorting nexin 29 0.295351
ALCAM activated leukocyte cell adhesion molecule 0.293557
FKBP5 FK506 binding protein 5 0.291815
FAN1 FANCD2/FANCI-associated nuclease 1 0.291431
STON2 stonin 2 0.29
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.289888
SLC35F2 solute carrier family 35, member F2 0.289888
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 0.289129
TMED7-TICAM2 TMED7-TICAM2 readthrough 0.287737
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.287458
CNTNAP2 contactin associated protein-like 2 0.287458
PRKCA protein kinase C, alpha 0.287275
TMEM209 transmembrane protein 209 0.283527
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.282474
SH3RF2 SH3 domain containing ring finger 2 0.281713
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.279965
PRR16 proline rich 16 0.278825
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 0.278703
ZNF343 zinc finger protein 343 0.27732
LARGE like-glycosyltransferase 0.275177
TSHZ1 teashirt zinc finger homeobox 1 0.273734
ARHGAP24 Rho GTPase activating protein 24 0.273648
LTBP1 latent transforming growth factor beta binding protein 1 0.272859
TMEM135 transmembrane protein 135 0.27215
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 0.270143
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 0.267786
PHF21B PHD finger protein 21B 0.267272
NRG1 neuregulin 1 0.266652
TLK1 tousled-like kinase 1 0.265996
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.264787
ANTXR1 anthrax toxin receptor 1 0.264733
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 0.262754
STXBP4 syntaxin binding protein 4 0.262307
PVT1 Pvt1 oncogene (non-protein coding) 0.261515
ESRRG estrogen-related receptor gamma 0.261058
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 0.259274
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.257126
CCDC109B coiled-coil domain containing 109B 0.245263
ALK anaplastic lymphoma receptor tyrosine kinase 0.239768