abnormality of cells of the monocyte/macrophage lineage Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0012144
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Genes

92 genes associated with the abnormality of cells of the monocyte/macrophage lineage phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.02795
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.26492
IRF8 interferon regulatory factor 8 1.22503
CARD9 caspase recruitment domain family, member 9 1.1784
MARC1 mitochondrial amidoxime reducing component 1 1.11203
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.07729
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 1.04115
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.02002
LDLRAD3 low density lipoprotein receptor class A domain containing 3 0.91506
ZFAT zinc finger and AT hook domain containing 0.890336
WWC1 WW and C2 domain containing 1 0.841148
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 0.840142
PLXDC2 plexin domain containing 2 0.828053
EYA2 EYA transcriptional coactivator and phosphatase 2 0.814503
SGCZ sarcoglycan, zeta 0.777194
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.773374
SYT14 synaptotagmin XIV 0.763536
NRXN3 neurexin 3 0.758788
FAM212B family with sequence similarity 212, member B 0.758788
CDHR3 cadherin-related family member 3 0.756252
AFAP1 actin filament associated protein 1 0.755257
FER fer (fps/fes related) tyrosine kinase 0.740664
LOC100506944 uncharacterized LOC100506944 0.738585
MAN2A1 mannosidase, alpha, class 2A, member 1 0.732349
PODXL podocalyxin-like 0.724872
SRPK2 SRSF protein kinase 2 0.719063
GLIPR1 GLI pathogenesis-related 1 0.700393
LEMD3 LEM domain containing 3 0.698351
DNM3 dynamin 3 0.69768
TFDP1 transcription factor Dp-1 0.688431
C16ORF45 chromosome 16 open reading frame 45 0.684849
ING3 inhibitor of growth family, member 3 0.683974
PBX1 pre-B-cell leukemia homeobox 1 0.683395
TMC1 transmembrane channel-like 1 0.676616
MS4A14 membrane-spanning 4-domains, subfamily A, member 14 0.676316
EFCAB2 EF-hand calcium binding domain 2 0.675124
KIN Kin17 DNA and RNA binding protein 0.671627
SMAD7 SMAD family member 7 0.665245
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) 0.661032
RYR3 ryanodine receptor 3 0.65625
KIAA1715 KIAA1715 0.650291
DHRS12 dehydrogenase/reductase (SDR family) member 12 0.64937
UBASH3B ubiquitin associated and SH3 domain containing B 0.649139
PTPRD protein tyrosine phosphatase, receptor type, D 0.647367
LVRN laeverin 0.629413
LOC440704 uncharacterized LOC440704 0.623659
ITGB8 integrin, beta 8 0.621485
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.619547
COL4A1 collagen, type IV, alpha 1 0.613082
COL23A1 collagen, type XXIII, alpha 1 0.604135
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.601597
ARHGAP8 Rho GTPase activating protein 8 0.594972
CCR3 chemokine (C-C motif) receptor 3 0.594504
C5ORF63 chromosome 5 open reading frame 63 0.592807
COL19A1 collagen, type XIX, alpha 1 0.579165
ERBB4 erb-b2 receptor tyrosine kinase 4 0.578704
CXCR6 chemokine (C-X-C motif) receptor 6 0.575991
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.574995
LUZP2 leucine zipper protein 2 0.574447
PTGR1 prostaglandin reductase 1 0.443208
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.438519
PAX5 paired box 5 0.413807
HIGD1C HIG1 hypoxia inducible domain family, member 1C 0.408261
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.404458
EIF3L eukaryotic translation initiation factor 3, subunit L 0.40037
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 0.398821
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.398533
MTAP methylthioadenosine phosphorylase 0.397987
PAIP2B poly(A) binding protein interacting protein 2B 0.393645
INTS3 integrator complex subunit 3 0.393472
IL4I1 interleukin 4 induced 1 0.392761
SMOC2 SPARC related modular calcium binding 2 0.391795
RASGEF1A RasGEF domain family, member 1A 0.390876
CELF4 CUGBP, Elav-like family member 4 0.388852
NUP62 nucleoporin 62kDa 0.388796
XPO4 exportin 4 0.387332
UNC13C unc-13 homolog C (C. elegans) 0.3866
ATF5 activating transcription factor 5 0.384449
DGKH diacylglycerol kinase, eta 0.382519
PKN2 protein kinase N2 0.3803
LOC729950 uncharacterized LOC729950 0.379476
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.379376
KIAA0825 KIAA0825 0.37936
GPC6 glypican 6 0.379343
NTM neurotrimin 0.379147
PDZD2 PDZ domain containing 2 0.378529
CADPS Ca++-dependent secretion activator 0.378391
LRP1B low density lipoprotein receptor-related protein 1B 0.378315
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.377984
CSMD1 CUB and Sushi multiple domains 1 0.37794
GLT1D1 glycosyltransferase 1 domain containing 1 0.37759
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.376877