abnormality of b cells Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An abnormality of B cells. (Human Phenotype Ontology, HP_0002846)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0002846
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Genes

344 genes associated with the abnormality of b cells phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 2.35563
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.83749
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1.61257
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 1.5645
IL13 interleukin 13 1.33449
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.25001
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 1.19308
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 1.04365
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.02229
NCK2 NCK adaptor protein 2 0.964823
NFASC neurofascin 0.931243
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.931243
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.909907
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.808951
IFIH1 interferon induced with helicase C domain 1 0.741266
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 0.726078
CSMD1 CUB and Sushi multiple domains 1 0.706218
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.593319
LAMB1 laminin, beta 1 0.572823
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.542759
SLC38A10 solute carrier family 38, member 10 0.530444
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.522136
RAD50 RAD50 homolog (S. cerevisiae) 0.522136
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 0.515847
IL4R interleukin 4 receptor 0.495598
SEPHS1 selenophosphate synthetase 1 0.495598
FXR2 fragile X mental retardation, autosomal homolog 2 0.474018
ALDH1L2 aldehyde dehydrogenase 1 family, member L2 0.474018
LINC00299 long intergenic non-protein coding RNA 299 0.474018
CLEC16A C-type lectin domain family 16, member A 0.474018
RYR2 ryanodine receptor 2 (cardiac) 0.4604
MX1 MX dynamin-like GTPase 1 0.4604
SNORD48 small nucleolar RNA, C/D box 48 0.4604
CEP131 centrosomal protein 131kDa 0.450694
EGF epidermal growth factor 0.450694
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 0.450694
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.450694
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.450694
LRRTM4 leucine rich repeat transmembrane neuronal 4 0.450694
FOXP2 forkhead box P2 0.443208
RELL1 RELT-like 1 0.437499
ARMC3 armadillo repeat containing 3 0.437499
SNTG1 syntrophin, gamma 1 0.437499
HLA-A major histocompatibility complex, class I, A 0.436934
LRP1 low density lipoprotein receptor-related protein 1 0.435087
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 0.433116
CLRN1-AS1 CLRN1 antisense RNA 1 0.433116
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.432202
AAA1 aortic aneurysm, familial abdominal 1 0.429354
ZBTB39 zinc finger and BTB domain containing 39 0.428322
EPAS1 endothelial PAS domain protein 1 0.424122
KCNIP4 Kv channel interacting protein 4 0.424122
IL2 interleukin 2 0.424122
STAB2 stabilin 2 0.424122
ITGA11 integrin, alpha 11 0.424122
TRIM5 tripartite motif containing 5 0.424122
SGCZ sarcoglycan, zeta 0.424122
ELL2 elongation factor, RNA polymerase II, 2 0.424122
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.424122
ARID5B AT rich interactive domain 5B (MRF1-like) 0.424122
VAV2 vav 2 guanine nucleotide exchange factor 0.424122
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 0.413807
CPNE8 copine VIII 0.413807
COL19A1 collagen, type XIX, alpha 1 0.413807
GLI3 GLI family zinc finger 3 0.413807
TMEM132D transmembrane protein 132D 0.413807
LOC729911 0.413807
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.413807
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 0.413807
LOC286190 0.413807
SHISA6 shisa family member 6 0.413807
SBF1 SET binding factor 1 0.413807
EPS15 epidermal growth factor receptor pathway substrate 15 0.413807
LPP LIM domain containing preferred translocation partner in lipoma 0.413807
SLIT1 slit homolog 1 (Drosophila) 0.413807
DGKZ diacylglycerol kinase, zeta 0.413807
SMYD2 SET and MYND domain containing 2 0.413807
SMYD1 SET and MYND domain containing 1 0.413807
PARVB parvin, beta 0.413807
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.413807
CCDC40 coiled-coil domain containing 40 0.413807
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.413441
COL26A1 collagen, type XXVI, alpha 1 0.411483
POU6F2 POU class 6 homeobox 2 0.410331
CNTNAP5 contactin associated protein-like 5 0.410331
CTIF CBP80/20-dependent translation initiation factor 0.410331
TRIM6 tripartite motif containing 6 0.410331
PRKG1 protein kinase, cGMP-dependent, type I 0.410331
DNAH5 dynein, axonemal, heavy chain 5 0.410331
LINC00469 long intergenic non-protein coding RNA 469 0.410331
MDC1 mediator of DNA-damage checkpoint 1 0.410331
SKI SKI proto-oncogene 0.410331
PTPRT protein tyrosine phosphatase, receptor type, T 0.410331
ANGPT1 angiopoietin 1 0.410331
SORBS1 sorbin and SH3 domain containing 1 0.410331
EYS eyes shut homolog (Drosophila) 0.410331
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase 0.410331
REC114 REC114 meiotic recombination protein 0.408206
AGR2 anterior gradient 2 0.408206
ZNF423 zinc finger protein 423 0.408206
ELMO1 engulfment and cell motility 1 0.408206
NRG3 neuregulin 3 0.408206
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 0.408206
LOC100505940 0.408206
GFRA1 GDNF family receptor alpha 1 0.408206
CDH13 cadherin 13 0.408206
TOPAZ1 testis and ovary specific PAZ domain containing 1 0.408206
LINGO2 leucine rich repeat and Ig domain containing 2 0.408206
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.408206
ETV6 ets variant 6 0.408206
CHD2 chromodomain helicase DNA binding protein 2 0.408206
AUTS2 autism susceptibility candidate 2 0.408206
JAKMIP1 janus kinase and microtubule interacting protein 1 0.408206
PLD5 phospholipase D family, member 5 0.408206
LBR lamin B receptor 0.408206
ABI3 ABI family, member 3 0.408206
CDK18 cyclin-dependent kinase 18 0.408206
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.406588
SCUBE1 signal peptide, CUB domain, EGF-like 1 0.406588
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.406588
CNTN1 contactin 1 0.406588
ZNF804B zinc finger protein 804B 0.406588
GPM6A glycoprotein M6A 0.406588
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.406588
LBP lipopolysaccharide binding protein 0.406588
FRY furry homolog (Drosophila) 0.406588
ANO2 anoctamin 2, calcium activated chloride channel 0.406588
LRRC4C leucine rich repeat containing 4C 0.406588
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.406588
FMNL2 formin-like 2 0.406588
PARK2 parkin RBR E3 ubiquitin protein ligase 0.406588
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 0.406588
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 0.406588
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.406588
ACO1 aconitase 1, soluble 0.406588
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.406588
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 0.406588
TMEM182 transmembrane protein 182 0.406588
C5ORF56 chromosome 5 open reading frame 56 0.405331
EFCAB6 EF-hand calcium binding domain 6 0.405267
FAS Fas cell surface death receptor 0.405267
GRM3 glutamate receptor, metabotropic 3 0.405267
CNN1 calponin 1, basic, smooth muscle 0.405267
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.405267
MPRIP myosin phosphatase Rho interacting protein 0.405267
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.405267
FOXP1 forkhead box P1 0.405267
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.405267
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.405267
LOC100132735 uncharacterized LOC100132735 0.405267
MTSS1 metastasis suppressor 1 0.405267
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.40409
CEP170B centrosomal protein 170B 0.40409
DNAH10 dynein, axonemal, heavy chain 10 0.40409
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa 0.40409
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.40409
BEND7 BEN domain containing 7 0.40409
SYT9 synaptotagmin IX 0.40409
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 0.40409
GPR158 G protein-coupled receptor 158 0.40409
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 0.40409
DNAL4 dynein, axonemal, light chain 4 0.40409
SIK2 salt-inducible kinase 2 0.403178
DNER delta/notch-like EGF repeat containing 0.403073
ATF6 activating transcription factor 6 0.403073
HUNK hormonally up-regulated Neu-associated kinase 0.403073
TMEM255B transmembrane protein 255B 0.403073
CNTNAP2 contactin associated protein-like 2 0.403073
TTLL2 tubulin tyrosine ligase-like family member 2 0.403073
DNASE2B deoxyribonuclease II beta 0.403073
MON2 MON2 homolog (S. cerevisiae) 0.403073
TEK TEK tyrosine kinase, endothelial 0.403073
LOC100132731 uncharacterized LOC100132731 0.403073
IGFBP7 insulin-like growth factor binding protein 7 0.403073
PROX2 prospero homeobox 2 0.403073
PAPD4 PAP associated domain containing 4 0.403073
SYNGR1 synaptogyrin 1 0.403073
PRKD1 protein kinase D1 0.403073
TBC1D14 TBC1 domain family, member 14 0.403073
HRH1 histamine receptor H1 0.403073
CADPS Ca++-dependent secretion activator 0.403073
LOC643962 uncharacterized LOC643962 0.403073
PTPRR protein tyrosine phosphatase, receptor type, R 0.402177
MEF2BNB-MEF2B MEF2BNB-MEF2B readthrough 0.402177
PTGFR prostaglandin F receptor (FP) 0.402177
PRICKLE2 prickle homolog 2 (Drosophila) 0.402177
LRP1B low density lipoprotein receptor-related protein 1B 0.402177
RAB3C RAB3C, member RAS oncogene family 0.402177
PLCH1 phospholipase C, eta 1 0.402177
MEGF10 multiple EGF-like-domains 10 0.402177
DOCK2 dedicator of cytokinesis 2 0.402177
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.402177
UMODL1 uromodulin-like 1 0.402177
EMC9 ER membrane protein complex subunit 9 0.402177
PNOC prepronociceptin 0.402177
UBAP2 ubiquitin associated protein 2 0.40216
HLA-H major histocompatibility complex, class I, H (pseudogene) 0.401896
ZNRD1-AS1 ZNRD1 antisense RNA 1 0.401847
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.400228
C2ORF83 chromosome 2 open reading frame 83 0.400158
HLA-J major histocompatibility complex, class I, J (pseudogene) 0.400021
HDAC4 histone deacetylase 4 0.399304
CASR calcium-sensing receptor 0.399059
NRCAM neuronal cell adhesion molecule 0.398704
HSF2BP heat shock transcription factor 2 binding protein 0.397645
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.397588
MSI2 musashi RNA-binding protein 2 0.397418
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.397197
DOT1L DOT1-like histone H3K79 methyltransferase 0.396463
MICA MHC class I polypeptide-related sequence A 0.396463
TBC1D31 TBC1 domain family, member 31 0.396216
PCDH15 protocadherin-related 15 0.395833
CD86 CD86 molecule 0.39507
CARD14 caspase recruitment domain family, member 14 0.393645
MAK male germ cell-associated kinase 0.393559
TRIM26 tripartite motif containing 26 0.393048
C17ORF99 chromosome 17 open reading frame 99 0.393048
LAMC3 laminin, gamma 3 0.391981
NRP1 neuropilin 1 0.391869
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.391185
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.391047
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.391012
FMN2 formin 2 0.390944
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 0.39091
CSTA cystatin A (stefin A) 0.390876
RFC3 replication factor C (activator 1) 3, 38kDa 0.390478
LOC440600 uncharacterized LOC440600 0.38925
MTCL1 microtubule crosslinking factor 1 0.38925
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.388964
SHROOM3 shroom family member 3 0.388769
CNTN4 contactin 4 0.388142
MYH13 myosin, heavy chain 13, skeletal muscle 0.388049
MAP2 microtubule-associated protein 2 0.387246
EDAR ectodysplasin A receptor 0.387102
FAM162A family with sequence similarity 162, member A 0.386738
FAXC failed axon connections homolog (Drosophila) 0.386682
ECT2L epithelial cell transforming 2 like 0.386627
IRF8 interferon regulatory factor 8 0.386356
HCG9 HLA complex group 9 (non-protein coding) 0.386197
TMPRSS7 transmembrane protease, serine 7 0.386013
DRD2 dopamine receptor D2 0.385578
CDK6 cyclin-dependent kinase 6 0.385553
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 0.385304
CD80 CD80 molecule 0.385231
C15ORF40 chromosome 15 open reading frame 40 0.384704
GSK3B glycogen synthase kinase 3 beta 0.384472
LVRN laeverin 0.384404
KCNIP1 Kv channel interacting protein 1 0.384313
OR10J1 olfactory receptor, family 10, subfamily J, member 1 0.384066
RELN reelin 0.383911
ASTL astacin-like metallo-endopeptidase (M12 family) 0.383824
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.383291
GDE1 glycerophosphodiester phosphodiesterase 1 0.382881
RORA RAR-related orphan receptor A 0.382841
ETV5 ets variant 5 0.382373
PARP9 poly (ADP-ribose) polymerase family, member 9 0.382331
PTPDC1 protein tyrosine phosphatase domain containing 1 0.382064
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.381823
KIF26B kinesin family member 26B 0.381704
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.381469
ADGRB1 adhesion G protein-coupled receptor B1 0.381295
PTPRG protein tyrosine phosphatase, receptor type, G 0.381219
AHI1 Abelson helper integration site 1 0.381086
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.380936
ARHGAP31 Rho GTPase activating protein 31 0.379916
TRIM31 tripartite motif containing 31 0.379677
SRL sarcalumenin 0.379576
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.379492
SETBP1 SET binding protein 1 0.379082
CADM3 cell adhesion molecule 3 0.378779
CELF1 CUGBP, Elav-like family member 1 0.378685
FGGY FGGY carbohydrate kinase domain containing 0.378623
GRM5 glutamate receptor, metabotropic 5 0.378499
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.3783
MAP6D1 MAP6 domain containing 1 0.378074
OSBPL10 oxysterol binding protein-like 10 0.378029
ZNF622 zinc finger protein 622 0.377691
KPNA1 karyopherin alpha 1 (importin alpha 5) 0.377405
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 0.377194
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.376634
MARC1 mitochondrial amidoxime reducing component 1 0.376139
TK1 thymidine kinase 1, soluble 0.375889
RYR3 ryanodine receptor 3 0.375403
LRP6 low density lipoprotein receptor-related protein 6 0.374594
PDE4D phosphodiesterase 4D, cAMP-specific 0.374594
MYO18B myosin XVIIIB 0.374483
FOXN3 forkhead box N3 0.374373
DACH2 dachshund family transcription factor 2 0.373835
RAB11FIP4 RAB11 family interacting protein 4 (class II) 0.37373
ZNF185 zinc finger protein 185 (LIM domain) 0.373319
PHACTR2 phosphatase and actin regulator 2 0.37302
CAMKMT calmodulin-lysine N-methyltransferase 0.372824
DNMBP dynamin binding protein 0.37207
ARHGAP30 Rho GTPase activating protein 30 0.371709
GLIS3 GLIS family zinc finger 3 0.371187
RHBG Rh family, B glycoprotein (gene/pseudogene) 0.370363
CD46 CD46 molecule, complement regulatory protein 0.370283
FAM167A family with sequence similarity 167, member A 0.369737
CCDC50 coiled-coil domain containing 50 0.369361
MYEOV2 myeloma overexpressed 2 0.369214
GUCD1 guanylyl cyclase domain containing 1 0.368996
C1ORF87 chromosome 1 open reading frame 87 0.368433
CNTN6 contactin 6 0.368433
NCAM1 neural cell adhesion molecule 1 0.368093
ARHGAP21 Rho GTPase activating protein 21 0.367894
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.367828
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 0.367828
TMEM30C transmembrane protein 30C 0.367763
GREM2 gremlin 2, DAN family BMP antagonist 0.367633
CHD6 chromodomain helicase DNA binding protein 6 0.367127
LOC646736 uncharacterized LOC646736 0.365944
GXYLT1 glucoside xylosyltransferase 1 0.365286
ELL elongation factor RNA polymerase II 0.365074
NUB1 negative regulator of ubiquitin-like proteins 1 0.364969
TACR1 tachykinin receptor 1 0.364813
RSU1 Ras suppressor protein 1 0.36466
SULF2 sulfatase 2 0.364559
TPRG1 tumor protein p63 regulated 1 0.364508
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.364458
TECR trans-2,3-enoyl-CoA reductase 0.364211
DYSF dysferlin 0.364113
SORBS2 sorbin and SH3 domain containing 2 0.364064
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.363651
APCDD1L adenomatosis polyposis coli down-regulated 1-like 0.362438
FBLN1 fibulin 1 0.362392
CHODL chondrolectin 0.361849
TULP4 tubby like protein 4 0.361073
MRPL53 mitochondrial ribosomal protein L53 0.360341
CLHC1 clathrin heavy chain linker domain containing 1 0.360262
MOGS mannosyl-oligosaccharide glucosidase 0.359874
B3GALTL beta 1,3-galactosyltransferase-like 0.359798
PCLO piccolo presynaptic cytomatrix protein 0.35935
RRP1B ribosomal RNA processing 1B 0.359276
NALCN sodium leak channel, non selective 0.359131
MYO5C myosin VC 0.358775
KCTD14 potassium channel tetramerization domain containing 14 0.358023
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.357492
CDH23 cadherin-related 23 0.357214
RAD51B RAD51 paralog B 0.356873
IYD iodotyrosine deiodinase 0.355586
CHN2 chimerin 2 0.352873
MUC22 mucin 22 0.352299
LINC00547 long intergenic non-protein coding RNA 547 0.351193
KIAA1107 KIAA1107 0.350174