abnormal visceral endoderm morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the primitive endoderm-derived tissue which remains in contact with and surrounds the extra-embryonic ectoderm and the epiblast and provides signals for the differentiation and patterning of the epiblast; a small number of visceral endoderm cells also contribute to the endoderm of the embryonic gut (Mammalian Phenotype Ontology, MP_0011186)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011186
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Genes

54 gene mutations causing the abnormal visceral endoderm morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACVR1 activin A receptor, type I
ACVR1B activin A receptor, type IB
AMOT angiomotin
APC adenomatous polyposis coli
ARC activity-regulated cytoskeleton-associated protein
ARF4 ADP-ribosylation factor 4
BMPR1A bone morphogenetic protein receptor, type IA
BPTF bromodomain PHD finger transcription factor
BRCA1 breast cancer 1, early onset
CENPU centromere protein U
CNBP CCHC-type zinc finger, nucleic acid binding protein
CUBN cubilin (intrinsic factor-cobalamin receptor)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAD1 defender against cell death 1
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DLD dihydrolipoamide dehydrogenase
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FLRT3 fibronectin leucine rich transmembrane protein 3
FOSL1 FOS-like antigen 1
FRS2 fibroblast growth factor receptor substrate 2
GATA6 GATA binding protein 6
GDF3 growth differentiation factor 3
HHEX hematopoietically expressed homeobox
HNF1B HNF1 homeobox B
HTT huntingtin
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
LAMA1 laminin, alpha 1
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
MAPK1 mitogen-activated protein kinase 1
MED12 mediator complex subunit 12
MESDC2 mesoderm development candidate 2
MYH9 myosin, heavy chain 9, non-muscle
NF2 neurofibromin 2 (merlin)
NODAL nodal growth differentiation factor
NR5A2 nuclear receptor subfamily 5, group A, member 2
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIKFYVE phosphoinositide kinase, FYVE finger containing
PKNOX1 PBX/knotted 1 homeobox 1
POFUT2 protein O-fucosyltransferase 2
POU2F1 POU class 2 homeobox 1
PPAP2B phosphatidic acid phosphatase type 2B
QKI QKI, KH domain containing, RNA binding
RAB7A RAB7A, member RAS oncogene family
RYBP RING1 and YY1 binding protein
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
TDGF1 teratocarcinoma-derived growth factor 1
TRIM33 tripartite motif containing 33
TSG101 tumor susceptibility 101
TXNRD1 thioredoxin reductase 1
ZFR zinc finger RNA binding protein
ZIC3 Zic family member 3