abnormal vertebral arch morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the dorsal bony and/or cartilaginous part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process) (Mammalian Phenotype Ontology, MP_0004599)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004599
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79 gene mutations causing the abnormal vertebral arch morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACP2 acid phosphatase 2, lysosomal
AFF3 AF4/FMR2 family, member 3
APAF1 apoptotic peptidase activating factor 1
ARID4A AT rich interactive domain 4A (RBP1-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
BMP4 bone morphogenetic protein 4
BMP5 bone morphogenetic protein 5
BMPER BMP binding endothelial regulator
C21ORF62 chromosome 21 open reading frame 62
CDX1 caudal type homeobox 1
CHRD chordin
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
COL12A1 collagen, type XII, alpha 1
COL2A1 collagen, type II, alpha 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
CSRP2BP CSRP2 binding protein
DLL3 delta-like 3 (Drosophila)
DNM3OS DNM3 opposite strand/antisense RNA
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1
EVC Ellis van Creveld protein
FGF9 fibroblast growth factor 9
FKBP8 FK506 binding protein 8, 38kDa
FOSL2 FOS-like antigen 2
FOXC1 forkhead box C1
FOXC2 forkhead box C2
FTO fat mass and obesity associated
GLI3 GLI family zinc finger 3
GRHL3 grainyhead-like 3 (Drosophila)
HES7 hes family bHLH transcription factor 7
HOXB2 homeobox B2
HOXD10 homeobox D10
ITGB1BP1 integrin beta 1 binding protein 1
KMT2A lysine (K)-specific methyltransferase 2A
LASP1 LIM and SH3 protein 1
LMX1A LIM homeobox transcription factor 1, alpha
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP6 low density lipoprotein receptor-related protein 6
MDFI MyoD family inhibitor
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2
MYF5 myogenic factor 5
MYSM1 Myb-like, SWIRM and MPN domains 1
NKX3-2 NK3 homeobox 2
NOG noggin
PAX1 paired box 1
PDGFC platelet derived growth factor C
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PKD1 polycystic kidney disease 1 (autosomal dominant)
POFUT1 protein O-fucosyltransferase 1
PSEN1 presenilin 1
RAB23 RAB23, member RAS oncogene family
RAI1 retinoic acid induced 1
RARA retinoic acid receptor, alpha
RARB retinoic acid receptor, beta
RARG retinoic acid receptor, gamma
RIPPLY2 ripply transcriptional repressor 2
RPL38 ribosomal protein L38
RPS7 ribosomal protein S7
SEC23A Sec23 homolog A (S. cerevisiae)
SEPN1 selenoprotein N, 1
SGPL1 sphingosine-1-phosphate lyase 1
SLC44A5 solute carrier family 44, member 5
STARD5 StAR-related lipid transfer (START) domain containing 5
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
SUZ12 SUZ12 polycomb repressive complex 2 subunit
T T, brachyury homolog (mouse)
TACC3 transforming, acidic coiled-coil containing protein 3
TBX1 T-box 1
TBX15 T-box 15
TBX18 T-box 18
TBX6 T-box 6
TGFB2 transforming growth factor, beta 2
TRAF4 TNF receptor-associated factor 4
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TSHZ1 teashirt zinc finger homeobox 1
TULP3 tubby like protein 3
TWSG1 twisted gastrulation BMP signaling modulator 1
UNCX UNC homeobox
VANGL2 VANGL planar cell polarity protein 2
ZIC2 Zic family member 2