abnormal vascular resistance Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description deviation from the normal force opposing the flow of blood through a vascular bed; it is equal to the difference in blood pressure across the vascular bed divided by the cardiac output (Mammalian Phenotype Ontology, MP_0005532)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005532
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Genes

15 gene mutations causing the abnormal vascular resistance phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGTR2 angiotensin II receptor, type 2
APOE apolipoprotein E
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CALCB calcitonin-related polypeptide beta
CYBB cytochrome b-245, beta polypeptide
KCNK6 potassium channel, two pore domain subfamily K, member 6
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH3 notch 3
NPPA natriuretic peptide A
NT5E 5'-nucleotidase, ecto (CD73)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)