abnormal vagus nerve morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the autonomic, sensory and motor axons of the tenth cranial nerve; it is primarily sensory but also has visceromotor components; it originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components, and also controls some motor functions such as speech; the sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis (Mammalian Phenotype Ontology, MP_0001074)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001074
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Genes

22 gene mutations causing the abnormal vagus nerve morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
CHD7 chromodomain helicase DNA binding protein 7
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
DST dystonin
EGR2 early growth response 2
ERBB2 erb-b2 receptor tyrosine kinase 2
FBLN1 fibulin 1
GBX2 gastrulation brain homeobox 2
GRB2 growth factor receptor-bound protein 2
HOXA1 homeobox A1
HOXA2 homeobox A2
HOXA3 homeobox A3
HOXB3 homeobox B3
LMO4 LIM domain only 4
MEGF8 multiple EGF-like-domains 8
NKX2-8 NK2 homeobox 8
NRG1 neuregulin 1
PHOX2B paired-like homeobox 2b
PLXNA4 plexin A4
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
TBX1 T-box 1