abnormal tubuloglomerular feedback response Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in the blood flow control mechanism that is operated in the juxtaglomerular apparatus of the kidney and involved in renal autoregulation by limiting changes in the glomerular filtration rate. TGF responds to changes in the concentration of NaCl in the tubular fluid at the level of the macula densa (Mammalian Phenotype Ontology, MP_0011295)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011295
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Genes

3 gene mutations causing the abnormal tubuloglomerular feedback response phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADORA1 adenosine A1 receptor
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1